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Nexofex Syrup is usually given to children to treat a wide range of symptoms caused due to allergic conditions such as hay fever, urticaria (hives), conjunctivitis (red, itchy eye), and common cold. These symptoms include watery eyes, runny nose, sneezing, and itching among others.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 19 Sep 2025 | 03:30 PM (IST)
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General Information

The content is shown in English
Nexofex Syrup image
Nexofex Syrup image

Your child’s medicine at a glance

Give Nexofex Syrup to your child by mouth with or without food in the dose and way prescribed by the doctor. It may be prescribed alone or in combination with other medicines. The allergic symptoms may subside after your child has taken the initial few doses of Nexofex Syrup. In case of serious allergic conditions, your child may have to continue taking the medicine for a week or two. If your child vomits within 30 minutes of taking this medicine, let the child calm down and give the same dose again. However, do not repeat the dose if it is already time for the next dose.

The intake of the medicine may cause some minor and temporary side effects like nausea, vomiting, dizziness, sleepiness, and headache. These side effects should ideally diminish on their own. But, in case they persist or start bothering your child, it would be best to consult your child’s doctor without any delay.

Inform your child’s doctor if your child is on any medical regime or is allergic to any medicine, product, or food. Make sure the doctor knows if your child has or had any heart, liver, kidney problems or was born prematurely. Any history regarding bowel obstruction, malnutrition, weight-related issues, and thyroid problems should also be well indicated to the doctor to avoid any complications in the treatment. Knowing the entire medical history will help your child’s doctor make dose alterations and plan your child’s overall treatment better.

Uses of Nexofex Syrup in children

Benefits of Nexofex Syrup for your child

Treatment of Sneezing and runny nose due to allergies
Nexofex Syrup provides relief from symptoms such as sneezing, itching, watery eyes, and runny nose. This will make it easier for you to go about your daily activities. It rarely has any serious side effects and you may only need to take it on days you have symptoms. If you are taking it to prevent getting symptoms you should use it regularly to get the most benefit.

Side effects of Nexofex Syrup in children

Nexofex Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Nexofex
  • Dizziness
  • Headache
  • Drowsiness
  • Nausea

How can I give Nexofex Syrup to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Nexofex Syrup may be taken with or without food, but it is better to take it at a fixed time.

How Nexofex Syrup works

Nexofex Syrup belongs to a class of medicines called antihistamines It blocks the natural chemical substance (histamine) produced in the body during an allergic state and subsides (lowers) your child’s immune system’s response to these conditions.

Quick tips

  • Try giving the medicines at the same time each day, to help you remember.
  • Your child may feel sleepy or dizzy after each dose of Nexofex Syrup. If this happens, make your child sit or lie down and ask them to be careful while performing tasks that require mental focus.
  • Avoid giving Nexofex Syrup with fatty meals and fruit juice as both can reduce the absorption of the medicine.
  • Nexofex Syrup should be avoided in children who are less than 12 years of age as there is a risk of respiratory distress.
  • Practice self-care tips:
    1. Abstain your child from coming in contact with allergens.
    2. Maintain a neat and clean ambiance around your child.
    3. Encourage your child to wear a face mask and avoid dusty places.
    4. Use of air conditioners instead of opening windows during the pollen season.
  • Nexofex Syrup may cause less sleepiness as a side effect compared to other similar medicines.
  • Avoid drinking fruit juices (such as apple or orange) as this may affect the absorption of this medicine and cause more side effects.
  • It may cause nausea. Stick to simple meals, and do not eat rich or spicy food.
  • Avoid using antacids 30 minutes before or after taking this medicine. It can make it harder for your body to absorb this medicine.
  • Never give the medicine to someone who seems to be suffering from a similar illness. This medicine should be taken only if prescribed by a doctor.
  • Your doctor has prescribed Nexofex Syrup to help relieve allergy symptoms such as itching, swelling and rashes.
  • As compared to other similar medications, it is much less likely to make you feel sleepy.
  • Be cautious while driving or doing anything that requires concentration as it can cause dizziness and sleepiness.
  • Do not drink alcohol while taking this medication as it may cause increased sleepiness.
  • Stop taking Nexofex Syrup at least 3 days before taking an allergy test as it can affect the test results.

Safety advice

Kidney

Kidney

CAUTION
Nexofex Syrup should be used with caution in patients with kidney disease. Dose adjustment of Nexofex Syrup may be needed. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Nexofex Syrup is safe to use in patients with liver disease. No dose adjustment of Nexofex Syrup is recommended.
However, consult your child's doctor before giving Nexofex Syrup to your child in case of severe liver disease.

Interaction with drugs

Taking Nexofex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tepotinib (Oral Route)

Do not consume Tepotinib with Fexofenadine. If concurrent use is essential, please consult your doctor. Tepotinib may raise blood levels of Fexofenadine.
Moderate

Leflunomide (Oral Route)

Watch out for symptoms of Fexofenadine side effects such as headaches, excessive sleepiness, dry mouth, feeling sick or dizziness and consult your doctor if you experience them. They may adjust the doses as per the observations. Leflunomide may raise blood levels of Fexofenadine.
Moderate

Ulipristal acetate (Oral Route)

Ensure a gap of at least 2 hours between taking Ulipristal acetate and Fexofenadine.
Moderate

Thalidomide (Oral Route)

If concurrent use is essential, watch out for symptoms of Thalidomide side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Moderate

Dronedarone (Oral Route)

Watch out for symptoms of Fexofenadine side effects such as headaches, excessive sleepiness, dry mouth, feeling sick or dizziness and consult your doctor if you experience them. They may adjust the doses as per the observations. Dronedarone may raise blood levels of Fexofenadine.

Frequently asked questions

Nexofex Syrup is used for treating seasonal allergic conditions such as hay fever. It helps to relieve allergies of the nose (allergic rhinitis), sneezing, runny nose, itching in the eyes, excessively watery eyes, etc.
Nexofex Syrup should not be given to patients with known allergy to any other ingredients of this medicine. Signs of an allergic reaction may include an itchy skin rash, shortness of breath, and swelling of the face or tongue.
Nexofex Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Nexofex Syrup. Also, check with your child’s doctor before giving any medicine to your child.
Avoid giving Nexofex Syrup with fatty meals and fruit juices as both can reduce the absorption of the medicine from the gut. If you need to give it to your child, ensure a gap of at least 4 hours to decrease any possible medicine-food interaction.
Nexofex Syrup should be given strictly as prescribed by your child’s doctor. The dose of the medicine is calculated according to your child’s body weight and age. Do not increase or decrease the dose on your own as it may cause unwanted effects and can worsen your child’s condition.
No, refrain from giving Nexofex Syrup to your child to induce sleep. Sleeplessness could be due to some other problem. Unnecessary use of Nexofex Syrup may lead to side effects. It is best to consult your doctor if your child cannot sleep or if you have any queries regarding the use of this medicine.
Keep Nexofex Syrup at room temperature, in a dry place, away from direct heat and light. Always keep all medicines out of the reach and sight of children to avoid any accidental intake.
Nexofex Syrup is used for treating seasonal allergic conditions such as hay fever. It helps to relieve allergies of the nose (allergic rhinitis), sneezing, runny nose, itching in the eyes, excessively watery eyes, etc.
Before starting treatment with Nexofex Syrup, tell your doctor if you have any other health problems, like kidneys, heart or liver-related issues. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Additionally, let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Also, inform your doctor if you are planning a baby, are pregnant, or breastfeeding.
If you forget a dose of Nexofex Syrup, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Nexofex Syrup should not be given to patients with known allergy to any other ingredients of this medicine. Signs of an allergic reaction may include an itchy skin rash, shortness of breath, and swelling of the face or tongue.
No. You should not stop taking Nexofex Syrup even if you feel better unless your doctor tells you to stop taking it. This is because, stopping the medicine suddenly, without completing your full course of treatment may cause the returning of your symptoms and it can even worsen your condition. Consult your doctor if you are not sure.
No. Nexofex Syrup is not an antibiotic. It is an anti-allergy medicine and helps to treat allergic conditions such as sneezing, stuffy or runny nose, hives, etc. On the other hand, antibiotics are used to treat infections caused by bacteria.
Yes, Nexofex Syrup can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, do not drive or use any machines. It is better to rest for some time and resume once you feel better.

Fact Box

Chemical Class

Diphenylmethane Derivative

Habit Forming

No

Therapeutic Class

RESPIRATORY

Action Class

Second-Generation H1 Antihistamines

References

  1. RA Skidgel. Histamine, Bradykinin, and Their Antagonists. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 13th ed. New York, New York: McGraw-Hill Medical; 2018. p. 718.
  2. Golisano Children's Hospital. Treatment for a Child's Allergy to Pollen or Animals. [Accessed 22 Jan. 2021] (online) Available from:
  3. National Health Services. Fexofenadine. [Last Reviewed: 14 Oct. 2021]. [Accessed 26 June 2023] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Emenox Healthcare
Address: Premises Nos. 1 to 8, 1st Floor, “ Ratna Umed Residency ”, Above Union Bank of India, Plot No.117, Umed Nagar, Louis Wadi, Thane.(w) 400604., Taluka and District – Thane, MUMBAI

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Nexofex Syrup. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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