Monotrate 20 Tablet
Prescription Required
41% cheaper alternative available with same salt composition
Product introduction
Monotrate 20 Tablet is used to prevent heart-related chest pain (angina). It works by relaxing and widening blood vessels so blood can flow more easily to the heart. This medicine will not treat an angina attack that has already begun.
Monotrate 20 Tablet may be taken with or without food. Your doctor will decide the dose and how often you should take it. The dose may change from time to time depending on how well the medicine works. Take this medicine exactly as prescribed and continue taking it even if you feel well. It helps prevent chest pain in the future. If you stop taking it, your risk of chest pain may increase, especially if you stop suddenly. Lifestyle changes such as a healthy diet, regular exercise, and avoiding smoking may help this medicine work better.
You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to dosing schedule to prevent this from happening.
The most common side effects include headache, flushing, upper respiratory tract infection, abdominal pain, allergic reaction, chest pain, and diarrhea. If these symptoms bother you or do not go away, your doctor may suggest ways of preventing or reducing them. Some can be reduced by taking painkillers, drinking plenty of fluids, and avoiding alcohol.
Before taking Monotrate 20 Tablet, tell your doctor if you have low blood pressure, glaucoma (increased pressure in the eye), kidney disease, or heart failure. Also, inform your doctor about any other medicines you are taking, as some may interact with this medicine or make it unsafe to use together. Do not take medicines for erectile dysfunction while using this medicine. If you are pregnant or breastfeeding, ask your doctor whether this medicine is suitable for you. Your doctor may regularly monitor your blood pressure and heart rate during treatment.
Uses of Monotrate Tablet
Benefits of Monotrate Tablet
In Treatment of Angina (heart-related chest pain)
Angina is chest pain caused by reduced blood flow to the heart muscle, usually due to narrowed coronary arteries. Monotrate 20 Tablet helps by relaxing and widening blood vessels, which improves blood flow and oxygen supply to the heart. This helps relieve chest discomfort and reduces the risk of angina attacks.
Side effects of Monotrate Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Monotrate
- Headache
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Upper respiratory tract infection
- Abdominal pain
- Chest pain
- Diarrhea
How to use Monotrate Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Monotrate 20 Tablet may be taken with or without food.
How Monotrate Tablet works
Monotrate 20 Tablet is a nitrate. It dilates peripheral arteries and veins. Dilation of the veins promotes peripheral pooling of blood and decreases venous return to the heart, thereby reducing the workload of the heart. As a result, the heart muscle does not need as much blood and oxygen supply.
Safety advice
Alcohol
CAUTION
Alcohol should be used with caution while taking Monotrate 20 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
The safety of Monotrate 20 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CONSULT YOUR DOCTOR
Monotrate 20 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
UNSAFE
Monotrate 20 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Monotrate 20 Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
However, talk to your doctor if you have any underlying kidney disease.
However, talk to your doctor if you have any underlying kidney disease.
Liver
SAFE IF PRESCRIBED
Monotrate 20 Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.
What if you forget to take Monotrate Tablet?
If you miss a dose of Monotrate 20 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Monotrate 20 Tablet
₹4.07/Tablet
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Ismo 20 Tablet
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Monit 20 Tablet
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Isonorm 20 Tablet
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Quick tips
- Take Monotrate 20 Tablet exactly as prescribed and at the same time each day to maintain its effectiveness and reduce tolerance.
- Monotrate 20 Tablet may cause dizziness or light-headedness, so avoid driving or operating machinery until you know how it affects you.
- Stand up slowly from sitting or lying positions, as this medicine may cause a drop in blood pressure and dizziness.
- Avoid alcohol while taking Monotrate 20 Tablet, as it may increase dizziness or light-headedness.
- Headache is a common side effect when starting Monotrate 20 Tablet, and it usually improves with continued use; inform your doctor if it becomes severe or persistent.
- Do not take medicines for erectile dysfunction (such as sildenafil or tadalafil) while using Monotrate 20 Tablet, as this combination can cause a dangerous drop in blood pressure.
- Monotrate 20 Tablet is usually used to prevent angina attacks and not for immediate relief; seek urgent medical attention if you develop sudden or severe chest pain.
- Follow the prescribed dosing schedule carefully, as tolerance to nitrates may develop if dosing instructions are not followed properly.
- Maintain heart-healthy lifestyle habits, such as a balanced diet, regular physical activity, weight control, stress reduction, and avoiding smoking.
- Consult your doctor if you experience severe weakness, fainting, confusion, or persistent symptoms while taking Monotrate 20 Tablet.
Fact Box
Chemical Class
Isosorbides
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Nitric Oxide (NO) Donors
Interaction with drugs
Taking Monotrate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Sildenafil with Isosorbide Mononitrate. If Sildenafil is essential, ensure a gap of at least 24 hours after discontinuing Isosorbide Mononitrate. Please consult your
Do not consume Tadalafil with Isosorbide Mononitrate. If Tadalafil is essential, ensure a gap of at least 48 hours between taking Tadalafil and Isosorbide Mononitrate.
Concomitant
Do not consume Sildenafil with Isosorbide Mononitrate. If Sildenafil is essential, ensure a gap of at least 24 hours after discontinuing Isosorbide Mononitrate. Please consult your
Do not consume Sildenafil with Isosorbide Mononitrate. If Sildenafil is essential, ensure a gap of at least 24 hours after discontinuing Isosorbide Mononitrate. Please consult your
Do not consume Sildenafil with Isosorbide Mononitrate. If Sildenafil is essential, ensure a gap of at least 24 hours after discontinuing Isosorbide Mononitrate. Please consult your
User feedback
Patients taking Monotrate 20 Tablet
Twice A Day
80%
Once A Day
20%
What are you using Monotrate Tablet for?
Angina (heart*
77%
Others
23%
*Angina (heart-related chest pain)
How much was the improvement?
Poor
53%
Average
33%
Excellent
13%
What were the side-effects while using Monotrate 20 Tablet?
Headache
40%
Dizziness
20%
Increased hea*
20%
Orthostatic h*
20%
*Increased heart rate, Orthostatic hypotension (sudden lowering of blood pressure on standing)
FAQs
What is Monotrate 20 Tablet and what is it used for?
Monotrate 20 Tablet is a medicine used to help prevent angina, which is chest pain caused by reduced blood flow to the heart. It works by relaxing and widening the blood vessels, allowing blood to flow more easily to the heart and reducing the heart’s workload. This helps prevent episodes of chest pain during daily activities. However, Monotrate 20 Tablet is not intended to relieve sudden angina attacks once they have started. Because the medicine can lower blood pressure, some people may feel dizzy or light-headed, especially when standing up quickly.
Does Monotrate 20 Tablet affect heart rate?
Monotrate 20 Tablet may affect heart rate in some people. Because the medicine lowers blood pressure by widening blood vessels, the body may respond by increasing the heart rate (reflex tachycardia) in some cases. These changes are usually mild, but if you notice a significant change in heart rate or feel unwell after taking the medicine, you should consult your doctor.
How quickly does Monotrate 20 Tablet start working?
Monotrate 20 Tablet may begin working the same day you start taking it, but its main purpose is to prevent angina over time rather than provide immediate symptom relief. The medicine releases its active ingredient slowly to maintain a steady protective effect. Because it works gradually, you may not feel any immediate difference even though it is helping protect your heart.
When should I take Monotrate 20 Tablet?
Monotrate 20 Tablet is usually taken once daily in the morning unless your doctor recommends a different schedule. Taking it at the same time every day helps maintain a consistent effect in the body. Doctors often schedule the dose in a way that allows a daily nitrate-free interval, which helps prevent the body from becoming tolerant to the medicine. If your doctor prescribes it twice daily, the doses are usually spaced several hours apart.
What should I do if I miss a dose of Monotrate 20 Tablet?
If you forget to take a dose of Monotrate 20 Tablet, take it as soon as you remember, as long as it is within about 12 hours of the scheduled time. If more than 12 hours have passed, skip the missed dose and take the next dose at the usual time. Do not take two doses at the same time to make up for a missed one.
What is the most common side effect of Monotrate 20 Tablet?
Headache is one of the most common side effects of Monotrate 20 Tablet. Some people may also experience flushing, dizziness, or symptoms of low blood pressure. These effects occur because the medicine widens blood vessels. Headaches often improve as the body adjusts to the medication. If headaches are severe or persistent, consult your doctor.
Can I stop taking Monotrate 20 Tablet on my own?
You should not stop taking Monotrate 20 Tablet without consulting your doctor. Stopping the medicine suddenly may increase the risk of angina attacks. If you have concerns about side effects or the need for the medication, speak with your doctor before making any changes.
What are the symptoms of an overdose of Monotrate 20 Tablet?
Taking more than the recommended dose of Monotrate 20 Tablet may cause symptoms such as a severe throbbing headache, flushing of the skin, sweating, chills, nausea, vomiting, or a rapid heartbeat. If an overdose is suspected, seek emergency medical help immediately and contact your doctor.
What should I avoid while taking Monotrate 20 Tablet?
While taking Monotrate 20 Tablet, avoid using medicines for erectile dysfunction such as sildenafil, tadalafil, or vardenafil unless your doctor specifically approves them. Combining these medicines can cause a dangerous drop in blood pressure. Alcohol should also be limited because it may increase dizziness or light-headedness. Rise slowly from sitting or lying positions to reduce the risk of fainting.
Does Monotrate 20 Tablet cause sleepiness?
Monotrate 20 Tablet does not usually cause direct sleepiness. However, some people may feel dizzy or tired due to its blood pressure–lowering effect. If you feel faint or unsteady after taking the medicine, avoid driving or operating machinery until you feel better. If these symptoms persist, consult your doctor.
Can Monotrate 20 Tablet affect the kidneys or liver?
Monotrate 20 Tablet is not commonly known to directly harm the kidneys or liver. However, if blood pressure drops too low or if dehydration occurs, kidney function may be affected in some people. Maintaining adequate fluid intake and following your doctor’s advice can help reduce this risk. If you notice reduced urination, repeated dizziness, or unusual symptoms while taking Monotrate 20 Tablet, consult your doctor.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 47.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 744.
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online). Available from:
- Central Drugs Standard Control Organisation. Isosorbide Mononitrate. [Accessed 05 Jul. 2023]. (online). Available from:
- National Health Service. Isosorbide mononitrate and isosorbide dinitrate. [Last Reviewed: 1 Jul. 2021]. [Accessed 05 Jul. 2023]. (online). Available from:
- Isosorbide mononitrate tablet [Prescribing Information]. Dupnitsa, Bulgaria: Balkanpharma - Dupnitsa AD; 2022. [Accessed 05 Jul. 2023]. (online). Available from:
- Isosorbide mononitrate tablet [Prescribing Information]. Castleford, UK: Teva UK Ltd.; 2022. [Accessed 07 Jan. 2026]. (online). Available from:
Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Acme Plaza, Andheri-Kurla Road, Andheri (East), Mumbai, Maharashtra -400059
Country of origin: India
Expires on or after: March, 2028
A licensed vendor partner from your nearest location will deliver Monotrate 20 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: March, 2028
A licensed vendor partner from your nearest location will deliver Monotrate 20 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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MRP₹45 10% OFF
₹40.7
Inclusive of all taxes
10.0 tablets in 1 strip
The price displayed is the MRP (inclusive of applicable taxes). Any additional fee (such as shipping fee, handling and/or platform fee etc.) will be clearly disclosed before you complete your purchase.
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