Metafolate Tablet is a combination of two medicines used in the treatment of polycystic ovarian syndrome (PCOS). It regulates ovulation and menstrual cycles (periods) in PCOS. It enhances the body's response to insulin and maintains hormonal balance. This improves your overall health.
Metafolate Tablet should be taken in the dose and duration as advised by your doctor. It can be taken with or without food, preferably at the same time each day. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
It may cause side effects like taste changes, nausea, diarrhea, vomiting, stomach pain, and loss of appetite. However, these are temporary and usually subside on their own. Please consult your doctor in case these do not resolve or persist for a longer duration.
Before taking Metafolate Tablet, inform your doctor if you have any kidney, liver, or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.
In Treatment of Polycystic ovarian syndrome (PCOS)
Women with Polycystic ovarian syndrome (PCOS) have hormonal imbalance that is responsible for irregular menstrual cycles (periods), excessive hair growth and acne. Metafolate Tablet is a combination medicine that helps in regulating hormonal imbalance as well as periods in females. It helps the body to utilise the hormone insulin and also regulates menstrual cycles. Take it as prescribed by the doctor. Do not skip any doses and follow your doctor’s instructions carefully to get maximum benefit.
Side effects of Metafolate Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Metafolate
Taste change
Dizziness
Stomach pain
Nausea
Diarrhea
Loss of appetite
How to use Metafolate Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metafolate Tablet may be taken with or without food.
How Metafolate Tablet works
Metafolate Tablet contains metformin and myoinositol, which treats polycystic ovarian syndrome (PCOS) in females. Metformin is an antidiabetic medicine which helps regulate hormones in PCOS by balancing insulin levels. This regularizes menstruation and ovulation cycles. Myo-inositol is a naturally occurring messenger which ensures proper binding of insulin to its receptors and regulates the signaling that follows the binding process. Like this, it improves body’s response to insulin, and improves hormone balance.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Metafolate Tablet
Pregnancy
SAFE IF PRESCRIBED
Metafolate Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Metafolate Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving
CONSULT YOUR DOCTOR
It is not known whether Metafolate Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
CAUTION
Metafolate Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed. Use of Metafolate Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
UNSAFE
Metafolate Tablet is unsafe to use in patients with liver disease and should be avoided. Metafolate Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
What if you forget to take Metafolate Tablet?
If you miss a dose of Metafolate Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Metafolate Tablet is a combination of two medicines used for the treatment of polycystic ovarian syndrome (PCOS).
It helps support regular ovulation and menstrual cycles.
An upset stomach with nausea and diarrhea may occur initially. Take it with food to avoid an upset stomach.
Hypoglycemia (low blood sugar level) may occur when taken along with antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source for immediate relief.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
User feedback
Patients taking Metafolate Tablet
Once A Day
53%
Twice A Day
45%
Thrice A Day
2%
What are you using Metafolate Tablet for?
Polycystic ov*
91%
Others
9%
*Polycystic ovarian syndrome (PCOS)
How much was the improvement?
Average
50%
Poor
39%
Excellent
11%
What were the side-effects while using Metafolate Tablet?
No Side Effec*
43%
Nausea
29%
Loss of appet*
14%
Taste change
14%
*No Side Effect, Loss of appetite
How do you take Metafolate Tablet?
With food
83%
With or witho*
17%
*With or without food
Please rate Metafolate Tablet on price
Expensive
56%
Average
44%
FAQs
What is Metafolate Tablet?
Metafolate Tablet is a combination of two medicines: Metformin and Myo Inositol. This medicine is used in the treatment of Polycystic ovarian syndrome (PCOS). Metformin is an antidiabetic medicine which helps to regulate menstrual cycle by improving the insulin sensitivity. This helps in regularizing the menstrual cycles in women. Myo-inositol is safe and effective and acts as natural insulin sensitizer which helps to reduce androgen (male) hormones and restores ovulatory function in females.
What are the possible side effects of Metafolate Tablet?
The use of Metafolate Tablet is associated with common side effects like nausea, altered taste, diarrhea, stomach pain and loss of appetite.
What is polycystic ovarian syndrome (PCOS)?
Polycystic ovarian syndrome is a medical condition seen in women of childbearing age. PCOS causes irregular menstrual cycle (periods), excess levels of androgens (high level of male hormones) and polycystic ovaries (enlarged ovaries with fluid-filled sacs or follicles). Signs and symptoms include raised insulin levels leading to diabetes, irregular periods or absence of periods, weight gain, oily skin or acne, excessive hair growth (hirsutism) usually on the face, chest, back or buttocks and thinning of hair.
Can the use of Metafolate Tablet cause nausea and vomiting?
Yes, the use of Metafolate Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can help prevent nausea. Avoid taking fatty or fried foods along with this medicine. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to a doctor.
When should I take Metafolate Tablet?
It is best to take Metafolate Tablet at your bed time as this will minimize the side effects caused by this medicine.
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References
ScienceDirect. Vitamin D. [Accessed 05 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organization. Metformin+Myo-Inositol [Approval Letter]. [Accessed 28th Sept. 2023] (online) Available from:
Myo-Inositol and Metformin Hydrochloride. Mohali, Punjab: Kabir Lifesciences; [Accessed 20 Jan. 2026] (online). Available from:
Marketer details
Name: Ajanta Pharma Limited
Address: Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India