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MBA, MD Pharmacology
Last updated
29 Nov 2023 | 06:57 PM (IST)

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Product introduction

Metafolate Tablet is a combination of medicines used in the treatment of polycystic ovarian syndrome (PCOS). It regulates ovulation and menstrual cycles (periods) in PCOS. It enhances the body's response to insulin, and maintains hormonal balance. This improves your overall health.


Metafolate Tablet should be taken in the dose and duration as advised by your doctor. It is to be taken with food, preferably at the same time each day. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

It may cause side effects like taste change, nausea, diarrhea, stomach pain, and loss of appetite. However, these are temporary and usually subside on their own. Please consult your doctor in case these do not resolve or persist for a longer duration.

Before taking Metafolate Tablet, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Metafolate Tablet

Benefits of Metafolate Tablet

In Polycystic ovarian syndrome (PCOS)

Women with Polycystic ovarian syndrome (PCOS) have hormonal imbalance that is responsible for irregular menstrual cycles (periods), excessive hair growth and acne. Metafolate Tablet is a combination medicine that helps in regulating hormonal imbalance as well as periods in females. It helps the body to utilise the hormone insulin and also regulates menstrual cycles. Take it as prescribed by the doctor. Do not skip any doses and follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Metafolate Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Metafolate

  • Taste change
  • Nausea
  • Diarrhea
  • Stomach pain
  • Loss of appetite

How to use Metafolate Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metafolate Tablet is to be taken with food.

How Metafolate Tablet works

Metafolate Tablet is a combination of four medicines: Metformin , L-Methyl Folate , Methylcobalamin/Mecobalamin and Myo-Inositol which treat polycystic ovarian syndrome (PCOS) in females. Metformin helps regulate hormones in PCOS by balancing insulin levels. This effect leads to more regular menstruation and ovulation cycles. L-Methyl Folate and Methylcobalamin/Mecobalamin provide essential nutrients. Myo-Inositol ensures proper binding of insulin to its receptors and regulates the signaling that follows the binding process. Like this, it enhances body’s response to insulin, and improves hormone balance.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Metafolate Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Metafolate Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Metafolate Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Metafolate Tablet should be used with caution in patients with kidney disease. Dose adjustment of Metafolate Tablet may be needed. Please consult your doctor.
Use of Metafolate Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Metafolate Tablet should be used with caution in patients with liver disease. Dose adjustment of Metafolate Tablet may be needed. Please consult your doctor.
Metafolate Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

What if you forget to take Metafolate Tablet?

If you miss a dose of Metafolate Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Metafolate Tablet
₹20.1/Tablet
Oosure-M Tablet
Akumentis Healthcare Ltd
₹30.5/tablet
52% costlier

Quick tips

  • Metafolate Tablet is used for the treatment of polycystic ovarian syndrome (PCOS) and diabetes.
  • It helps support regular ovulation and menstrual cycles.
  • An upset stomach with nausea and diarrhea may occur initially. Take it with food to avoid an upset stomach.
  • Hypoglycemia (low blood sugar level) may occur when taken along with antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source for immediate relief.

Fact Box

Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL

Patient concerns

arrow
Multi follicular and irregular periods
Dr. Suman Rao
Obstetrics and Gynaecology
You could have been suffering from polycystic ovarian syndrome . Get your PCOS profile done on the second day of your cycle and then take treatment .
I'm having cyst on left ovary and irregular menses pls suggest me
Dr. Suman Rao
Obstetrics and Gynaecology
You could be having polycystic ovarian syndrome. First get your PCOD profile done on the 2nd day of your cycle and then take treatment
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Drugs.com. Metformin. [Accessed 25 Apr. 2019] (online) Available from:External Link
  2. DailyMed. L-Methyl Calcium floate. [Accessed 25 Apr. 2019] (online) Available from:External Link
  3. Drugs.com. Cyanocobalamin Pregnancy and Breastfeeding Warnings. [Accessed 25 Apr. 2019] (online) Available from:External Link
  4. ScienceDirect. Vitamin D. [Accessed 25 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Ajanta Pharma Ltd
Address: Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Country of origin: India

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Same salt composition:Metformin (500mg), L-Methyl Folate (0.5mg), Methylcobalamin/Mecobalamin (750mcg), Myo-Inositol (550mg)
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