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Meqsel Tablet

rx_imgPrescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Meqsel Tablet is used alone or in combination with other medicines to treat unresectable or metastatic melanoma. An unresectable or metastatic melanoma is an advanced stage of skin cancer where the cancer has either spread to other parts of the body or has become challenging to remove through surgery.

Meqsel Tablet should be taken in the dose and duration as advised by the doctor. The duration of treatment varies on the basis of your response to the treatment. Your doctor may advise regular eye examinations while taking this medicine. You must inform the doctor if you experience eye irritation, blurred vision, eye pain, or other vision changes during your treatment.


The most common side effects of this medicine are rash, diarrhea, and lymphedema (swelling of lymph nodes). It may also cause other side effects like fever, chills, fatigue, rash, nausea, vomiting, and abdominal pain. Consult your doctor if you experience any of these side effects that do not go away or get worse. They may be able to help you with ways of preventing or reducing the effects. 


Before taking Meqsel Tablet, tell your doctor if you have liver or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine, so let your doctor know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during the treatment with this drug is important to avoid pregnancy.


Benefits of Meqsel Tablet

In Treatment of unresectable or metastatic Melanoma

Melanoma is a type of skin cancer that develops in melanocytes, the cells that produce the pigment called melanin. Melanin is the pigment that gives the skin its color. Melanoma is the most deadly and aggressive kind of skin cancer. Meqsel Tablet sticks to the genetic code, called DNA, of the cancer cells and kills them. It also prevents their growth and further spread, which help treat cancer.

Side effects of Meqsel Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Meqsel

  • Rash
  • Diarrhea
  • Lymphedema
  • Fever
  • Chills
  • Nausea
  • Vomiting
  • Abdominal pain
  • Peripheral edema
  • Cough
  • Headache
  • Joint pain
  • Night sweats
  • Decreased appetite
  • Constipation
  • Muscle pain

How to use Meqsel Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Meqsel Tablet is to be taken with food.

How Meqsel Tablet works

Meqsel Tablet works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.

Safety advice

Alcohol
There is no data available. Please consult doctor before consuming the drug.
Pregnancy
CONSULT YOUR DOCTOR
Meqsel Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Meqsel Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Meqsel Tablet may cause side effects which could affect your ability to drive.
Patients should be made aware of potential for fatigue, dizziness, or eye problems that might affect the ability to drive or use machines.
Kidney
There is no data available. Please consult doctor before consuming the drug.
Liver
There is no data available. Please consult doctor before consuming the drug.

What if you forget to take Meqsel Tablet?

If you miss a dose of Meqsel Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Notify your doctor if you develop swelling in your feet, shortness of breath, or a fast heartbeat, as these could be signs of heart-related side effects, which require prompt attention while on this medicine.
  • Tell your doctor if you are allergic to any ingredient of Meqsel Tablet.
  • Tell your doctor if you have or have ever had lung disease or breathing problems; diabetes; bleeding problems or blood clots; colitis (inflammation of the colon); stomach problems; high blood pressure; heart, eye, liver, or kidney disease; or any other medical conditions.
  • Meqsel Tablet may decrease fertility in women. Talk to your doctor about the risks of taking Meqsel Tablet.
  • Unless your doctor tells you otherwise, continue your normal diet.

Fact Box

Chemical Class
Pyridopyrimidines
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
MEK inhibitor

Interaction with drugs

Taking Meqsel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Concurrent use may increase the risk of bleeding.
If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Concurrent use may increase the risk of bleeding.
If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Concurrent use may increase the risk of bleeding.
If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Concurrent use may increase the risk of bleeding.
If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Concurrent use may increase the risk of bleeding.

Patient concerns

if any one detect with melanoma is it sure that he/she gonna die after 5 or 10 year
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
No if melanoma is localized it can be removed by surgery
Last year i had chicken pox in august and after that some black moles are developing. I have one in my calf muscle and i m worried that it may turned out to be melanoma. I m attaching the photo.
Dr. Atul Jain
Dermatology
Melanoma is very rare in IndiaIt's just moleU can visit skin specialist for proper examination and treatment

FAQs

What is Meqsel Tablet used for?

Meqsel Tablet is a targeted cancer medication (MEK inhibitor) used to treat certain types of melanoma (skin cancer), some forms of lung cancer, and specific thyroid cancers. It works by blocking certain proteins that help cancer cells grow. It is usually given to people whose cancer has a specific genetic change (BRAF mutation).

How does Meqsel Tablet help treat cancer?

Meqsel Tablet is a targeted cancer therapy that blocks the MEK1 and MEK2 proteins, which are part of a chain (MAPK/ERK pathway) that helps cancer cells grow. By blocking these proteins, Meqsel Tablet slows down or stops tumor growth, especially in cancers with BRAF V600 mutations.

Can Meqsel Tablet cause serious or life-threatening side effects?

Yes. Though rare, serious side effects of Meqsel Tablet include heart problems (reduced ejection fraction), lung inflammation (ILD/pneumonitis), vision issues (retinal detachment or vein blockage), severe skin reactions (Stevens-Johnson syndrome), liver damage, and blood clots. You should contact your doctor immediately if you notice chest pain, trouble breathing, or vision changes.

Who should not take Meqsel Tablet?

Individuals should not take Meqsel Tablet if they are allergic to trametinib or its ingredients, do not have a BRAF V600 mutation in their cancer, are pregnant or planning pregnancy, or have severe heart or lung conditions.

How should Meqsel Tablet tablets be taken for best results?

You can take Meqsel Tablet once daily on an empty stomach, at least 1 hour before or 2 hours after food. Swallow the medicine whole with water. Try to take it at the same time every day. If you vomit after taking it, do not take another dose and wait for the next scheduled dose.

What precautions should I follow while on Meqsel Tablet treatment?

During Meqsel Tablet cancer therapy, you should have regular heart scans (LVEF monitoring), check liver function every 4 weeks, monitor blood pressure regularly, and watch for signs of infection, fever, or visual changes. Routine check-ups help detect any early signs of complications.

What are the signs I should stop taking Meqsel Tablet and seek medical help?

You should stop taking Meqsel Tablet and get emergency help if you experience high fever, chills, or severe body pain, chest pain, fast heartbeat, or fainting, sudden vision loss or blurry vision, and signs of allergic reaction like swelling, rash, or breathing issues.

Does Meqsel Tablet cure cancer permanently?

Meqsel Tablet is not a cure, but it can shrink tumors, delay cancer progression, and improve survival in patients with specific mutations. Its best results are seen when used with other anti-cancer medicines (like dabrafenib) and started early in treatment. Regular follow-ups and scans are essential.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
  2. Trametinib. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2014 [revised 14 Feb. 2019]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  3. Trametinib [Prescribing Information]. Research Triangle Park, NC: GlaxoSmithKline; 2014. [Accessed 23 Nov. 2023] (online) Available from: External Link
  4. Trametinib [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2022. [Accessed 23 Nov. 2023] (online) Available from: External Link
  5. Trametinib [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2023. [Accessed 23 Nov. 2023] (online) Available from: External Link

Marketer details

Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Country of origin: Switzerland
Expires on or after: January, 2027

A licensed vendor partner from your nearest location will deliver Meqsel Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP54960  4% OFF
52756
Inclusive of all taxes
30.0 tablets in 1 bottle
New GST benefit included in this MRP, may differ from label
Not returnable Read policy
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