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Meprelone 4mg Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 11 Feb 2026 | 12:24 PM (IST)
Meprelone 4mg Tablet is a medicine used to treat a wide variety of medical conditions such as severe allergic conditions, asthma, rheumatic disorder, skin and eye disorders, and systemic lupus erythematosus. It provides relief by preventing the release of substances that cause inflammation.
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Meprelone 4mg Tablet image
Meprelone 4mg Tablet image

Product introduction

Meprelone 4mg Tablet should be taken with or without food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are being treated for. You should always take the amount prescribed. Do not take a larger dose or use it more often. Keep taking it regularly even if you feel well. Some conditions will become worse if you stop using this medicine.


The most common side effects of this medicine include infection, increased blood pressure, acne, mood disroder and decreased potassium level in blood. If these side effects bother you or do not go away, your doctor may suggest ways of preventing or reducing them. The use of this medicine may lower your ability to fight infections so avoid being near people who might pass on infections such as measles, chickenpox, or flu.


Before using this medicine, you should tell your doctor if you have brittle bones (osteoporosis), mood disorders, high blood pressure, or liver disease. Also, tell your doctor if you have diabetes, this medicine may increase blood glucose levels which can cause or worsen diabetes. Many other drugs may affect, or be affected by, this medicine so let your doctor know all other medicines you are using, to make sure it is safe. You should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Meprelone Tablet

Benefits of Meprelone Tablet

Treatment of Allergic conditions
Meprelone 4mg Tablet is used to treat different inflammatory and allergic conditions including arthritis, lupus, psoriasis, ulcerative colitis which affect the skin, blood, eyes, lungs, stomach, and nervous system. It works by lowering your immune system’s response to these conditions thereby reducing symptoms such as swelling, pain, itching and other allergic-type reactions.
This medicine is given orally (by mouth). You should always take it as it has been prescribed for you. Do not stop taking it without your doctor’s advice. This can cause unpleasant withdrawal symptoms. Because this medicine weakens your immune system, you should avoid being near people who are ill or have infections.
Treatment of Systemic lupus erythematosus (SLE)
Systemic lupus erythematosus (SLE) is an autoimmune disease. In this disease, the immune system of the body mistakenly attacks healthy tissue. It can affect the skin, joints, kidneys, brain, and other organs. Meprelone 4mg Tablet prevents the release of substances in the body that cause inflammation. It lowers your immune system’s response and reduces symptoms such as swelling, pain, itching and other allergic-type reactions.
Treatment of Skin disorders
Meprelone 4mg Tablet prevents the release of substances in the body that cause inflammation. It can be used to treat different inflammatory and allergic conditions of the skin such as eczema and psoriasis. It works by lowering your immune system’s response to these conditions thereby relieving symptoms such as swelling, pain, itching and other allergic-type reactions.
Treatment of Eye disorders
Meprelone 4mg Tablet helps relieve symptoms of eye infections such as redness, swelling, itching and watering of eyes. This medicine works by decreasing the production of certain chemicals that cause inflammation of the eyes. This will make it easier for you to go about your daily activities. Use it as prescribed to get the most benefit. If you see no improvement even after a week, talk to your doctor.
Treatment of Rheumatic disorder
Rheumatic disorder is an autoimmune condition where your body’s immune system (which usually fights bacteria and viruses) attacks your body’s own cells. Meprelone 4mg Tablet stops that from happening and can relieve the symptoms of this condition such as pain, swelling, and stiffness in your joints. It can also slow down joint damage, reduce disability, and enable you to be as active for as long as possible. It can take several weeks or months to notice the effect of the medicine. You should continue taking it until your doctor says it is okay to stop using the medicine.

Side effects of Meprelone Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Meprelone
  • Increased risk of infection
  • Fluid overload
  • Growth retardation
  • Skin atrophy
  • Mood changes
  • Posterior subcapsular cataract
  • Impaired healing
  • Decreased potassium level in blood

How to use Meprelone Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Meprelone 4mg Tablet may be taken with or without food.
Avoid Meprelone 4mg Tablet with dietary sodium.

How Meprelone Tablet works

Meprelone 4mg Tablet is a steroid which works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.

Quick tips

  • Meprelone 4mg Tablet helps treat inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems that require either reduction of inflammation or suppression of the immune system.
  • Do not use it more often or for longer than advised by your doctor.
  • Meprelone 4mg Tablet can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.
  • Side effects such as mood changes or stomach problems can happen when you start taking Meprelone 4mg Tablet. Inform your doctor if this bothers you.
  • Do not stop taking Meprelone 4mg Tablet suddenly without talking to your doctor first as it may worsen your symptoms.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Meprelone 4mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Meprelone 4mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Meprelone 4mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

SAFE
Meprelone 4mg Tablet does not usually affect your ability to drive.
Undesirable effects, such as dizziness, vertigo, visual disturbances and fatigue are possible after treatment with Meprelone 4mg Tablet. This may affect your driving ability.
Kidney

Kidney

CAUTION
Meprelone 4mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
However, talk to your doctor if you have any underlying kidney disease.
Liver

Liver

CAUTION
Meprelone 4mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Meprelone with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Cholera Vaccine (Inactivated) (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Methylprednisolone may reduce the efficacy of Cholera Vaccine (Inactivated).
Severe

Clarithromycin (Oral Route)

Your doctor may monitor your potassium levels closely.
Severe

Clarithromycin (Oral Route)

Your doctor may monitor your potassium levels closely.
Severe

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Do not use Methylprednisolone with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If essential, please consult your doctor. Methylprednisolone may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

It is recommended to wait at least 3 months after discontinuing a high dose of Methylprednisolone before taking Purified Vi Polysaccharide Typhoid Vaccine.

Frequently asked questions

Meprelone 4mg Tablet has anti-inflammatory and immunosuppressant properties. It is used to treat conditions like allergic conditions, anaphylaxis, asthma, rheumatoid arthritis and inflammatory skin diseases. It is also helpful in treating autoimmune diseases (these diseases happen when your body’s immune system attacks the body itself and causes damage) and certain eye disorders.
Meprelone 4mg Tablet works by reducing the inflammation which helps in treating many illnesses caused due to active inflammation. In addition to that, it stops the autoimmune reactions which occur when your body's immune system attacks the body itself and causes damage.
Meprelone 4mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Meprelone 4mg Tablet too early, the symptoms may return or worsen.
Meprelone 4mg Tablet effectively treats pain and inflammation. However, its effect may vary from person to person, depending on the condition you are being treated for and also your body weight. Your doctor will prescribe you Meprelone 4mg Tablet in the dose that suits your requirement. Do not alter your dose thinking that a higher dose will provide faster relief. Rather, you may end up having undesirable side effects. Be patient, and follow your doctor’s instructions regarding the use of Meprelone 4mg Tablet. Consult your doctor if you do not see improvement in your condition even after completing the full course of treatment.
If you forget a dose of Meprelone 4mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose on the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Meprelone 4mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Fact Box

Chemical Class

21- hydroxysteroids

Habit Forming

No

Therapeutic Class

HORMONES

Action Class

Glucocorticoids
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Astam Health Care Pvt Ltd
Address: 4697/6, Ajit Bhawan, 21-A, 2nd Floor, Ansari Road,Daryagani, New Delhi - 110002

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Meprelone 4mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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