Megphylle M 400mg/10mg Tablet is a combination medicine used to treat and prevent asthma. It helps in relaxing the muscles of the air passages, thus widening it and making it easier to breathe. It also relieves allergy symptoms like runny nose, sneezing, throat irritation, watery eyes, and congestion or stuffiness.

Megphylle M 400mg/10mg Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, vomiting, stomach pain, headache, insomnia, irritability, increased heart rate, and flu-like symptoms. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may cause sleepiness and dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. You should also tell your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Megphylle M Tablet

Treatment and prevention of Asthma

Benefits of Megphylle M Tablet

In Treatment and prevention of Asthma

Megphylle M 400mg/10mg Tablet can help prevent the onset of an asthma attack if it is taken before exercise or exposure to some “triggers” that include house dust, pollen, pets and cigarette smoke. It also helps the airways in your lungs stay open. It relaxes the muscles of these airways. This makes it easier for air to get in and out. This medicine will allow you to exercise more freely without worrying about getting symptoms such as wheezing, coughing and shortness of breath. It allows you to live your life more freely without worrying so much about things that set off your symptoms.

Side effects of Megphylle M Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Megphylle M

Nausea
Vomiting
Epigastric pain
Tachycardia
Increased respiratory rate
Headache
Abdominal pain
Diarrhea
Rash
Fever
Pharyngitis
Cough
Increased liver enzymes
Influenza
Runny nose
Sinus inflammation
Extrasystoles
Upper respiratory tract infection
Otitis media (infection of ear)

How to use Megphylle M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Megphylle M 400mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Avoid Megphylle M 400mg/10mg Tablet with caffeine and chocolate as well as food containing caffeine and chocolate such as tea leaves, cocoa beans.

How Megphylle M Tablet works

Doxofylline and montelukast. Doxofylline is a bronchodilator. It works by relaxing the muscles in the airways and widens airways. Montelukast is a leukotriene antagonist which blocks the action of leukotriene, a chemical messenger. This reduces inflammation (swelling) in the airways to prevent asthma and relieve symptoms of allergies.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Megphylle M 400mg/10mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Megphylle M 400mg/10mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Megphylle M 400mg/10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Megphylle M 400mg/10mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Megphylle M 400mg/10mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Megphylle M 400mg/10mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Megphylle M 400mg/10mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Megphylle M 400mg/10mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

What if you forget to take Megphylle M Tablet?

If you miss a dose of Megphylle M 400mg/10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Megphylle M 400mg/10mg Tablet

₹14.4/Tablet

Duphill M 400mg/10mg Tablet

Leeford Healthcare Ltd

₹11.7/tablet

19% cheaper

Zeocet DX 400mg/10mg Tablet

Sigma Softgel Formulation

₹18.3/tablet

27% costlier

Doxolin M Tablet

Zydus Cadila

₹9.7/tablet

33% cheaper

Latur D 400mg/10mg Tablet

Remandish Pharma Pvt Ltd

₹12.7/tablet

12% cheaper

Doxofit M 400mg/10mg Tablet

Fitwel Pharmaceuticals Private Limited

₹14.4/tablet

same price

View all substitutes

Quick tips

You have been prescribed Megphylle M 400mg/10mg Tablet for prevention and treatment of asthma.
It is relatively safe, with very few side effects.
Take it at the same time each day, preferably in the evening after food.
Do not use it to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
Notify your doctor if you smoke or have an viral infection. Your dose may need to be adjusted.
Do not stop using it without consulting your doctor, even if you feel better.
You have been prescribed Megphylle M 400mg/10mg Tablet for prevention and treatment of asthma.
It is relatively safe, with very few side effects.
Take it at the same time each day, preferably in the evening after food.
Do not use it to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
Notify your doctor if you smoke or have an viral infection. Your dose may need to be adjusted.
Do not stop using it without consulting your doctor, even if you feel better.

Fact Box

Habit Forming

Therapeutic Class

RESPIRATORY

Patient concerns

Dry scaling Psoriasis (10 years); asthma 3 years.; obesity I have been on folitrax 7.5 mg x 2 once a week for the last 8 years. I also take folvite 50 daily. The breathing difficulty is recent. I am on seroflo inhaler twice a day and tiate once a day. There is no change in the psoriasis but the asthma is getting worse.

Dr. Atul Jain

Dermatology

You should visit md medicine for asthmaNo idea about asthma

Having dry cough not in regular basis sometime in the morning and sometime in the evening for last six months.Please advise some good medicine Thanks

Dr. Vijay Verma

ENT

first get your PFT to rule out asthmait can be seasonal asthma

FAQs

Will a higher than the recommended dosage of Megphylle M 400mg/10mg Tablet be more effective?

No, taking a higher than the recommended dose of Megphylle M 400mg/10mg Tablet will not make it more effective. Further, it can lead to increased side effects. If the symptoms are getting worse, please consult the doctor for re-evaluation.

What are the instructions for the storage and disposal of Megphylle M 400mg/10mg Tablet?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can I stop Megphylle M 400mg/10mg Tablet when my symptoms are relieved?

No, Megphylle M 400mg/10mg Tablet should be continued as advised by the doctor. If you experience any problem due to Megphylle M 400mg/10mg Tablet, inform your doctor.

Can I stop Megphylle M 400mg/10mg Tablet when my symptoms are relieved?

No, Megphylle M 400mg/10mg Tablet should be continued as advised by the doctor. If you experience any problem due to Megphylle M 400mg/10mg Tablet, inform your doctor.

Will a higher than the recommended dosage of Megphylle M 400mg/10mg Tablet be more effective?

What are the instructions for the storage and disposal of Megphylle M 400mg/10mg Tablet?

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

PubChem. Doxofylline. [Accessed 01 Apr. 2019] (online) Available from:
Montelukast sodium. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 04 Jan. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
ScienceDirect. Doxofylline. [Accessed 01 Apr. 2019] (online) Available from:
Montelukast sodium. Whitehouse Station, New Jersey: Merck & Co., Inc.; 1998 [revised Nov. 2014]. [Accessed 01 Apr. 2019] (online) Available from:
Pipeline Pharma. Doxofylline+Montelukast [Product Information]. [Accessed 16 Sep. 2024] (online) Available from:

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The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.