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Mefmark 100mg Syrup

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 09 Apr 2026 | 01:24 PM (IST)
Mefmark 100mg Syrup is a nonsteroidal anti-inflammatory drug (NSAID). It helps relieve pain and inflammation (redness and swelling) in both infants and children. It works by blocking the action of a chemical messenger that is known to cause fever, pain, and inflammation.
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General Information

The content is shown in English
Mefmark 100mg Syrup image
Mefmark 100mg Syrup image

Your child’s medicine at a glance

Follow the prescribed dose, timing, and method when giving Mefmark 100mg Syrup to your child. Give it orally, preferably after food, to reduce the chance of stomach upset. If your child vomits within 30 minutes of taking this medicine, give the same dose again. Do not give more than the recommended dose for faster relief, as this may cause unwanted side effects in your child.


Your child may exhibit side effects like nausea, vomiting, stomach pain, heartburn, and diarrhea after taking this medicine. These side effects are temporary and are likely to subside once your child's body adapts to the medicine. In case they persist or become bothersome for your child, do consult your child's doctor on a priority basis.


Before administering Mefmark 100mg Syrup to your child, inform the doctor if your child is allergic to any medicine or products or has a history of any heart problems, birth defects, liver disease, kidney disease, lung disease, or bleeding disorder. This information is critical for dose alteration and helps in planning your child's overall treatment.

Uses of Mefmark 100mg Syrup in children

  • Pain relief : Mefmark 100mg Syrup helps relieve pain in conditions such as headaches, body aches, muscle pain, toothaches, and minor injuries.

Benefits of Mefmark 100mg Syrup for your child

Pain relief
Pain can occur due to inflammation or injury affecting different parts of the body. Mefmark 100mg Syrup works by blocking chemical messengers that cause pain and inflammation. This helps relieve discomfort in conditions such as headache, toothache, muscle pain, and joint pain. Use it at the lowest effective dose for the shortest duration as advised by your doctor.

Side effects of Mefmark 100mg Syrup in children

Mefmark 100mg Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Mefmark
  • Stomach pain
  • Vomiting
  • Nausea
  • Headache
  • Dizziness

How can I give Mefmark 100mg Syrup to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Mefmark 100mg Syrup may be taken with or without food.

How Mefmark Syrup works

Mefmark 100mg Syrup is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain, and inflammation (redness and swelling).

All substitutes for Mefmark 100mg Syrup

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Mefmark 100mg Syrup should be given to children exactly as prescribed by the doctor, and the dose and frequency should be carefully tracked to avoid overdosing.
  • Maintain a record of your child’s temperature and symptoms while using Mefmark 100mg Syrup, and consult the doctor if there is no improvement.
  • Avoid giving Mefmark 100mg Syrup with other NSAIDs (such as ibuprofen, diclofenac, or aspirin) unless advised by your doctor.
  • Ensure your child drinks plenty of fluids and gets adequate rest, as hydration and sleep support recovery during illness.
  • Inform your doctor if your child has kidney or liver disease before using Mefmark 100mg Syrup.
  • Avoid using Mefmark 100mg Syrup if the child is dehydrated due to vomiting, diarrhea, or excessive heat, and consult the doctor instead.
  • Stop using Mefmark 100mg Syrup and seek urgent medical care if your child develops severe stomach pain, black stools, or vomiting of blood.
  • Stop the medicine and consult the doctor immediately if allergic symptoms such as rash, swelling, or breathing difficulty occur.
  • Do not use Mefmark 100mg Syrup routinely for fever in children unless prescribed by a doctor.
  • Consult your doctor if symptoms persist or if repeated use of Mefmark 100mg Syrup is required.

Safety advice

Kidney

Kidney

CAUTION
Mefmark 100mg Syrup should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Mefmark 100mg Syrup is not recommended in children with severe kidney disease.
Liver

Liver

CAUTION
Mefmark 100mg Syrup should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Mefmark with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

Mefmark 100mg Syrup is a pain-relief medicine that contains mefenamic acid, which belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It is used to relieve mild to moderate pain and inflammation, including menstrual cramps, toothache, muscle pain, joint pain, and other short-term painful conditions. The medicine works by reducing certain chemicals in the body that cause pain and swelling. Mefmark 100mg Syrup helps relieve symptoms but does not treat the underlying cause of pain and should be used only as prescribed by a doctor.
Some people may experience side effects such as stomach pain, acidity, nausea, vomiting, diarrhea, or dizziness while taking Mefmark 100mg Syrup. These effects occur because medicines in this group can irritate the stomach lining. In some cases, people may develop a rash or swelling as a sign of an allergic reaction. Rarely, the medicine may cause stomach bleeding. Seek medical attention immediately if you notice black stools, vomiting blood, severe stomach pain, or swelling.
Mefmark 100mg Syrup may affect the kidneys if taken repeatedly, in high doses, or during dehydration. The risk is higher in older adults and people with kidney disease or high blood pressure. It may affect the liver and increase liver enzymes, but when used as prescribed for a short time, it is generally safe. You must consult your doctor if you notice swelling, reduced urination, or yellowing of the skin or eyes.
Yes, Mefmark 100mg Syrup is usually recommended to be taken with food or after meals. Taking it with food can help reduce stomach irritation, acidity, nausea, or discomfort that may occur when the medicine is taken on an empty stomach. Avoid taking multiple pain medicines together unless your doctor advises it, and consult your doctor if you have a history of stomach ulcers or severe acidity.
The correct dose of Mefmark 100mg Syrup suspension for a child should always be determined by a doctor. The dose depends on the child’s body weight, age, and medical condition. Always follow the dosing schedule prescribed by your child’s doctor to ensure the medicine is safe and effective.
No, you should not increase or decrease the dose of Mefmark 100mg Syrup suspension without consulting a doctor. Increasing the dose may increase the risk of side effects or toxicity, while lowering the dose may reduce the medicine’s effectiveness and cause symptoms to return. If you believe the dose needs adjustment, discuss it with your child’s doctor.
No, the same dose should not be given to all children. The correct dose varies depending on the child’s age, body weight, and medical condition. As children grow, the appropriate dose may also change. Always follow your doctor’s instructions and never give this medicine to another child without medical advice.
After starting Mefmark 100mg Syrup, the medicine may begin reducing pain or fever within a short time, although your child may need to take it for several days depending on the condition. Continue giving the medicine exactly as prescribed by your doctor. If your child does not improve or continues to feel unwell even after completing the recommended course, consult your child’s doctor.
Mefmark 100mg Syrup is generally well tolerated in most children when used in the correct dose. However, seek medical attention immediately if your child develops persistent vomiting, swelling of the body, decreased urination, signs of an allergic reaction such as rash or breathing difficulty, or severe stomach pain that may indicate stomach irritation or ulcers.
Mefmark 100mg Syrup suspension should be stored at room temperature in a dry place, away from direct heat and sunlight. Make sure the bottle is tightly closed after use. Also, keep it out of the sight and reach of children to prevent accidental ingestion.
Mefmark 100mg Syrup suspension should not be used for fever associated with dengue because it may interfere with blood clotting and increase the risk of bleeding. It is also not usually recommended for COVID-19 unless advised by a doctor. In these situations, doctors often recommend other fever-reducing medicines that are considered safer.
If your child is scheduled for a dental extraction or surgical procedure, the doctor may advise stopping Mefmark 100mg Syrup a few days beforehand to reduce the risk of bleeding during the procedure. Always follow the instructions given by your doctor or dentist.
Mefmark 100mg Syrup suspension may interact with some other medicines. Before starting treatment, inform your doctor about all medicines, supplements, or herbal products your child is taking. Always check with your child’s doctor before giving any additional medicine at the same time.

Fact Box

Chemical Class

Aminobenzoic acids

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (fenamates)

References

  1. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989.
  2. Mefenamic Acid [FDA Label]. Atlanta, GA: Sciele Pharma, Inc.; 2018. [Accessed 06 Jan. 2021] (online) Available from:
  3. Mefenamic Acid [Product information]. Sandton, South Africa: Pfizer Laboratories (Pty) Ltd.; 2024. [Accessed 02 Jul. 2025] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Hallmark Chemicals
Address: No-24/6 Ramanagar, Near By Masjid, Nellore, Andhra Pradesh-524002

Vendor Details

Country of origin: India
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