Mefispas Syrup

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 31 Mar 2026 | 02:32 PM (IST)

Mefispas Syrup contains two active ingredients both of which belong to a common class of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs). It helps to lower body temperature (fever) and reduce pain and inflammation (redness and swelling) both in infants and children.

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General Information

Contains

Mefenamic Acid (50mg)+ Paracetamol (125mg)

Marketer

Uni-Pex Pharmaceuticals Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Your child’s medicine at a glance

Adhere to the prescribed dose, time, and way while giving Mefispas Syrup to your child. Give it orally, preferably at a fixed time. It can be given before or after food, but giving it after food helps prevent the chance of developing an upset stomach. If your child vomits within 30 minutes of taking this medicine, give the same dose again. Avoid giving more than the recommended dose for fast relief as that may cause unwanted effects in your child.

Some children develop certain mild side effects like nausea, vomiting, stomach pain, heartburn, and diarrhea after taking this medicine. In case your child develops these side effects, do not worry as these are mostly temporary and resolve on their own. But, if these effects persist or become bothersome for your child, do consult your child’s doctor on a priority basis.

Before giving Mefispas Syrup to your child, do inform the doctor if your child is allergic to any medicine or products or has a history of any heart problems, birth defects, liver disease, kidney disease, lung disease, or bleeding disorder. This information is critical for dose alteration and helps in planning your child's overall treatment.

Uses of Mefispas Syrup in children

Benefits of Mefispas Syrup for your child

Pain relief
Mefispas Syrup is a combination of medicines used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis and muscle aches.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.

Treatment of Fever
Mefispas Syrup is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.

Side effects of Mefispas Syrup in children

Mefispas Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Mefispas

Nausea
Vomiting
Abdominal pain
Heartburn
Diarrhea
Dizziness

How can I give Mefispas Syrup to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Mefispas Syrup may be taken with or without food.

How Mefispas Syrup works

Mefispas Syrup contains Mefenamic acid and paracetamol as its active ingredients. Both these ingredients are non-steroidal anti-inflammatory drugs (NSAIDs). Mefispas Syrup works by blocking the release of certain chemical messengers that cause fever, pain, and inflammation (redness and swelling).

All substitutes for Mefispas Syrup

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Mefispas Syrup is used to reduce pain as well as fever in children and infants.
Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Maintain a log of your child’s temperature. If you do not see any improvement, contact your child’s doctor for advice.
Keep a track of the dose and the frequency in which you have given this medicine to your child. This will help prevent overdosing.
Practice self-care tips like:
1. Give plenty of fluids to your child to ensure proper body hydration (water-levels)
2. Give your child a balanced diet
3. Encourage your child to have optimum sleep since sick children get tired soon and getting plenty of rest helps them recover faster.
Stop the medicine and consult your child’s doctor in case your child exhibits allergic rash or stomach pain soon after taking this medicine.
Mefispas Syrup is used to reduce pain and swelling in various conditions.

Safety advice

Kidney

CAUTION

Mefispas Syrup should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Mefispas Syrup is not recommended in children with severe kidney disease.

Liver

UNSAFE

Mefispas Syrup is unsafe to use in patients with liver disease and should be avoided.
Regular monitoring of the liver by getting liver function tests (LFT) is recommended if your child is taking Mefispas Syrup for a long time.

Frequently asked questions

How much Mefispas Syrup should I give to my child?

Your doctor will prescribe the dose according to your child’s condition and body weight. Stick to the prescribed dosing schedule as that is the best way to ensure safe and complete recovery of your child.

Can I change the dose of Mefispas Syrup for my child by myself according to the severity of illness?

No, it is not recommended to alter the dose of the medicine without consulting a doctor. While an unnecessary increase in dose may lead to toxicity, a sudden lowering of the dosing may cause recurrence of symptoms. So, for best results, speak to your child’s doctor if you feel a change in dose may be needed.

Can all children be given the same dose of Mefispas Syrup?

No. Mefispas Syrup cannot be given to everyone in the same dose. The doctor decides the appropriate dose based on the child’s age and body weight. Since the dose changes so unpredictably, you must never give any dose of this medicine to anyone without consulting a doctor. Follow your doctor’s instructions carefully to get the most benefit.

When will my child feel better?

The doctor may advise you to keep giving Mefispas Syrup to your child for a few days to weeks, depending upon the severity of the illness. You’ll notice that the pain or fever will reduce and your child will start feeling better gradually as the course approaches its end. In case your child continues to feel unwell even after completion of the full prescribed course of the medicine, consult your child’s doctor as soon as possible.

Are there any serious side effects of this medicine for my child?

Mefispas Syrup is well-tolerated by most children. However, if your child experiences any intolerable episodes like persistent vomiting, body swelling, decreased urine frequency, serious allergic reaction, and severe pain due to gastric ulcers, then rush to your doctor on an immediate basis.

How should I store Mefispas Syrup?

Store Mefispas Syrup at room temperature, in a dry place, away from direct heat and light. Avoid leaving medicines within the reach and sight of children.

My child is taking Mefispas Syrup for toothache and now has to undergo an extraction procedure. Should I continue giving Mefispas Syrup?

Withhold Mefispas Syrup from at least 3 to 5 days before a surgical procedure to prevent excessive bleeding. In case of any confusion, it is best to reach out to your child’s doctor.

Can other medicines be given at the same time as Mefispas Syrup?

Mefispas Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Mefispas Syrup. Also, check with your child’s doctor before giving any medicine to your child.

Fact Box

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Uni-Pex Pharmaceuticals Pvt Ltd
Address: 310, W Mall, Mangalam Palace, Sec-3 Rohini, Delhi-85

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Mefispas Syrup

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General Information

Contains

Marketer

Storage

Your child’s medicine at a glance

Uses of Mefispas Syrup in children

Benefits of Mefispas Syrup for your child

Side effects of Mefispas Syrup in children

How can I give Mefispas Syrup to my child?

How Mefispas Syrup works

All substitutes for Mefispas Syrup

Nimucet MF Syrup

Mifee Plus Syrup

Macfast Plus Syrup

Nimucet MF Syrup Orange

Mol M 50mg/125mg Syrup

Quick tips

Safety advice

Kidney

Liver

Frequently asked questions

How much Mefispas Syrup should I give to my child?

Can I change the dose of Mefispas Syrup for my child by myself according to the severity of illness?

Can all children be given the same dose of Mefispas Syrup?

When will my child feel better?

Are there any serious side effects of this medicine for my child?

How should I store Mefispas Syrup?

My child is taking Mefispas Syrup for toothache and now has to undergo an extraction procedure. Should I continue giving Mefispas Syrup?

Can other medicines be given at the same time as Mefispas Syrup?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Complete Blood Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests