

Macfast Plus Syrup
Mefenamic Acid (50mg)+ Paracetamol (125mg)
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Macfast Plus Syrup contains two active ingredients both of which belong to a common class of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs). It helps to lower body temperature (fever) and reduce pain and inflammation (redness and swelling) both in infants and children.
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 13 Mar 2026 | 01:39 PM (IST)
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 13 Mar 2026 | 01:39 PM (IST)
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60 ml Syrup
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Macfast Plus Syrup
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by Macleods Pharmaceuticals Pvt Ltd

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General Information
Contains
Mefenamic Acid (50mg)+ Paracetamol (125mg)
Marketer
Macleods Pharmaceuticals Pvt Ltd
Storage
Store below 30°C
The content is shown in English



Product introduction
Adhere to the prescribed dose, time, and way while giving Macfast Plus Syrup to your child. Give it orally, preferably at a fixed time. It can be given before or after food, but giving it after food helps prevent the chance of developing an upset stomach. If your child vomits within 30 minutes of taking this medicine, give the same dose again. Avoid giving more than the recommended dose for fast relief as that may cause unwanted effects in your child.
Some children develop certain mild side effects like nausea, vomiting, stomach pain, heartburn, and diarrhea after taking this medicine. In case your child develops these side effects, do not worry as these are mostly temporary and resolve on their own. But, if these effects persist or become bothersome for your child, do consult your child’s doctor on a priority basis.
Before giving Macfast Plus Syrup to your child, do inform the doctor if your child is allergic to any medicine or products or has a history of any heart problems, birth defects, liver disease, kidney disease, lung disease, or bleeding disorder. This information is critical for dose alteration and helps in planning your child's overall treatment.
Some children develop certain mild side effects like nausea, vomiting, stomach pain, heartburn, and diarrhea after taking this medicine. In case your child develops these side effects, do not worry as these are mostly temporary and resolve on their own. But, if these effects persist or become bothersome for your child, do consult your child’s doctor on a priority basis.
Before giving Macfast Plus Syrup to your child, do inform the doctor if your child is allergic to any medicine or products or has a history of any heart problems, birth defects, liver disease, kidney disease, lung disease, or bleeding disorder. This information is critical for dose alteration and helps in planning your child's overall treatment.
Uses of Macfast Syrup
Benefits of Macfast Syrup
Pain relief
Macfast Plus Syrup is a combination of medicines used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis and muscle aches.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.
Macfast Plus Syrup is a combination of medicines used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis and muscle aches.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.
Treatment of Fever
Macfast Plus Syrup is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.
Macfast Plus Syrup is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.
Side effects of Macfast Syrup
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Macfast
- Nausea
- Vomiting
- Abdominal pain
- Heartburn
- Diarrhea
- Dizziness
How to use Macfast Syrup
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Macfast Plus Syrup may be taken with or without food.
How Macfast Syrup works
Macfast Plus Syrup contains Mefenamic acid and paracetamol as its active ingredients. Both these ingredients are non-steroidal anti-inflammatory drugs (NSAIDs). Macfast Plus Syrup works by blocking the release of certain chemical messengers that cause fever, pain, and inflammation (redness and swelling).
All substitutes for Macfast Plus Syrup
For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- Macfast Plus Syrup is used to reduce pain as well as fever in children and infants.
- Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
- Maintain a log of your child’s temperature. If you do not see any improvement, contact your child’s doctor for advice.
- Keep a track of the dose and the frequency in which you have given this medicine to your child. This will help prevent overdosing.
- Practice self-care tips like:
- Give plenty of fluids to your child to ensure proper body hydration (water-levels)
- Give your child a balanced diet
- Encourage your child to have optimum sleep since sick children get tired soon and getting plenty of rest helps them recover faster.
- Stop the medicine and consult your child’s doctor in case your child exhibits allergic rash or stomach pain soon after taking this medicine.
- Macfast Plus Syrup is used to reduce pain and swelling in various conditions.
Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking Macfast Plus Syrup.

Pregnancy
CONSULT YOUR DOCTOR
Macfast Plus Syrup is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
UNSAFE
Macfast Plus Syrup is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving
CONSULT YOUR DOCTOR
It is not known whether Macfast Plus Syrup alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney
CAUTION
Macfast Plus Syrup should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Macfast Plus Syrup is not recommended in children with severe kidney disease.
Use of Macfast Plus Syrup is not recommended in children with severe kidney disease.

Liver
UNSAFE
Macfast Plus Syrup is unsafe to use in patients with liver disease and should be avoided.
Regular monitoring of the liver by getting liver function tests (LFT) is recommended if your child is taking Macfast Plus Syrup for a long time.
Regular monitoring of the liver by getting liver function tests (LFT) is recommended if your child is taking Macfast Plus Syrup for a long time.
Frequently asked questions
Your doctor will prescribe the dose according to your child’s condition and body weight. Stick to the prescribed dosing schedule as that is the best way to ensure safe and complete recovery of your child.
No, it is not recommended to alter the dose of the medicine without consulting a doctor. While an unnecessary increase in dose may lead to toxicity, a sudden lowering of the dosing may cause recurrence of symptoms. So, for best results, speak to your child’s doctor if you feel a change in dose may be needed.
No. Macfast Plus Syrup cannot be given to everyone in the same dose. The doctor decides the appropriate dose based on the child’s age and body weight. Since the dose changes so unpredictably, you must never give any dose of this medicine to anyone without consulting a doctor. Follow your doctor’s instructions carefully to get the most benefit.
The doctor may advise you to keep giving Macfast Plus Syrup to your child for a few days to weeks, depending upon the severity of the illness. You’ll notice that the pain or fever will reduce and your child will start feeling better gradually as the course approaches its end. In case your child continues to feel unwell even after completion of the full prescribed course of the medicine, consult your child’s doctor as soon as possible.
Macfast Plus Syrup is well-tolerated by most children. However, if your child experiences any intolerable episodes like persistent vomiting, body swelling, decreased urine frequency, serious allergic reaction, and severe pain due to gastric ulcers, then rush to your doctor on an immediate basis.
Store Macfast Plus Syrup at room temperature, in a dry place, away from direct heat and light. Avoid leaving medicines within the reach and sight of children.
Withhold Macfast Plus Syrup from at least 3 to 5 days before a surgical procedure to prevent excessive bleeding. In case of any confusion, it is best to reach out to your child’s doctor.
Macfast Plus Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Macfast Plus Syrup. Also, check with your child’s doctor before giving any medicine to your child.
Fact Box
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Related lab tests
References
- Mefenamic Acid [FDA Label]. 2008. [Accessed 20 Jan. 2021] (online) Available from:
- University of Michigan: C.S. Mott Children’s Hospital. Mefenamic acid. [Accessed 20 Jan. 2020] (online) Available from:
- Dewan P, Gupta P. 50 Years Ago in The Journal of Pediatrics: Mefenamic Acid: An Antipyretic for Use in Children. J Pediatr. 2018;198:66. [Accessed 20 Jan. 2020] (online) Available from:
- Royal College of Paediatrics and Child Health. Medicines for Children - information for parents and carers. [Accessed 26 Dec. 2020] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Macfast Plus Syrup. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Macfast Plus Syrup. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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