Mefex 250mg Tablet is an antiparasitic medicine, used for the treatment of malaria. It works by killing the malaria-causing parasite and stops the infection from spreading.

Mefex 250mg Tablet should be used in the dose and duration as advised by your doctor. Take it with food to decrease the risk of stomach upset. Do not skip any doses and finish the full course of treatment even if you feel better.

Some people may have stomach pain, abnormal dreams, chills, depression, and diarrhea, as side effects of this medicine. Please consult your doctor if these side effects persist for a longer duration. Inform your doctor if you ever had fits (seizures) or any problems with your kidney, heart, or liver.

Uses of Mefex Tablet

Malaria

Benefits of Mefex Tablet

In Malaria

Mefex 250mg Tablet is an antimalarial medicine and is used to treat malaria, a serious or life-threatening illness that is spread by a parasite that enters the human body by the bite of infected mosquitoes. It kills the infection-causing parasite and stops the further spread of the infection. Take it only as prescribed and refrain from taking any other medicines along with this medicine (unless advised by the doctor) as they may affect the absorption of this medicine. Do not use this medicine for treating any other condition without consulting your doctor.

Side effects of Mefex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mefex

Abdominal pain
Abnormal dreams
Anxiety
Chills
Depression
Diarrhea
Dizziness
Fever
Headache
Atrial arrhythmias (altered heart rate)
Insomnia (difficulty in sleeping)
Itching
Loss of appetite
Muscle pain
Nausea
Rash
Ringing in ear
Vertigo
Visual impairment
Vomiting
Fatigue

How to use Mefex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mefex 250mg Tablet is to be taken with food.

How Mefex Tablet works

Mefex 250mg Tablet is an antiparasitic medication which treats malaria. It works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Mefex 250mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Mefex 250mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Mefex 250mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Mefex 250mg Tablet may cause side effects which could affect your ability to drive.
Mefex 250mg Tablet can cause dizziness, loss of balance and mental problems and this may affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Mefex 250mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Mefex 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Mefex 250mg Tablet may be needed. Please consult your doctor.
Use of Mefex 250mg Tablet is not recommended in patients with severe liver disease.

What if you forget to take Mefex Tablet?

If you miss a dose of Mefex 250mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Mefex 250mg Tablet

₹38.83/Tablet

Meflotas Tablet

Intas Pharmaceuticals Ltd

₹53/tablet

36% costlier

Mefque 250mg Tablet

Zydus Cadila

₹50.5/tablet

30% costlier

Mefloc 250mg Tablet

Aristo Pharmaceuticals Pvt Ltd

₹48/tablet

24% costlier

Larium 250mg Tablet

Roche Products India Pvt Ltd

₹1.45/tablet

96% cheaper

Mefliam Tablet

Cipla Ltd

₹47.67/tablet

23% costlier

View all substitutes

Quick tips

Mefex 250mg Tablet should be taken with food to prevent a stomach upset.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Tips to reduce the chance of being bitten by mosquitoes:
- Wear light-colored and covered clothing when you are outside after sunset.
- Use insect repellent creams or sprays on parts of your body not covered by clothing.
- Spray to kill any mosquitoes that may have entered rooms in spite of screening.
It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Inform your doctor if you have kidney liver or heart disease.

Fact Box

Chemical Class

4-Quinolinemethanol derivative

Habit Forming

Therapeutic Class

ANTI MALARIALS

Action Class

Antimalarial- others

Interaction with drugs

Taking Mefex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Rifampicin (Injection Route) Severe

Rifampicin may reduce blood levels of Mefloquine. Do not consume Mefloquine with Rifampicin. It may result in treatment failure. Please consult your doctor.

Rifampicin (Oral Route) Severe

Rifampicin may reduce blood levels of Mefloquine. Do not consume Mefloquine with Rifampicin. It may result in treatment failure. Please consult your doctor.

Ritonavir (Oral Route) Moderate

Mefloquine may reduce blood levels of active form of Ritonavir. Your doctor may monitor the effects of Ritonavir along with your overall treatment and adjust the doses as per the ... More

Paliperidone (Oral Route) Moderate

Concurrent use may increase the risk of disturbance in the heart rhythm. If concurrent use is essential, your doctor may monitor your electrocardiogram (ECG) regularly.

Quinine (Oral Route) Moderate

Concurrent use may cause seizures and disturbances in heart rhythm. To take Mefloquine, ensure a gap of at least 12 hours after taking Quinine. Factors such as old age, chronic he... More

View all drug interactions

Patient concerns

Which medicine use for Malaria? What is eating in Malaria?

Dr. Saurav Arora

Homeopathy

The medicine depends upon symptoms and stage of disease

Suffering from maleria since 10 days please give me prescription

Dr. Pushkar Mani

Physician

how do u know u have malariaand which type malaria u have

I have fever since last four days, I was prescribed zifi 200 and zerodol p by my doctor, but I started getting rashes, reactions, so the doctor stopped the meds, and said to have crocin only, now fourth day is over, fever comes down after having crocin then comes back again. Body ache, and headache is there, fever reaches 103, 103.8 easily every morning, have pain in my eyes also. Had zathrin 250 in the morning and at night today with crocin, my doctor suggested it on phone. What do I have? And why am I not getting better? What medication should I take?

Dr. Pushkar Mani

Physician

do malaria card test & widal

FAQs

Who should not use Mefex 250mg Tablet?

Use of Mefex 250mg Tablet should be avoided in patients who are allergic to Mefex 250mg Tablet or any of its components. However, if you are not aware of any allergy or if you are using Mefex 250mg Tablet for the first time, consult your doctor.

What should I tell my doctor before starting treatment with Mefex 250mg Tablet?

Before starting treatment with Mefex 250mg Tablet, inform your doctor if you have any other health conditions like kidney- or heart-related problems. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Also, let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are pregnant or breastfeeding.

Is Mefex 250mg Tablet safe?

Mefex 250mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

What if I forget to take a dose of Mefex 250mg Tablet?

If you forget a dose of Mefex 250mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Can I stop taking Mefex 250mg Tablet when I feel better?

No, do not stop taking Mefex 250mg Tablet without consulting your doctor even if you are feeling better. Your symptoms may improve before the infection is completely cured. Therefore, for better and complete treatment, it is advised to continue your treatment for the prescribed duration.

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Related lab tests

Malarial Falciparum & Vivax Antigen

Malarial Parasite Identification

Peripheral Smear Examination

Peripheral Smear for Malaria

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Vinetz JM, Clain J, Bounkeua V, et al. Chemotherapy of Malaria. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1408-409.
Rosenthal PJ. Antiprotozoal Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 906-907.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 855-57.
Medscape. Mefloquine. [Accessed 30 Mar. 2019] (online) Available from:
Center for Global Health. Mefloquine. [Accessed 30 Mar. 2019] (online) Available from:
Mefloquine. Nutley, New Jersey: Roche Laboratories. [Accessed 30 Mar. 2019] (online) Available from:

Marketer details

Name: Alkem Laboratories Ltd

Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.