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Mefcure Plus Syrup contains two active ingredients both of which belong to a common class of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs). It helps to lower body temperature (fever) and reduce pain and inflammation (redness and swelling) both in infants and children.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 21 Sep 2025 | 05:35 PM (IST)
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Mefcure Plus Syrup image
Mefcure Plus Syrup image

Product introduction

Adhere to the prescribed dose, time, and way while giving Mefcure Plus Syrup to your child. Give it orally, preferably at a fixed time. It can be given before or after food, but giving it after food helps prevent the chance of developing an upset stomach. If your child vomits within 30 minutes of taking this medicine, give the same dose again. Avoid giving more than the recommended dose for fast relief as that may cause unwanted effects in your child.

Some children develop certain mild side effects like nausea, vomiting, stomach pain, heartburn, and diarrhea after taking this medicine. In case your child develops these side effects, do not worry as these are mostly temporary and resolve on their own. But, if these effects persist or become bothersome for your child, do consult your child’s doctor on a priority basis.

Before giving Mefcure Plus Syrup to your child, do inform the doctor if your child is allergic to any medicine or products or has a history of any heart problems, birth defects, liver disease, kidney disease, lung disease, or bleeding disorder. This information is critical for dose alteration and helps in planning your child's overall treatment.

Uses of Mefcure Plus Syrup

Benefits of Mefcure Plus Syrup

Pain relief
Mefcure Plus Syrup is a combination of medicines used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis and muscle aches.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.
Treatment of Fever
Mefcure Plus Syrup is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.

Side effects of Mefcure Plus Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mefcure Plus
  • Nausea
  • Vomiting
  • Abdominal pain
  • Heartburn
  • Diarrhea
  • Dizziness

How to use Mefcure Plus Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Mefcure Plus Syrup may be taken with or without food, but it is better to take it at a fixed time.

How Mefcure Plus Syrup works

Mefcure Plus Syrup contains Mefenamic acid and paracetamol as its active ingredients. Both these ingredients are non-steroidal anti-inflammatory drugs (NSAIDs). Mefcure Plus Syrup works by blocking the release of certain chemical messengers that cause fever, pain, and inflammation (redness and swelling).

Quick tips

  • Mefcure Plus Syrup is used to reduce pain as well as fever in children and infants.
  • Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first. 
  • Maintain a log of your child’s temperature. If you do not see any improvement, contact your child’s doctor for advice.
  • Keep a track of the dose and the frequency in which you have given this medicine to your child. This will help prevent overdosing.
  • Practice self-care tips like:
    1. Give plenty of fluids to your child to ensure proper body hydration (water-levels)
    2. Give your child a balanced diet
    3. Encourage your child to have optimum sleep since sick children get tired soon and getting plenty of rest helps them recover faster.
  • Stop the medicine and consult your child’s doctor in case your child exhibits allergic rash or stomach pain soon after taking this medicine.
  • Mefcure Plus Syrup is used to reduce pain and swelling in various conditions.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Mefcure Plus Syrup.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Mefcure Plus Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Mefcure Plus Syrup is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving

Driving

UNSAFE
Mefcure Plus Syrup may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Mefcure Plus Syrup should be used with caution in patients with kidney disease. Dose adjustment of Mefcure Plus Syrup may be needed. Please consult your doctor.
Use of Mefcure Plus Syrup is not recommended in children with severe kidney disease.
Liver

Liver

SAFE IF PRESCRIBED
Mefcure Plus Syrup is safe to use in patients with liver disease. No dose adjustment of Mefcure Plus Syrup is recommended.
Regular monitoring of the liver by getting liver function tests (LFT) is recommended if your child is taking Mefcure Plus Syrup for a long time.

Frequently asked questions

Your doctor will prescribe the dose according to your child’s condition and body weight. Stick to the prescribed dosing schedule as that is the best way to ensure safe and complete recovery of your child.
No, it is not recommended to alter the dose of the medicine without consulting a doctor. While an unnecessary increase in dose may lead to toxicity, a sudden lowering of the dosing may cause recurrence of symptoms. So, for best results, speak to your child’s doctor if you feel a change in dose may be needed.
No. Mefcure Plus Syrup cannot be given to everyone in the same dose. The doctor decides the appropriate dose based on the child’s age and body weight. Since the dose changes so unpredictably, you must never give any dose of this medicine to anyone without consulting a doctor. Follow your doctor’s instructions carefully to get the most benefit.
The doctor may advise you to keep giving Mefcure Plus Syrup to your child for a few days to weeks, depending upon the severity of the illness. You’ll notice that the pain or fever will reduce and your child will start feeling better gradually as the course approaches its end. In case your child continues to feel unwell even after completion of the full prescribed course of the medicine, consult your child’s doctor as soon as possible.
Mefcure Plus Syrup is well-tolerated by most children. However, if your child experiences any intolerable episodes like persistent vomiting, body swelling, decreased urine frequency, serious allergic reaction, and severe pain due to gastric ulcers, then rush to your doctor on an immediate basis.
Store Mefcure Plus Syrup at room temperature, in a dry place, away from direct heat and light. Avoid leaving medicines within the reach and sight of children.
Withhold Mefcure Plus Syrup from at least 3 to 5 days before a surgical procedure to prevent excessive bleeding. In case of any confusion, it is best to reach out to your child’s doctor.
Mefcure Plus Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Mefcure Plus Syrup. Also, check with your child’s doctor before giving any medicine to your child.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zerico Lifesciences Pvt Ltd
Address: ZERICO LIFESCIENCES PVT LTD, 8,SOLITAIRE II,POONAM GARDEN, MIRA ROAD EAST,MUMBAI. , MAHARASTRA., PIN 401107.

Vendor Details

Country of origin: India
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