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Mefan 500mg Tablet

Mefenamic Acid (500mg)

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Mefan 500mg Tablet is used in the treatment of moderate to severe pain conditions like menstrual pain, headache, muscle pain, joint pain, or dental pain. It effectively alleviates pain and inflammation.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 06 Oct 2026 | 01:01 AM (IST)

₹26.4 MRP ₹29.069% off

(Inclusive of applicable taxes)

Gurgaon

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General Information

Contains

Mefenamic Acid (500mg)

Marketer

Tzana Pharmaceuticals Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Mefan 500mg Tablet should be taken with food. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.

The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, you should let your doctor know if you have asthma, have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.

Uses of Mefan Tablet

Pain relief

Benefits of Mefan Tablet

Pain relief
Mefan 500mg Tablet is a common painkiller used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis and muscle aches.

Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.

Side effects of Mefan Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mefan

Abdominal pain
Constipation
Flatulence
Bleeding
Heartburn
Vomiting
Abnormal renal function tests
Anemia (low number of red blood cells)
Edema (swelling)
Increased liver enzymes
Diarrhea
Indigestion
Dizziness

How to use Mefan Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mefan 500mg Tablet should be taken with or after food.

How Mefan Tablet works

Mefan 500mg Tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

All substitutes for Mefan 500mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

It should be taken with food or milk to avoid getting an upset stomach.
It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
Mefan 500mg Tablet can raise your risk of blood clots, heart attack, or a stroke.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Inform your doctor if you have ever been diagnosed with kidney or liver problems.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Mefan 500mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Mefan 500mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Mefan 500mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Mefan 500mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Mefan 500mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Mefan 500mg Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Mefan 500mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Mefan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

Is mefenamic acid an antibiotic/ contain codeine?

No. Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat mild to moderate pain conditions and fever. It not an antibiotic and does not contain codeine

Is Mefan 500mg Tablet a painkiller?

Yes. Mefan 500mg Tablet is mild to moderate painkiller drug

Is Mefan 500mg Tablet safe?

Mefan 500mg Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Is Mefan 500mg Tablet good for toothache/ for back pain/ headache?

Yes, Mefan 500mg Tablet can be used to relieve dental pain, back pain and headache

Does Mefan 500mg Tablet stop periods/ stop bleeding?

Mefan 500mg Tablet is used for relieving pain that happens before or during a menstrual period. It does not stop periods or bleeding. Always consult your doctor regarding its use

Can I take mefenamic acid with naproxen/ paracetamol/ ibuprofen/ metronidazole/ withtramadol/ with tranexamic acid/ with sertraline/ amoxicillin?

Mefenamic acid may interact with the drugs mentioned above. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be require

Does Mefan 500mg Tablet make you drowsy?

Mefan 500mg Tablet has a rare side effect of causing drowsiness. Always consult your doctor, if you experience such side effects.

Fact Box

Chemical Class

Aminobenzoic acids

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (fenamates)

References

Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 854-55.
ScienceDirect. Mefenamic Acid. [Accessed 02 Apr. 2019] (online) Available from:
Mefenamic Acid. 2008 [revised Mar. 2007]. [Accessed 02 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Tzana Pharmaceuticals Pvt Ltd
Address: Singasandra, Bangalore - 560068

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

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Pain Analgesics

Anti Rheumatics Non Steroidal Systemic

Mefan 500mg Tablet

Mefan 500mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Mefan Tablet

Benefits of Mefan Tablet

Side effects of Mefan Tablet

How to use Mefan Tablet

How Mefan Tablet works

All substitutes for Mefan 500mg Tablet

Meftal 500 Tablet

Mef 500mg Tablet

Mef Plus 500mg Tablet

Mefacid 500mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tacrolimus (Oral Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Frequently asked questions

Is mefenamic acid an antibiotic/ contain codeine?

Is Mefan 500mg Tablet a painkiller?

Is Mefan 500mg Tablet safe?

Is Mefan 500mg Tablet good for toothache/ for back pain/ headache?

Does Mefan 500mg Tablet stop periods/ stop bleeding?

Can I take mefenamic acid with naproxen/ paracetamol/ ibuprofen/ metronidazole/ withtramadol/ with tranexamic acid/ with sertraline/ amoxicillin?

Does Mefan 500mg Tablet make you drowsy?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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