
Mefalth 500mg Tablet
Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 19 Sep 2025 | 03:31 PM (IST)
Mefalth 500mg Tablet is used in the treatment of moderate to severe pain conditions like menstrual pain, headache, muscle pain, joint pain, or dental pain. It effectively alleviates pain and inflammation.
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General Information
Contains
Mefenamic Acid (500mg)
Marketer
Orchid Chemicals & Pharmaceuticals Ltd
Storage
Store below 30°C
The content is shown in English



Product introduction
Mefalth 500mg Tablet should be taken with food. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.
The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have asthma, have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.
The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have asthma, have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.
Uses of Mefalth Tablet
Benefits of Mefalth Tablet
Pain relief
Mefalth 500mg Tablet is a common painkiller used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis and muscle aches.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.
Mefalth 500mg Tablet is a common painkiller used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis and muscle aches.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.
Side effects of Mefalth Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mefalth
- Vomiting
- Stomach pain
- Nausea
- Headache
- Dizziness
How to use Mefalth Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mefalth 500mg Tablet is to be taken with food.
How Mefalth Tablet works
Mefalth 500mg Tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).
All substitutes for Mefalth 500mg Tablet
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- It should be taken with food or milk to avoid getting an upset stomach.
- It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
- Mefalth 500mg Tablet can raise your risk of blood clots, heart attack, or a stroke.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Mefalth 500mg Tablet.

Pregnancy
CONSULT YOUR DOCTOR
Mefalth 500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
SAFE IF PRESCRIBED
Mefalth 500mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving
UNSAFE
Mefalth 500mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
CAUTION
Mefalth 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Mefalth 500mg Tablet may be needed. Please consult your doctor.
Use of Mefalth 500mg Tablet is not recommended in patients with severe kidney disease.
Use of Mefalth 500mg Tablet is not recommended in patients with severe kidney disease.

Liver
CAUTION
Mefalth 500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Mefalth 500mg Tablet may be needed. Please consult your doctor.
Interaction with drugs
Taking Mefalth with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Tacrolimus (Oral Route)
If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Frequently asked questions
No. Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat mild to moderate pain conditions and fever. It not an antibiotic and does not contain codeine
Yes. Mefalth 500mg Tablet is mild to moderate painkiller drug
Mefalth 500mg Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Yes, Mefalth 500mg Tablet can be used to relieve dental pain, back pain and headache
Mefalth 500mg Tablet is used for relieving pain that happens before or during a menstrual period. It does not stop periods or bleeding. Always consult your doctor regarding its use
Mefenamic acid may interact with the drugs mentioned above. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be require
Mefalth 500mg Tablet has a rare side effect of causing drowsiness. Always consult your doctor, if you experience such side effects.
Fact Box
Chemical Class
Aminobenzoic Acids Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
NSAID's- Non-Selective COX 1&2 Inhibitors (fenamates)
References
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 854-55.
- ScienceDirect. Mefenamic Acid. [Accessed 02 Apr. 2019] (online) Available from:
- Mefenamic Acid. 2008 [revised Mar. 2007]. [Accessed 02 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Orchid Chemicals & Pharmaceuticals Ltd
Address: Orchid Towers', #313, Valluvar Kottam High Road, Nungambakkam, Chennai - 600 034, Tamil Nadu, India
Address: Orchid Towers', #313, Valluvar Kottam High Road, Nungambakkam, Chennai - 600 034, Tamil Nadu, India
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
Why we need a prescription?
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Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
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