Mefadol Plus Tablet

Tranexamic Acid (500mg)+ Mefenamic Acid (250mg)

Genuine

Authenticity Assured

Prescription

required

Mefadol Plus Tablet is a combination medicine used to treat heavy menstrual bleeding and menstrual pain. It prevents the breakdown of blood clots to control excessive bleeding during periods. It also blocks the production of certain chemical messengers that cause pain and inflammation.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)

Save 13% more with alternative

₹150

₹164.06

9% off

Get for

₹128

on orders above ₹1200

Use Code 1MGNEWPLUS

Get for

₹138

on orders above ₹300

Use Code 1MGNEW

1/2

Welcome Gift | For First Order

15% EXTRA OFF

10 tablets

Get by Tomorrow

Gurgaon

Pay 13% less with a generic alternative with same composition

Contains same composition

Currently viewing

Mefadol Plus Tablet

strip of 10 tablets

₹12.8 per tablet

₹150

~~₹164.06~~

9% off

₹128

order for

₹1200

Get by Tomorrow

by Cista Medicorp

13% lower price

Evetra MF 500 mg/250 mg Tablet

strip of 6 tablets

₹11.17 per tablet

₹78.8

~~₹86.34~~

9% off

₹67

order for

₹1200

Get by Tomorrow

by Cadila Pharmaceuticals Ltd

Save more with additional offers

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Get cashback up to ₹500

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Get upto Rs.150 Cashback

General Information

Contains

Tranexamic Acid (500mg)+ Mefenamic Acid (250mg)

Marketer

Cista Medicorp

Storage

Store below 30°C

The content is shown in English

Product introduction

You can take Mefadol Plus Tablet at any time of day, with food, but it is best to take it at the same time each day. It should be taken on first day of the periods to get the most benefit. Keep taking it for as long as advised by your doctor. Take this medicine in the dose and duration advised by the doctor and if you have missed a dose, take it as soon as you remember. Remember to finish the full course of treatment even if you feel better. Inform your doctor if you do not observe any change in periods even after 3 consecutive periods.

The most common side effects of this medicine include nausea, stomach pain, headache, nasal congestion, sinus pain, sinus inflammation, rash, tiredness, and musculoskeletal (bone, muscle or joint) pain. It may also cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help to prevent dehydration. It is advised to consult with your doctor if you do not notice any changes in periods after 3 consecutive periods.

Before taking it, let your doctor know if you have any kidney problems or vaginal bleeding disorder. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking. You might be asked for eye check-ups while taking this medicine. It is advised to avoid alcohol while taking this medicine.

Uses of Mefadol Plus Tablet

Treatment of Menstrual pain
Treatment of Heavy menstrual bleeding

Benefits of Mefadol Plus Tablet

Treatment of Menstrual pain
Mefadol Plus Tablet relieves the pain due to muscle cramps during menstrual cycles (periods). It blocks the pain signals, relaxes the muscles and prevents sudden contractions (spasms) of muscles. This treats your pain and discomfort. You may also use a heating pad, take a hot water shower, avoid stress and try mild exercise for easing out the pain.

Treatment of Heavy menstrual bleeding
Heavy menstrual bleeding is definitely a concern for every woman. Mefadol Plus Tablet is a combination of medicine that helps treat heavy menstrual bleeding. It helps the lining of the uterus or womb to clot during periods and thus reduces heavy bleeding. It is advisable to use the medicine as prescribed for it to be effective. Also, you can do yoga or meditation to reduce stress and divert your mind during those days.

Side effects of Mefadol Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mefadol Plus

Nausea
Vomiting
Heartburn
Indigestion
Diarrhea
Loss of appetite
Nasal congestion (stuffy nose)
Headache
Tiredness
Musculoskeletal (bone, muscle or joint) pain
Anemia (low number of red blood cells)
Stomach pain
Sinus pain
Sinus inflammation

How to use Mefadol Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mefadol Plus Tablet should be taken with or after food.

How Mefadol Plus Tablet works

Mefadol Plus Tablet is a combination of two medicines: Tranexamic Acid and Mefenamic Acid. Tranexamic Acid is an anti-fibrinolytic. It works by preventing the breakdown of blood clots to control excessive bleeding during periods. Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) which blocks the production of certain chemical messengers (prostaglandins) that cause pain and inflammation (redness and swelling).

All substitutes for Mefadol Plus Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Mefadol Plus Tablet helps relieve menstrual pain and abnormally heavy menstrual bleeding.
Your doctor will prescribe the lowest effective dose for the shortest possible time necessary to relieve your symptoms.
Take it with food to avoid an upset stomach.
Take it on the first day of a heavy period. Taking it before or after will not have any benefit.
Inform your doctor if there is no improvement in your bleeding after using this medicine for three consecutive menstrual periods.
Inform your doctor if you have a history of kidney or liver disease.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Mefadol Plus Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Mefadol Plus Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Mefadol Plus Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Mefadol Plus Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Mefadol Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Mefadol Plus Tablet is not recommended in patients with severe kidney disease.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Mefadol Plus Tablet in patients with liver disease.

Frequently asked questions

What is Mefadol Plus Tablet?

Mefadol Plus Tablet is a combination of two medicines: Tranexamic Acid and Mefenamic Acid. This medication is used to treat pain and is used to treat heavy bleeding during menstrual cycle (monthly periods) in women.

Are there any specific contraindications associated with the use of Mefadol Plus Tablet?

Yes, it is considered to be harmful for patients with severe kidney failure, active intravascular clotting (obstruction in the blood flow due to blood clots), and color vision disorders.

What is the recommended storage condition for Mefadol Plus Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

Therapeutic Class

BLOOD RELATED

References

Want to know more

We provide you with authentic, trustworthy and relevant information

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cista Medicorp
Address: 396, kamath Industrial Estate, Prabhadevi, Mumbai - 400025

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Mefadol Plus Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Mefadol Plus Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Mefadol Plus Tablet

Benefits of Mefadol Plus Tablet

Side effects of Mefadol Plus Tablet

How to use Mefadol Plus Tablet

How Mefadol Plus Tablet works

All substitutes for Mefadol Plus Tablet

Tenacid MF Tablet

Redotrex MF 500mg/250mg Tablet

Pause-MF Tablet

Trapic MF Tablet

Texakind-MF Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Mefadol Plus Tablet?

Are there any specific contraindications associated with the use of Mefadol Plus Tablet?

What is the recommended storage condition for Mefadol Plus Tablet?

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests