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Matulon Plus Tablet SR is a combination of two medicines used in the treatment of polycystic ovarian syndrome (PCOS). It regulates ovulation and menstrual cycles (periods) in PCOS. It enhances the body's response to insulin and maintains hormonal balance. This improves your overall health.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 20 Jan 2026 | 12:08 PM (IST)
₹181 MRP ₹205.3112% off 
 
 
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Matulon Plus Tablet SR is currently sold out
Same composition alternative:
MyoCyst-M Tablet SR
₹296₹321.17
Available alternative from Mankind
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Matulon Plus Tablet SR
Matulon Plus Tablet SR
strip of 10 tablet sr
₹181
₹205.31
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Same composition
MyoCyst-M Tablet SR
MyoCyst-M Tablet SR
strip of 10 tablet sr
by Mankind Pharma Ltd
Get by 11pm
₹296
₹25.2 per unit

₹252

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₹1200
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Matulon Plus Tablet SR image
Matulon Plus Tablet SR image
Matulon Plus Tablet SR image
Matulon Plus Tablet SR image
Matulon Plus Tablet SR image
Matulon Plus Tablet SR image

Product introduction

Matulon Plus Tablet SR should be taken in the dose and duration as advised by your doctor. It can be taken with or without food, preferably at the same time each day. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

It may cause side effects like taste changes, nausea, diarrhea, vomiting, stomach pain, and loss of appetite. However, these are temporary and usually subside on their own. Please consult your doctor in case these do not resolve or persist for a longer duration.

Before taking Matulon Plus Tablet SR, inform your doctor if you have any kidney, liver, or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Matulon Plus Tablet SR

Benefits of Matulon Plus Tablet SR

Treatment of Polycystic ovarian syndrome (PCOS)
Women with Polycystic ovarian syndrome (PCOS) have hormonal imbalance that is responsible for irregular menstrual cycles (periods), excessive hair growth and acne. Matulon Plus Tablet SR is a combination medicine that helps in regulating hormonal imbalance as well as periods in females. It helps the body to utilise the hormone insulin and also regulates menstrual cycles. Take it as prescribed by the doctor. Do not skip any doses and follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Matulon Plus Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Matulon Plus
  • Taste change
  • Dizziness
  • Stomach pain
  • Nausea
  • Diarrhea
  • Loss of appetite

How to use Matulon Plus Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Matulon Plus Tablet SR may be taken with or without food.

How Matulon Plus Tablet SR works

Matulon Plus Tablet SR contains metformin and myoinositol, which treats polycystic ovarian syndrome (PCOS) in females. Metformin is an antidiabetic medicine which helps regulate hormones in PCOS by balancing insulin levels. This regularizes menstruation and ovulation cycles. Myo-inositol is a naturally occurring messenger which ensures proper binding of insulin to its receptors and regulates the signaling that follows the binding process. Like this, it improves body’s response to insulin, and improves hormone balance.

Quick tips

  • Matulon Plus Tablet SR is a combination of two medicines used for the treatment of polycystic ovarian syndrome (PCOS).
  • It helps support regular ovulation and menstrual cycles.
  • An upset stomach with nausea and diarrhea may occur initially. Take it with food to avoid an upset stomach.
  • Hypoglycemia (low blood sugar level) may occur when taken along with antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source for immediate relief.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Matulon Plus Tablet SR
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Matulon Plus Tablet SR is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Matulon Plus Tablet SR may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Matulon Plus Tablet SR alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Matulon Plus Tablet SR should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Matulon Plus Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver

Liver

UNSAFE
Matulon Plus Tablet SR is unsafe to use in patients with liver disease and should be avoided.
Matulon Plus Tablet SR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Frequently asked questions

Matulon Plus Tablet SR is a combination of two medicines: Metformin and Myo Inositol. This medicine is used in the treatment of Polycystic ovarian syndrome (PCOS). Metformin is an antidiabetic medicine which helps to regulate menstrual cycle by improving the insulin sensitivity. This helps in regularizing the menstrual cycles in women. Myo-inositol is safe and effective and acts as natural insulin sensitizer which helps to reduce androgen (male) hormones and restores ovulatory function in females.
The use of Matulon Plus Tablet SR is associated with common side effects like nausea, altered taste, diarrhea, stomach pain and loss of appetite.
Polycystic ovarian syndrome is a medical condition seen in women of childbearing age. PCOS causes irregular menstrual cycle (periods), excess levels of androgens (high level of male hormones) and polycystic ovaries (enlarged ovaries with fluid-filled sacs or follicles). Signs and symptoms include raised insulin levels leading to diabetes, irregular periods or absence of periods, weight gain, oily skin or acne, excessive hair growth (hirsutism) usually on the face, chest, back or buttocks and thinning of hair.
Yes, the use of Matulon Plus Tablet SR can cause nausea and vomiting. Taking it with milk, food or with antacids can help prevent nausea. Avoid taking fatty or fried foods along with this medicine. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to a doctor.
It is best to take Matulon Plus Tablet SR at your bed time as this will minimize the side effects caused by this medicine.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Wonne International
Address: S. Atlanta, Bldg no 1, R.C. Marg, Chembur, Mumbai - 400071

Vendor Details

Country of origin: India
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