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Reviewed By
MD Pharmacology, MBBS
Last updated
29 Nov 2023 | 06:54 PM (IST)

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Macugen 0.3mg Infusion

Prescription Required
Marketer
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Macugen 0.3mg Infusion is used in the treatment of eye condition called wet age-related macular degeneration. It reduces the abnormal growth of blood vessels in the eye. This decreases the chances of swelling as well as fluid and blood leakage that can cause vision loss.

Macugen 0.3mg Infusion is administered directly into the eyeball by an eye specialist. You should not self administer this medicine at home. The common side effects include eye pain, redness, blurred or decreased vision and eye discharge.

However, if you experience these side effects for a longer duration or any other symptoms which you think may be due to this medicine, please inform your doctor. It is not advised to drive after administration of this injection as you may feel sleepy or dizzy and your alertness may be reduced.

Uses of Macugen Infusion

Benefits of Macugen Infusion

In Wet age-related macular degeneration

Macula is the part of the retina responsible for central vision. Wet age-related macular degeneration is an eye disorder that causes blurred vision or a blind spot in your visual field due to abnormal blood vessels that leak fluid or blood into the macula. This leads to vision problems. Macugen 0.3mg Infusion helps prevent leakage of such abnormal blood vessels and therefore prevents vision loss. It is given as an injection by a doctor or nurse and should not be self-administered.

Side effects of Macugen Infusion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Macugen

  • Foreign body sensation in eyes
  • Increased intraocular pressure
  • Eye pain
  • Punctate keratitis
  • Eye floaters
  • Visual impairment
  • Cataract
  • Blurred vision
  • Eye inflammation
  • Stinging in the eyes
  • High blood pressure
  • Corneal edema
  • Eye itching
  • Conjunctival hemorrhage
  • Burning sensation in eye
  • Eye discharge

How to use Macugen Infusion

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Macugen Infusion works

Macugen 0.3mg Infusion is an anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the growth and leakage of abnormal blood vessels in the eye(s) that may cause vision loss.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Macugen 0.3mg Infusion. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Macugen 0.3mg Infusion is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Macugen 0.3mg Infusion is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Macugen 0.3mg Infusion may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Macugen 0.3mg Infusion in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Macugen 0.3mg Infusion in patients with liver disease. Please consult your doctor.

What if you forget to take Macugen Infusion?

If you miss a dose of Macugen 0.3mg Infusion, please consult your doctor.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Macugen 0.3mg Infusion is used for the treatment of an eye condition called wet age-related macular degeneration.
  • It is administered directly into the eyeball by an eye specialist.
  • It may cause temporary visual disturbances. Don't drive or do anything that requires mental focus until you know how Macugen 0.3mg Infusion affects you.
  • Inform your doctor if you experience increased eye pain and redness, blurred or decreased vision, or increased sensitivity to light.

Fact Box

Chemical Class
Oligonucleotides
Habit Forming
No
Therapeutic Class
OPHTHAL
Action Class
Vascular endothelial growth factor (VEGF) inhibitor for AMD

Patient concerns

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Macular degeneration in left eye
Dr. Richa Jain
Ophthalmology
Get Oct done. n visit
Sir, is surgery necessary in the initial stages of macular degeneration or it can be cured with medicines
Dr. Richa Jain
Ophthalmology
What kind of surgery. Macular degeneration can't be cured.Share pic of your prescription
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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Henderer JD, Rapuano CJ. Ocular Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1794.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1073.
  3. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 977.
  4. Medscape. Pegaptanib. [Accessed 04 Apr. 2019] (online) Available from:External Link
  5. Pegaptanib sodium. San Dimas, Calirfornia: Gilead Sciences, Inc.; 2004 [revised Jul. 2011]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  6. Drugs.com. Pegaptanib. [Accessed 04 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Country of origin: India

42321
Inclusive of all taxes
MRP44571.42  5% OFF
90.0 ml in 1 bottle
SOLD OUT
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