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Pegaptanib is used in the treatment of wet form of age-related macular degeneration (growth of abnormal blood vessels in eye leading to gradual loss of vision), diabetic macular edema (accumulation of fluid in eye of diabetic patients) and macular oedema due to retinal vein occlusion

How it works

Pegaptanib belongs to a class of medication called vascular endothelial growth factor (VEGF) antagonists. Pegaptanib binds extracellular VEGF thereby stopping abnormal blood vessel growth and leakage in the eye(s) which may lead to vision loss in people with wet AMD.

Common side effects

Eye disorder, Increased sensitivity to light, Bleeding around the eye, Bloodshot eye, Blurred vision, Cataract, Conjunctival inflammation, Discharge, Shortness of breath, Wheezing, Eye discomfort, Eye irritation, Eye redness, Dilatation of pupil, Eye swelling, Eyelid inflammation, Eyelid swelling, Fainting, Itching, Mouth swelling, Nausea, Stomach cramp, Tachycardia, Teary eyes, Visual impairment, Vomiting, Diarrhoea

Available Medicine

Expert advice

  • Consult your ophthalmologist immediately if the eye becomes red, sensitive to light, painful or develops a change in vision.
  • Patients should not drive or use machines immediately after receiving pegaptanib intravitreal injection which may influence the driving ability.
  • Before taking pegaptanib, inform you doctor if you are pregnant, planning a pregnancy or breast-feeding.

Frequently asked questions


Q. What is pegaptanib sodium?
Pegaptanib injection belongs to a class of medications called vascular endothelial growth factor (VEGF) antagonists. Pegaptanib is mainly used for the treatment of exudative (wet) neovascular age-related macular degeneration (AMD, a disease of the eye that affects vision).

Content on this page was last updated on 02 January, 2017, by Dr. Varun Gupta (MD Pharmacology)