Macpred 125mg Injection

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 13 Mar 2026 | 01:39 PM (IST)

Macpred 125mg Injection is a type of medicine called a steroid. It is used to treat different conditions including rheumatic disorder, asthma, severe allergic reactions and conditions that affect your eyes and skin.

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General Information

Contains

Methylprednisolone (125mg)

Marketer

Macleods Pharmaceuticals Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Macpred 125mg Injection is usually given as an injection by your doctor into a vein, joint, or muscle. The amount you are given will depend on what you are being treated for and how much you need to control your symptoms. If you are using this medication at home, learn exactly how to do it correctly from your doctor. You should always take the amount prescribed. Do not take a larger dose or use it more often. Taking a higher dose will not improve your condition faster, and your risk of side effects will increase. Keep taking it regularly even if you feel well. Do not suddenly stop this medication as your condition may become worse. It should always be stopped gradually.

The most common side effects of this medicine include nausea, headache, dizziness, sweating, and swelling in your hands or ankles (edema). If these side effects bother you or will not go away, your doctor may suggest ways of preventing or reducing them. Steroids may also lower your ability to fight infections so avoid being near people who might pass on infections such as measles, chickenpox, or flu. Do not receive a live vaccine while using this medicine. Steroids can affect growth in children.

Before using this medicine, you should tell your doctor if you have brittle bones (osteoporosis), mood disorders, high blood pressure, or liver disease. Also, tell your doctor if you have diabetes, this medicine may increase blood glucose levels which can worsen diabetes. Many other drugs may affect, or be affected by, this medicine so let your doctor know all other medicines you are using. This is done to make sure it is safe to use. You should also tell your doctor if you are pregnant, planning to become pregnant or breastfeeding. If this medicine is used for a long time you will be asked for regular monitoring of blood sugar, blood pressure, bone density as well as an eye examination.

Uses of Macpred Injection

Treatment of Allergic conditions
Treatment of Systemic lupus erythematosus (SLE)
Treatment of Skin disorders
Treatment of Eye disorders
Treatment of Rheumatic disorder

Benefits of Macpred Injection

Treatment of Allergic conditions
Macpred 125mg Injection is used to treat different inflammatory and allergic conditions including arthritis, lupus, psoriasis, ulcerative colitis which affect the skin, blood, eyes, lungs, stomach, and nervous system. It works by lowering your immune system’s response to these conditions thereby reducing symptoms such as swelling, pain, itching and other allergic-type reactions.
This medicine is given orally (by mouth). You should always take it as it has been prescribed for you. Do not stop taking it without your doctor’s advice. This can cause unpleasant withdrawal symptoms. Because this medicine weakens your immune system, you should avoid being near people who are ill or have infections.

Treatment of Systemic lupus erythematosus (SLE)
Systemic lupus erythematosus (SLE) is an autoimmune disease. In this disease, the immune system of the body mistakenly attacks healthy tissue. It can affect the skin, joints, kidneys, brain, and other organs. Macpred 125mg Injection prevents the release of substances in the body that cause inflammation. It lowers your immune system’s response and reduces symptoms such as swelling, pain, itching and other allergic-type reactions.

Treatment of Skin disorders
Macpred 125mg Injection prevents the release of substances in the body that cause inflammation. It can be used to treat different inflammatory and allergic conditions of the skin such as eczema and psoriasis. It works by lowering your immune system’s response to these conditions thereby relieving symptoms such as swelling, pain, itching and other allergic-type reactions.

Treatment of Eye disorders
Macpred 125mg Injection helps relieve symptoms of eye infections such as redness, swelling, itching and watering of eyes. This medicine works by decreasing the production of certain chemicals that cause inflammation of the eyes. This will make it easier for you to go about your daily activities. Use it as prescribed to get the most benefit. If you see no improvement even after a week, talk to your doctor.

Treatment of Rheumatic disorder
Rheumatic disorder is an autoimmune condition where your body’s immune system (which usually fights bacteria and viruses) attacks your body’s own cells. Macpred 125mg Injection stops that from happening and can relieve the symptoms of this condition such as pain, swelling, and stiffness in your joints. It can also slow down joint damage, reduce disability, and enable you to be as active for as long as possible. It can take several weeks or months to notice the effect of the medicine. You should continue taking it until your doctor says it is okay to stop using the medicine.

Side effects of Macpred Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Macpred

Nausea
Behavioral changes
Sweating
Edema (swelling)
Mood changes
Upset stomach
Thinning of skin
Increased risk of infection
Reduction in bone density

How to use Macpred Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Macpred Injection works

Macpred 125mg Injection is a steroid which works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.

All substitutes for Macpred 125mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Macpred 125mg Injection helps treat inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems that require either reduction of inflammation or suppression of the immune system.
Do not use it more often or for longer than advised by your doctor.
Macpred 125mg Injection can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.
Do not stop taking Macpred 125mg Injection suddenly without talking to your doctor first as it may worsen your symptoms.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Macpred 125mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Macpred 125mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Macpred 125mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Macpred 125mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Undesirable effects, such as dizziness, vertigo, visual disturbances and fatigue are possible after treatment with Macpred 125mg Injection. This may affect your driving ability.

Kidney

CAUTION

Macpred 125mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, talk to your doctor if you have any underlying kidney disease.

Liver

CAUTION

Macpred 125mg Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Macpred with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Methylprednisolone may reduce the efficacy of Cholera Vaccine (Inactivated).

Severe

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Do not use Methylprednisolone with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If essential, please consult your doctor. Methylprednisolone may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

It is recommended to wait at least 3 months after discontinuing a high dose of Methylprednisolone before taking Purified Vi Polysaccharide Typhoid Vaccine.

Moderate

Chloroquine (Oral Route)

Your doctor may monitor your potassium levels closely.

Moderate

Loperamide (Oral Route)

Your doctor may monitor your potassium levels closely.

Frequently asked questions

How does Macpred 125mg Injection work?

Macpred 125mg Injection works by reducing the inflammation which helps in treating many illnesses caused due to active inflammation. In addition to that, it stops the autoimmune reactions which occur when your body's immune system attacks the body itself and causes damage.

Is Macpred 125mg Injection a steroid?

Yes, Macpred 125mg Injection is a steroid medicine also known as corticosteroids which occur naturally in the body. These corticosteroids help to maintain health and wellbeing. Macpred 125mg Injection increases the levels of corticosteroids in the body by treating various illnesses involving inflammation (redness, tenderness, heat and swelling).

What is Macpred 125mg Injection used for?

Macpred 125mg Injection has anti-inflammatory and immunosuppressant properties. It is used to treat conditions like allergic conditions, anaphylaxis, asthma, rheumatoid arthritis and inflammatory skin diseases. It is also helpful in treating autoimmune diseases (these diseases happen when your body’s immune system attacks the body itself and causes damage) and certain eye disorders.

How is Macpred 125mg Injection administered?

Macpred 125mg Injection should be administered by a doctor or under the supervision of a healthcare professional and should not be self-administered. Usually, it is given into a muscle (intramuscular), joint (intra-articular), directly into a vein (direct intravenous), infusion or into the area being treated (soft tissue infiltration). The doctor will decide the dose based on the condition you are being treated for and also your body weight. Follow your doctor’s instructions carefully to get maximum benefit from Macpred 125mg Injection.

Is Macpred 125mg Injection better than Prednisone?

Clinical studies have shown that Macpred 125mg Injection is more strong and efficient than Prednisone. It stays in our body for a longer duration and is better tolerated when used in the treatment of inflammatory conditions. However, consult your doctor for the right treatment of your condition.

Does Macpred 125mg Injection cause weight gain?

Macpred 125mg Injection can cause weight gain especially when high doses taken for a long time or repeated short courses are taken. Please consult your doctor if you experience weight gain after taking Macpred 125mg Injection.

Fact Box

Chemical Class

21- hydroxysteroids

Habit Forming

Therapeutic Class

HORMONES

Action Class

Glucocorticoids

Related lab tests

Absolute Eosinophil Count

Anti Nuclear Antibody

Anti ds-DNA Antibody

Anti ds-DNA Antibody-IFA

Peripheral Smear Examination

Total IgE

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Macpred 125mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

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Macpred 125mg Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Macpred Injection

Benefits of Macpred Injection

Side effects of Macpred Injection

How to use Macpred Injection

How Macpred Injection works

All substitutes for Macpred 125mg Injection

Solu-Medrol 125mg Injection

Neo-Drol 125mg Injection

Mobilanz 125 Injection

Predvaith 125mg Injection

Predshot 125mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Chloroquine (Oral Route)

Loperamide (Oral Route)

Frequently asked questions

How does Macpred 125mg Injection work?

Is Macpred 125mg Injection a steroid?

What is Macpred 125mg Injection used for?

How is Macpred 125mg Injection administered?

Is Macpred 125mg Injection better than Prednisone?

Does Macpred 125mg Injection cause weight gain?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Absolute Eosinophil Count

Anti Nuclear Antibody

Anti ds-DNA Antibody

Anti ds-DNA Antibody-IFA

Peripheral Smear Examination

Total IgE

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests