Macorate 600 Tablet

Magnesium Valproate (600mg)

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Macorate 600 Tablet belongs to a group of medicines called anti-epileptics. It is used to treat two conditions – epilepsy and bipolar disorder. It also helps in the prevention of migraine. This way it prevents extreme mood swings and abnormal brain signals that trigger seizures (fits).

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 23 Jan 2026 | 10:15 AM (IST)

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General Information

Contains

Magnesium Valproate (600mg)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Macorate 600 Tablet can be used alone or in combination with other medicines. It may be taken with or without food. Your doctor will decide the correct dose for you. This may increase gradually until your condition is stable. This medicine may take several weeks to work but it is important to take it regularly to get the benefit. Do not stop taking it, even if you feel fine, unless your doctor advises you to. You may have more seizures, or your bipolar disorder may get worse.

The most common side effects of this medicine include skin rashes, headache, feeling or being sick, difficulty sleeping, dizziness, and feeling sleepy or drowsy. Most side effects wear off, but if they bother you or do not go away, tell your doctor. There may be ways of preventing or reducing these effects. Long-term treatment can cause weakness in your bones (osteoporosis), increasing your risk of breaking a bone.

Before taking this medicine, tell your doctor if you have kidney or liver problems, meningitis or depression, or suicidal thoughts. Also let your healthcare team know about all other medications you are using as some may affect, or be affected by, this medicine, including contraceptive pills. If you are pregnant or breastfeeding, the dose may be adjusted. You should avoid driving or riding a bicycle if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine.

Uses of Macorate Tablet

Benefits of Macorate Tablet

Epilepsy/Seizures
Macorate 600 Tablet helps prevent and control seizures (fits) by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

Bipolar disorder
Macorate 600 Tablet works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.

Side effects of Macorate Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Macorate

Headache
Dizziness
Blurred vision
Loss of appetite
Nausea
Vomiting
Sleepiness
Hair loss
Weight gain
Double vision
Diarrhea
Impaired coordination
Tremors
Weakness
Stomach pain
Increased appetite

How to use Macorate Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Macorate 600 Tablet may be taken with or without food.

How Macorate Tablet works

Macorate 600 Tablet is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Quick tips

It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Monitor your weight during treatment with this medicine as it can cause weight gain.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/laptop.
- Take your medication on time.
Macorate 600 Tablet helps in the treatment and prevention of seizures.
Take it at the same time every day to maintain consistent levels in your body.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Macorate 600 Tablet, as it may cause excessive sleepiness or drowsiness.
Monitor your weight during treatment with this medicine as it can cause weight gain.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not take Macorate 600 Tablet if you are pregnant or planning to conceive or breastfeeding.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/laptop.
- Take your medication on time.
It may increase the risk of low sodium levels in the blood. Inform your doctor if you develop difficulty concentrating, memory problems, confusion, weakness, and unsteadiness.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Macorate 600 Tablet

Pregnancy

UNSAFE

Macorate 600 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Macorate 600 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Macorate 600 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Macorate 600 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Macorate 600 Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

For how long should I take Macorate 600 Tablet to cure my epilepsy completely?

Macorate 600 Tablet does not cure your condition, it only prevents the seizures from occurring. Therefore, you will have to keep on taking it, maybe for years. Consult your doctor if face any problems while taking this medicine.

What happens if I stop taking Macorate 600 Tablet?

You should not stop taking Macorate 600 Tablet suddenly. It should be discontinued gradually. Stopping it suddenly may increase the chances of recurrence of seizures. Always consult your doctor if you feel the need to stop taking this medicine.

I have gained weight after I started using Macorate 600 Tablet. Is it because of this medicine? What should I do?

Yes, weight gain can occur with the use of Macorate 600 Tablet. To control your weight, you should have a healthy balanced diet and exercise regularly. Talk to your doctor if you have any other concerns.

Can I take birth control pills while taking Macorate 600 Tablet?

Yes, Macorate 600 Tablet does not have any effect on the working of birth control pills. However, contraceptives (birth control pills) may interfere with the working of Macorate 600 Tablet and seizures may occur. It is important that you inform your doctor that you are using birth control pills. Your doctor will keep a track on your response to the treatment and monitor the Macorate 600 Tablet levels in your blood levels.

Is it safe to take Macorate 600 Tablet for long term?

Many patients can safely take Macorate 600 Tablet for a long time. Rarely, long-term use of Macorate 600 Tablet may weaken your bones, thereby increasing their chances of breaking easily (osteoporosis and osteopenia). If you are taking Macorate 600 Tablet for a long time, get regular check ups done for bone health.

I am concerned because I have heard that Macorate 600 Tablet causes hair loss. Is it true?

Macorate 600 Tablet may cause thinning of hair, change of hair colour and even hair loss. If you are concerned talk to your doctor if it is possible to reduce the dose of Macorate 600 Tablet. Your hair may regrow after either reducing your dose or switching to a different medicine.

Fact Box

Chemical Class

Methyl- branched fatty acids

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Sodium Channel Modulators- Antiepileptic drugs (AEDs)

References

Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Vendor Details

Country of origin: India

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Why we need a prescription?

Macorate 600 Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Macorate Tablet

Benefits of Macorate Tablet

Side effects of Macorate Tablet

How to use Macorate Tablet

How Macorate Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

For how long should I take Macorate 600 Tablet to cure my epilepsy completely?

What happens if I stop taking Macorate 600 Tablet?

I have gained weight after I started using Macorate 600 Tablet. Is it because of this medicine? What should I do?

Can I take birth control pills while taking Macorate 600 Tablet?

Is it safe to take Macorate 600 Tablet for long term?

I am concerned because I have heard that Macorate 600 Tablet causes hair loss. Is it true?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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