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Losrest 12.5mg Injection

Levosulpiride (12.5mg)

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Losrest 12.5mg Injection is a medicine used in the treatment of gastrointestinal problems like functional dyspepsia, nausea, vomiting, and diabetic gastroparesis. It improves food movement and treats disorders of the stomach and intestines.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Aug 2026 | 01:02 AM (IST)

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2 ml Injection

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Gurgaon

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General Information

Contains

Levosulpiride (12.5mg)

Marketer

Arlak Biotech Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Losrest 12.5mg Injection is taken by mouth with or without food. However, it is advisable to take it at the same time each day, as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor, and if you have missed a dose, take it as soon as you remember.

Some common side effects of this medicine include headache and fatigue. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. You should immediately consult a doctor if you have absence of periods, abnormal milk secretion, changes in sexual desire, or fever after taking this medicine.

Uses of Losrest Injection

Benefits of Losrest Injection

Treatment of Functional dyspepsia
Functional dyspepsia is another term for indigestion that is not associated with a specific cause. It may cause symptoms such as an early feeling of fullness after eating, stomach pain or discomfort, nausea, and bloating. Losrest 12.5mg Injection helps treat these symptoms by increasing the rate of stomach emptying. Some simple lifestyle changes can help stop or reduce these symptoms. Think about what foods trigger your symptoms and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3 to 4 hours of going to bed.

Side effects of Losrest Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Losrest

Limited data available

How to use Losrest Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Losrest Injection works

Losrest 12.5mg Injection is an atypical antipsychotic. It works by increasing the release of acetylcholine (a chemical messenger). This increases the movement of the stomach and intestines, and prevents reflux (acid going up to the food pipe) as well as nausea or vomiting. Since it modulates the motor function of the gastrointestinal tract, it also improves delayed gastric emptying.

All substitutes for Losrest 12.5mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Let your doctor know if you have a history of seizures or unusual muscle movements, as Losrest 12.5mg Injection can sometimes affect the nervous system and trigger them.
After getting this medicine, avoid standing up too quickly to prevent sudden dizziness or feeling faint.
If you are diabetic, ask your doctor to keep an eye on your blood sugar. This medicine can sometimes affect it.
Keep track of how you feel after each dose. If your mood changes a lot or you feel too restless, share it with your doctor.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Losrest 12.5mg Injection may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Losrest 12.5mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Losrest 12.5mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Losrest 12.5mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Losrest 12.5mg Injection may cause drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Losrest 12.5mg Injection in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Losrest 12.5mg Injection in patients with liver disease.

Interaction with drugs

Taking Losrest with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Metoclopramide (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Metoclopramide (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

How does Losrest 12.5mg Injection work?

Losrest 12.5mg Injection works by blocking dopamine receptors in the gut, which helps improve digestion and reduce nausea and vomiting. It also enhances the effects of serotonin, a brain chemical that regulates mood, which helps alleviate symptoms of depression and anxiety.

Can I take Losrest 12.5mg Injection with other medicines?

Always inform your doctor about all the medicines you are taking, including over-the-counter drugs, supplements, or herbal products. Losrest 12.5mg Injection may interact with medications like antidepressants, antipsychotics, or sedatives, thereby increasing the risk of side effects.

Is Losrest 12.5mg Injection safe for everyone?

No, Losrest 12.5mg Injection may not be safe for everyone. It is not recommended for people with Parkinson’s disease or other movement disorders, severe kidney or liver problems, a history of breast cancer or high prolactin levels, and allergies to Losrest 12.5mg Injection or similar drugs. Pregnant or breastfeeding women should also consult their doctor before taking this medicine.

Can Losrest 12.5mg Injection cause weight gain?

Yes, weight gain is a possible side effect of Losrest 12.5mg Injection, which may be caused by increased appetite or hormonal changes. Your doctor may recommend a healthy diet and regular exercise to help manage your weight.

Does Losrest 12.5mg Injection make you sleepy?

Yes, drowsiness or sleepiness is a common side effect of Losrest 12.5mg Injection. Avoid driving, operating heavy machinery, or engaging in activities that require mental focus until you know how this medicine affects you.

How long does it take for Losrest 12.5mg Injection to work?

You may start noticing improvements in gastrointestinal symptoms like nausea or indigestion within a few days. For mental health conditions, it may take 2 to 4 weeks to see significant improvements. Always take the medicine as prescribed, even if you feel better.

Does Losrest 12.5mg Injection cause hormonal changes?

Yes, Losrest 12.5mg Injection can increase prolactin levels, a hormone that regulates milk production. This may lead to side effects like breast swelling, excessive milk production, or menstrual irregularities. Inform your doctor if you experience these symptoms.

What should I avoid while taking Losrest 12.5mg Injection?

Avoid activities that require alertness, such as driving or operating machinery, until you know how Losrest 12.5mg Injection affects you. Avoid taking other medications or supplements without consulting your doctor, as they may interact with Losrest 12.5mg Injection. Avoid consuming alcohol or foods that may irritate your stomach.

Is levosulpiride safe?

Levosulpiride is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Is levosulpiride an antidepressant?

No, it is used in the treatment of gastro-oesophageal reflux disease, irritable bowel syndrome, psychosis, dyspepsia

What is levosulpiride?

Levosulpiride belong to class of medication called as atypical antipsychotics. It acts by decreasing the activity of dopamine in the brain

What are its uses?

Levosulpiride is used in the treatment psychosis, depression, gastro-oesophageal reflux disease, irritable bowel syndrome and dyspepsia

Does levosulpiride cause erectile dysfunction?

No. patients should follow advice of the doctor regarding the possible side effects.

Can I take Losrest 12.5mg Injection with omeprazole?

Losrest 12.5mg Injection can be safely taken with omeprazole as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Losrest 12.5mg Injection works by increasing the gut motility and Omeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Fact Box

Chemical Class

Benzamide derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Atypical Antipsychotics

Related lab tests

Complete Blood Count

References

Lozano R, Concha MP, Montealegre A, et al. Effectiveness and safety of levosulpiride in the treatment of dysmotility-like functional dyspepsia. Ther Clin Risk Manag. 2007;3(1):149-55. [Accessed 29 Jan. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
Levosulpiride Injection [Patient Information Sheet]. Thane, Maharashtra: Torrent Pharmaceuticals Ltd. [Accessed 06 Apr. 2024] (online) Available from:
Levosulpiride [Patient Information Leaflet]. Barcelona, Spain: Ferrer Internacional, S.A.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Arlak Biotech Pvt Ltd
Address: SCO 5-6, Wadhawa Nagar, Near Hotel Sunpark, Kalka Highway, Zirakpur, Punjab 140603

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Losrest 12.5mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Home

Neuro Cns

Atypical Antipsychotics

Losrest 12.5mg Injection

Losrest 12.5mg Injection

Payment, Returns & Expiry

Cash on delivery available

7 day free return

Product expires after Dec, 2026

Price Info

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Losrest Injection

Benefits of Losrest Injection

Side effects of Losrest Injection

How to use Losrest Injection

How Losrest Injection works

All substitutes for Losrest 12.5mg Injection

Levazeo 12.5mg Injection

Ls Plus Injection

Trylevo 12.5mg Injection

Cotsul 12.5mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Metoclopramide (Oral Route)

Metoclopramide (Injection Route)

Frequently asked questions

How does Losrest 12.5mg Injection work?

Can I take Losrest 12.5mg Injection with other medicines?

Is Losrest 12.5mg Injection safe for everyone?

Can Losrest 12.5mg Injection cause weight gain?

Does Losrest 12.5mg Injection make you sleepy?

How long does it take for Losrest 12.5mg Injection to work?

Does Losrest 12.5mg Injection cause hormonal changes?

What should I avoid while taking Losrest 12.5mg Injection?

Is levosulpiride safe?

Is levosulpiride an antidepressant?

What is levosulpiride?

What are its uses?

Does levosulpiride cause erectile dysfunction?

Can I take Losrest 12.5mg Injection with omeprazole?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests