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MRP: Rs. 113 for 1 bottle(s) (100 ML solution each)
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Composition for LOSE IT

Lactulose(3.325 mg)

food interaction for LOSE IT

alcohol interaction for LOSE IT

pregnancy interaction for LOSE IT

lactation interaction for LOSE IT

It can be taken with or without food, but it is better to take it at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
It is probably safe to use during pregnancy.
Animal studies have shown no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Lactulose(3.325 mg)


Lose it 100ml solution is used to treat constipation, abnormal brain function due to liver failure (hepatic encephalopathy and coma).

How it works

Lose it 100ml solution is a synthetic sugar, belongs to class of medications called hyperosmotic laxative. Lose it 100ml solution draws water in colon, which increases pressure in the colon to then stimulate bowel movements and helps in evacuation of bowel. It also draws ammonia from the blood into the colon where it is removed from the body, thereby reducing the amount of ammonia in the blood of patients with liver disease.

Common side effects

Abdominal pain, Diarrhoea, Nausea, Stomach pain, Stomach cramp, Vomiting


1 Substitutes
Sorted By
    (200 ML solution in bottle)
    Kanad Labs
    Rs. 0.59/ML of solution
    Rs. 117.13
    save 48% more per ML of solution

Top General Physicians

  • Dr. M. K. Singh
    MBBS, MD
  • Dr. Prabhat Kumar Jha
    MBBS, MD
  • Dr. Ashutosh Shukla
    MBBS, MD, Diploma, Fellowship
  • Dr. Sushila Kataria
    MBBS, MD, Diploma
  • Dr. R. S. Rawat
    MBBS, MD

Expert advice for LOSE IT

Do not take lactulose oral solution and consult your doctor:
  • If you are allergic to lactulose or any other ingredient of solution.
  • If you have galactosemia (inability to metabolize sugar glucose properly).
  • If you have diabetes, unexplained stomachache, blockage in bowel or have risk of digestive perforation.
  • If you have intolerance to certain sugars (lactose, galactose, or fructose).
  • Stop using lactulose and call your doctor at once if you have severe or ongoing diarrhea.
  • Do not use the solution  if it becomes very dark, or if it gets thicker or thinner in texture.
  • If you are using the lactulose powder , it should be mixed with at least 4 ounces of water. You may also use fruit juice or milk to make the medication taste better.

Frequently asked questions for LOSE IT


Q. Is lactulose a stool softener, stimulant laxative?
Lactulose is stool softener, Lactulose is not a stimulant laxative it is a hyperosmotic laxative.
Q. Can I take lactulose for constipation?
 It can be taken for constipation.

Q. Is lactulose safe for diabetics?
In diabetic patients lactulose may increase the blood sugar, make you feel confused, drowsy, or thirsty. Always consult your doctor before use.
Q. Does lactulose increase blood sugar?
In diabetic patients lactulose may increase the blood sugar, make you feel confused, drowsy, or thirsty. Always consult your doctor before use.
Q. Does lactulose contain sugar?
Lactulose is a non-digestible sugar.

Q. Is lactulose over the counter?
Lactulose is available over the counter.
Q. Is lactulose fattening (makes you fat), cause wind (gas), cause weight loss and bloating?
Lactulose does not cause weight gain or weight loss. Lactulose can cause bloating and wind (gas).
Q. Is lactulose gluten free?
Lactulose is gluten free. However, please refer to package insert of the prescribed brand before use.
Q. How long can I take lactulose?
Please consult your doctor for dose and duration required.
Q. Can I take lactulose with antibiotics, omeprazole, Senokot, Fybogel, warfarin, iron tablets, senna, paracetamol, Gaviscon?
Lactulose may interact with antibiotics, omeprazole, and Gaviscon/calcium carbonate. Senokot/senna, Fybogel/ispaghula when taken with lactulose may result in diarrhea. No interactions have been observed when lactulose is taken with warfarin, iron tablets, and paracetamol. 
Q. Does lactulose contain lactose?
Lactulose contains lactose, galactose, and small amounts of fructose. Do not take lactulose if you have intolerance to these sugars.


Content on this page was last updated on 09 October, 2014, by Dr. Varun Gupta (MD Pharmacology)