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Lornasafe Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 19 Sep 2025 | 03:31 PM (IST)
Lornasafe Tablet is a pain-relieving medicine. It is used for symptomatic treatment of acute mild to moderate pain and inflammation in patients of osteoarthritis and rheumatoid arthritis.
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Lornasafe Tablet is currently sold out
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Lorsaid SD 8 Tablet
₹180₹197.29
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Lornasafe Tablet
Lornasafe Tablet
strip of 10 tablets
₹25.6
₹28.03
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Same composition
Lorsaid SD 8 Tablet
Lorsaid SD 8 Tablet
strip of 10 tablets
by Abbott
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₹180
₹15.3 per tablet

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General Information

The content is shown in English
Lornasafe Tablet image
Lornasafe Tablet image

Product introduction

Lornasafe Tablet should be taken before meals with a sufficient amount of liquid. Taking it with food is not recommended as food can reduce the effectiveness of the medicine. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.

The most common side effects of this medicine include dizziness, headache, stomach pain, upset stomach, diarrhea, nausea, vomiting, and indigestion. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.

Uses of Lornasafe Tablet

Benefits of Lornasafe Tablet

Pain relief
Lornasafe Tablet helps to relieve pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Lornasafe Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lornasafe
  • Diarrhea
  • Stomach pain
  • Upset stomach
  • Nausea
  • Vomiting
  • Indigestion
  • Dizziness
  • Headache

How to use Lornasafe Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lornasafe Tablet is to be taken empty stomach.

How Lornasafe Tablet works

Lornasafe Tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).

Quick tips

  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
  • It should be taken with food or milk to avoid getting an upset stomach.
  • It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
  • Lornasafe Tablet can raise your risk of blood clots, heart attack, or a stroke.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • It should be taken with food or milk to avoid getting an upset stomach.
  • It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
  • Lornasafe Tablet can raise your risk of blood clots, heart attack, or a stroke.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Lornasafe Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Lornasafe Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Lornasafe Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Lornasafe Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Lornasafe Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Lornasafe Tablet may not be needed in these patients. Please consult your doctor.
Liver

Liver

CAUTION
Lornasafe Tablet should be used with caution in patients with liver disease. Dose adjustment of Lornasafe Tablet may be needed. Please consult your doctor.

Interaction with drugs

Taking Lornasafe with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

Lornasafe Tablet is a nonsteroidal anti-inflammatory medicine (NSAID) used orally to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, and other musculoskeletal or joint disorders. It may also be prescribed for acute lumbar pain and postoperative pain.
Individuals should not use Lornasafe Tablet if they are allergic to Lornoxicam, aspirin, other NSAIDs, or any ingredient present in Lornasafe Tablet. This medicine should also not be used if they have peptic ulcers, history of gastrointestinal bleeding, severe liver, kidney, or heart failure, bleeding disorders, thrombocytopenia (low blood platelets), are pregnant (especially in the last 3 months), or breastfeeding, or are a child under 18 years.
Before starting Lornasafe Tablet, you should inform your doctor if you have a history of asthma, allergies, heart failure, high blood pressure, liver/kidney disease, diabetes, ulcerative colitis, Crohn's disease, lupus erythematosus, or blood coagulation disorders. Avoid alcohol, and monitor for any stomach or intestinal symptoms.
Serious side effects of Lornasafe Tablet include signs of stomach or intestinal bleeding (black or bloody stools, vomiting blood, severe abdominal pain), allergic reactions (rash, swelling, difficulty breathing), kidney or liver problems (yellowing of skin/eyes, dark urine, severe fatigue), or sudden mood changes. Consult your doctor immediately if you experience any of these symptoms.
You should take Lornasafe Tablet only as prescribed and do not use long-term unless directed, as extended use increases risk of stomach and heart complications. Relief is usually noticed within a few hours for pain, but follow your doctor’s instructions for duration.

Fact Box

Chemical Class

Amino acids and Derivatives

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Non-Selective COX 1 & 2 Inhibitors (Enolic Acid Derivatives)
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mankind Pharma Ltd
Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020

Vendor Details

Country of origin: India
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