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MD Pharmacology, MBBS
Last updated
09 Dec 2024 | 01:06 AM (IST)

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Lorbriqua 25mg Tablet

Prescription Required
Marketer
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Lorbriqua 25mg Tablet is used to treat adults with unresectable (unremovable), advanced, or recurrent forms of non-small cell lung cancer (NSCLC). It works by inhibiting an enzyme called anaplastic lymphoma kinase (ALK) and is given to patients who have an alteration in this enzyme.

Furthermore, Lorbriqua 25mg Tablet is prescribed only to those patients who no longer respond to other ALK inhibitors, such as alectinib or ceritinib. Additionally, it is also effective in treating ALK-positive NSCLC that has spread to the brain.

Take this medicine with or without food, but preferably at the same time each day. Depending on the condition and response to the treatment, the doctor may alter the dose or stop the treatment for a short time. Continue taking this medicine for as long as the doctor has prescribed, and do not stop suddenly.

Some common side effects of Lorbriqua 25mg Tablet include edema (swelling in arms, legs, hands, and feet), peripheral neuropathy (numbness and tingling feeling in joints, arms, and legs), and cognitive disorders (confusion, forgetfulness, and lack of concentration or attention). It may also cause breathlessness, fatigue, weight gain, joint pain, mood changes, and diarrhea. Consult the doctor if any of these side effects are worrisome or worsen. They may adjust the medicine dose and suggest ways to manage them.

Let the doctor know if you have any medical conditions, such as kidney or heart disease, depression, seizures, problems with the heartbeat, or breathing problems. Also, let them know if you have high blood pressure, high levels of cholesterol, or diabetes before starting the treatment with this medicine. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medications may affect the working of this tablet; therefore, tell the doctor about all the other medicines you may be taking before starting the treatment with this medicine.

There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.


Benefits of Lorbriqua Tablet

In Treatment of Non-small cell lung cancer

Lorbriqua 25mg Tablet helps shrink the tumor size and restricts the spread of cancer to other parts of the body. This medicine can effectively treat cancer that has spread to the brain because it can cross the blood-brain barrier. This barrier is a network of blood and tissue that prevents infectious bacteria and other harmful substances from entering the brain. The use of Lorbriqua 25mg Tablet helps prevent disease progression and reduce the chances of recurrence over a long period.

Side effects of Lorbriqua Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lorbriqua

  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Breathlessness
  • Mood changes
  • Weight gain
  • Fatigue
  • Edema (swelling)
  • High blood pressure
  • Diarrhea
  • Cough
  • Joint pain
  • Hypercholesterolemia (high cholesterol)
  • Increased triglyceride level in blood

How to use Lorbriqua Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lorbriqua 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Lorbriqua Tablet works

Lorbriqua 25mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lorbriqua 25mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Lorbriqua 25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CAUTION
Lorbriqua 25mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
CONSULT YOUR DOCTOR
It is not known whether Lorbriqua 25mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Lorbriqua 25mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Lorbriqua 25mg Tablet may be needed. Please consult your doctor.
However, no dose adjustment is recommended for patients with mild or moderate renal impairment.
Liver
SAFE IF PRESCRIBED
Lorbriqua 25mg Tablet is safe to use in patients with liver disease. No dose adjustment of Lorbriqua 25mg Tablet is recommended.
However, recommended dosage regimen has not been established in cases of moderate to severe hepatic impairment.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Fact Box

Chemical Class
Phenylpropanoid derivatives
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Tyrosine kinase inhibitors

Interaction with drugs

Taking Lorbriqua with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Lorlatinib may reduce blood levels of Hydroxyprogesterone. Do not consume Lorlatinib with Hydroxyprogesterone.
Lorlatinib may reduce blood levels of Conjugated Estrogens. Do not consume Lorlatinib with Conjugated Estrogens.
Fosphenytoin may reduce blood levels of Lorlatinib. Do not consume Lorlatinib with Fosphenytoin.
Lorlatinib may reduce blood levels of Hydroxyprogesterone. Do not consume Lorlatinib with Hydroxyprogesterone.
Lorlatinib may reduce blood levels of Levonorgestrel (intrauterine delivery system). Do not consume Lorlatinib with Levonorgestrel (intrauterine delivery system).

Patient concerns

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Right lung tumour cancer in upper portion In jalgaon district which oncologist is best for lung cancer.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Dr Nitin Chaudhari us best oncologist
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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Country of origin: Germany

98889
Inclusive of all taxes
MRP102000  3% OFF
30.0 tablets in 1 box
SOLD OUT
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