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24 May 2019 | 07:36 PM (IST)
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Lonex 8 mg Tablet DT

Prescription Required
SALT COMPOSITION

Overview

Uses of Lonex Tablet DT

Lonex Tablet DT side effects

Common
  • Vomiting
  • Stomach pain
  • Nausea
  • Indigestion
  • Diarrhea

How to use Lonex Tablet DT

Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Lonex 8 mg Tablet DT is to be taken with food.

How Lonex Tablet DT works

Lonex 8 mg Tablet DT is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).

Lonex Tablet DT related warnings

Alcohol
CAUTION
It is unsafe to consume alcohol with Lonex 8 mg Tablet DT. Taking Piroxicam with alcohol may increase your risk of stomach bleeding.
Pregnancy
WEIGH RISKS VS BENEFITS
Lonex 8 mg Tablet DT is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Lactation
SAFE
Lonex 8 mg Tablet DT is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Driving
Lonex 8 mg Tablet DT may make you feel dizzy, drowsy or affect your vision. Do not drive until your vision is clear.
Kidney
Lonex 8 mg Tablet DT should be used with caution in patients with severe kidney disease. Dose adjustment of Lonex 8 mg Tablet DT may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Lonex 8 mg Tablet DT should be used with caution in patients with liver disease. Dose adjustment of Lonex 8 mg Tablet DT may be needed. Please consult your doctor.

What if you miss a dose of Lonex Tablet DT?

If you miss a dose of Lonex 8 mg Tablet DT, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Expert Advice

  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Lonex 8 mg Tablet DT helps relieve pain and swelling of various joints and muscles.
  • Take it with food to avoid stomach upset.
  • Your doctor will prescribe you the lowest effective dose of this medicine for the shortest possible time necessary to relieve your symptoms.
  • It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness. 

Interaction with Drugs

Taking Lonex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Nimsun, Abinim, Nimulis
LIFE-THREATENING

Patient Concerns

Questions Related to Lonex

arrow
Dear doctor my wife is 4 month pregnant since afternoon she is suffering from head ache , can you please suggest me what should be done
Dr. Sonu Balhara Ahlawat
Infertility
Tablet Crocin pain relief can. E given
Plz dr. suggest me periods pain reliefer tablet which available easily at store.
Dr. Megha Tuli
Gynaecologist
You can take govern tablets for pain relief
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Do you have any questions related to Lonex 8 mg Tablet DT?

FAQs

Q. What is the difference between Lonex and diclofenac?

Both Lonex and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Lonex.

Q. What is the difference between Lonex and naproxen?

Both Lonex and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Lonex.

Q. What is the difference between Lonex and meloxicam?

Both Lonex and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Lonex.

Q. What is the difference between Lonex and ketoprofen?

Both Lonex and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Lonex. Ketoprofen gel also showed excellent tolerability.

Q. What is the difference between Lonex and tramadol?

Lonex is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

Q. What is the difference between Lonex and nimesulide?

Both Lonex and nimesulide are pain killers. However, Lonex is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.

Q. Can Lonex be used in the treatment of chikungunya?

Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Lonex or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Lonex.

Q. Are Lonex and aspirin same?

No. Lonex and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

Q. Can Lonex be used along with dexamethasone?

No. Lonex should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.

Q. Can Lonex be used with methocarbamol?

Yes. Methocarbamol can be used with Lonex as no serious side effects are known. Inform your doctor before starting any of the medication.

Q. Can Lonex be used along with paracetamol?

Yes. Paracetamol can be used with Lonex as no serious side effects are known. Inform your doctor before starting any of the medication.

Q. Is Lonex a NSAID?

Yes. Lonex is a non-steroidal anti-inflammatory drug (NSAID).

Q. Is Lonex a sulfa drug?

Lonex is a sulphur containing compound. Lonex can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.

Q. Is Lonex a blood thinner?

No. Lonex is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Q. Is Lonex a muscle relaxant?

No. Lonex is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Q. Is Lonex a narcotic?

No. Lonex is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

Q. Can Lonex be used in hypertension?

No. Lonex is not a medication to control hypertension. It is important to note that Lonex decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Lonex.

Q. Can Lonex be used along with Losartan?

No. Lonex should not be combined with Losartan. It is important to note that Lonex decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Lonex.

Q. Can Lonex be used with Lisinopril?

No. Lonex should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Lonex.

Q. Can Lonex be used with calcium channel blocker?

Yes. Lonex can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

Q. Can Lonex be used with Tizanidine?

Yes, Lonex can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Q. Why is beta cyclodextrin added to Lonex?

Yes. Lonex can be combined with beta-cyclodextrin. Research has shown that combining Lonex with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Q. Are there any alternatives of Lonex?

Yes. There are alternatives to Lonex. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

Q. What are the contraindications for Lonex?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.

Q. Can Lonex be used in the treatment of allergy?

No. Lonex is not a drug to treat allergy. It is a pain killer.

Q. How long does Lonex work?

Lonex is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Q. Can you get high by using Lonex?

No. Lonex is not known to cause high. It is a non-narcotic painkiller.

Q. Can Lonex be used to treat menstrual cramp?

Lonex is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.

Q. Can I use Lonex for a migraine?

Lonex is not approved for the treatment of migraine. Research studies have shown that Lonex is effective in significantly decreasing the pain associated with migraine without aura.

Q. Is Lonex effective in back pain management?

Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Lonex as the cause of back pain can be different for different person.

Q. Is Lonex affective in gout management?

Yes. Lonex can be given for the treatment of acute gout. Research studies have shown Lonex to be highly effective in the treatment of acute gout.

Q. Can you donate blood when on the medication with Lonex?

Yes. You can donate blood when on Lonex. Do inform your doctor before donating blood.

Q. Can I use Lonex if I am a diabetic?

Lonex in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Lonex so taking piroxicam can lead to increased risk of renal failure by many folds.

Q. Can I use Lonex if I have a deranged renal function?

No. Lonex should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.

Q. Can Lonex lead to skin reactions?

Yes. Lonex is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.

Q. Can I use Lonex if I am pregnant?

No. Lonex should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Q. Can I use Lonex if I have peptic ulcer disease?

No. Lonex is contraindicated in cases of active peptic ulcer disease. Lonex is known to cause gastric ulceration and bleeding.

Q. Can I use Lonex if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Q. Can Lonex lead to difficulty in conception?

Yes. Lonex can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Q. Can Lonex be used with diuretics?

No. Lonex should not be used with diuretics. Lonex reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.

Q. Can Lonex be used with lithium?

No. Lonex should not be used with lithium. Lonex leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.

Q. Can Lonex be used with warfarin?

No. Lonex should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

Q. What increases the chances of getting a gastric ulcer when I am already taking Lonex?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Lonex?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Q. What are the serious side effects of Lonex?

GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 628.
  2. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989-90.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1127-28.
  4. PubChem. Piroxicam. [Accessed 02 Apr. 2019] (online) Available from:External Link
  5. ScienceDirect. Piroxicam. [Accessed 02 Apr. 2019] (online) Available from:External Link
  6. Piroxicam. Feb. 2015. [Accessed 02 Apr. 2019] (online) Available from:External Link
  7. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Khasra No. 66/3, & 67/2, Juddi Kalan, Baddi-173205, Distt. Solan (H.P.)
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