Liofen 500 Injection is a muscle relaxer. It is used to treat muscle symptoms such as rigidity, tension, and stiffness that may occur due to various conditions such as cerebral palsy, multiple sclerosis, motor neuron disease, or injury to the head, brain or spine.
Liofen 500 Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.
The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), fatigue, drowsiness, weakness, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have ever had seizures, stomach ulcers, diabetes, problems with your heart, liver, or kidneys, etc. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Uses of Liofen Injection
Muscle relaxation
Benefits of Liofen Injection
In Muscle relaxation
Liofen 500 Injection is a muscle relaxant that is used to relieve rigidity, inflammation, and swelling in conditions that affect skeletal muscles. It works by blocking chemical messengers in the brain that are responsible for such symptoms. It effectively relieves muscle stiffness or spasm, thereby improving muscle movement.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Liofen Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Liofen
Dizziness
Convulsion
Nausea
Headache
Sedation
Hypotension (low blood pressure)
Hypotonia (decreased muscle tone)
Agitation
Constipation
Increased white blood cell count
Chills
Urinary retention
How to use Liofen Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Liofen Injection works
Liofen 500 Injection is a muscle relaxant. It works on the brain and spinal cord to relieve muscle stiffness or spasm maintaining the strength of the muscles. This relieves pain and improves movement of muscles.
Safety advice
Alcohol
UNSAFE
Liofen 500 Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Liofen 500 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Liofen 500 Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Liofen 500 Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Liofen 500 Injection should be used with caution in patients with kidney disease. Dose adjustment of Liofen 500 Injection may be needed. Please consult your doctor.
Liver
CAUTION
Liofen 500 Injection should be used with caution in patients with liver disease. Dose adjustment of Liofen 500 Injection may be needed. Please consult your doctor.
What if you forget to take Liofen Injection?
If you miss a dose of Liofen 500 Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Liofen 500 Injection provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system.
Liofen 500 Injection may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Liofen 500 Injection as it may cause excessive drowsiness.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.
Liofen 500 Injection provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system.
Take it with or after food or a glass of milk.
Liofen 500 Injection may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Liofen 500 Injection as it may cause excessive drowsiness.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.
Fact Box
Chemical Class
Gamma Amino Acids Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Centrally Acting Skeletal Muscle Relaxants
Interaction with drugs
Taking Liofen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Talk to your doctor if you notice any unusual symptoms.
Concurrent use may cause dry mouth, blurred vision, urinary retention, constipation, and confusion.
If concurrent use is essential, your doctor may monitor your respiratory and cardiovascular functions along with your overall treatment and adjust the doses as per the observations... More
Watch out for symptoms such as dry mouth, increased heart rate, urination difficulties, constipation, loss of appetite or nausea and consult your doctor if you experience them.
Co... More
Talk to your doctor if you notice any unusual symptoms.
Concurrent use may cause dry mouth, blurred vision, urinary retention, constipation, and confusion.
If concurrent use is essential, your doctor may monitor your respiratory and cardiovascular functions along with your overall treatment and adjust the doses as per the observations... More
I am taking liofen 20 for last 3 months.as i was suffering from tb meningitis i had got strokes for which my left leg is affected. does liofen 20 really increases the weight?and any substitute
I feel fear, anxiety, fast heart beat, ear tinitus Drowsy mind, No activeness, At present im taking liofen xl 20mg, and larpose 2mg, daily night
Dr. Jyoti Kapoor Madan
Psychiatry
Based in your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. To take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions.
I have been asked to take liofen XL 20. Which other tablet from other brands can replace this as , I have to take them for long duration and it's expensive.
Dr. Anshul Varshney
Physician
Welcome To 1mg. I am Anshul Varshney. Please use our 1mg app for the substitute.
Road accident. Now cured. Is physiotherapy mandatory after removal of POP?? Sir, I met with road accident exactly 63 days ago. Now POP is removed. Still can't walk without walking aid. Doctor told physiotherapy is not required. And not suggested any exercises also for muscle relaxation. Sir, please suggest me , whether I should consult another doctor or exercises not always mandatory
Dr. Akshat Goel
Orthopaedics
Physiotherapy is not mandatory Home exercises are needed for all cases
My husband is having illicit relationship bcoz of that lot of problems. I am very tensed all the time. Please suggest a medicine to calm down. Thank you
Dr. Ambrish Dharmadhikari
Psychiatry
We understand your concernWe are here to helpYou are advised to solve problemAs medicine will help you for temporary periodDiscussing with husband and finding solution will calm you downTill then you can do Jacobson Progressive Muscle Relaxation""http://www.healthline.com/health/what-is-jacobson-relaxation-technique#wholebody-technique3Follow this link to find detailed procedure
What were the side-effects while using Liofen 500 Injection?
Sleepiness
67%
No Side Effec*
33%
*No Side Effect
How do you take Liofen Injection?
Empty stomach
100%
Please rate Liofen 500 Injection on price
Expensive
100%
FAQs
Can Liofen 500 Injection make you sleepy?
Yes, Liofen 500 Injection can cause sleepiness. It can make a person dizzy due to its sedative effect. It can also affect vision and therefore you should avoid driving and using heavy machinery until and unless you know how Liofen 500 Injection affects you.
Is Liofen 500 Injection a narcotic?
No, Liofen 500 Injection is not a narcotic. It is a muscle relaxant. It does not have abuse potential. Liofen 500 Injection may cause side effects which include drowsiness, euphoria, and dysphoria. Hence, it should not be used with medicines that cause similar side effects like pain-relieving opiates.
Does Liofen 500 Injection help anxiety?
Though Liofen 500 Injection is not approved to treat anxiety disorders, it has been observed in some studies that it is effective in treating stress which occurs after a trauma.
Can I take Liofen 500 Injection if I have a liver problem?
If you have a liver problem then you need to be cautious while taking Liofen 500 Injection. This is because the medicine may increase the production of liver enzymes. Hence, regular laboratory examination of liver enzymes is required while taking this medicine as advised by your doctor.
Does Liofen 500 Injection have any effect on kidneys?
Liofen 500 Injection may cause side effects in patients with normal kidney function which include excessive day time urination (pollakiuria), burning sensation while urinating (dysuria), and loss of bladder control (urinary incontinence). Generally, a lower dose of this medicine is prescribed if a person has abnormally functioning kidneys or if a person is on dialysis.
How long does Liofen 500 Injection take to work?
Liofen 500 Injection starts working after 0.5-1 hours when the injection is given as a bolus (a large amount of medication is infused at a time). The effect of the medicine can be observed after 4 hours of administration which will last for 4-8 hours. However, if it is given as a continuous infusion then it takes about 6-8 hours to show its effect which reaches its peak within 24 to 48 hours.
What’s the most important thing that I should know about Liofen 500 Injection?
Suddenly discontinuing intrathecal (given in spinal fluid) Liofen 500 Injection injection may cause serious side effects such as high fever, severe muscle spasm, and rigidity. These side effects can progress to dangerous consequences and can even lead to death. Therefore, the medicine should be gradually reduced.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
White PF, Katzung BG. Skeletal Muscle Relaxants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 463.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 121-23.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Baclofen Pregnancy and Breastfeeding Warnings. [Accessed 02 Apr. 2019] (online) Available from: