Letroz Tablet helps treat breast cancer in post-menopausal women. It may be used alone or with other treatments, such as surgery or radiation. It can also be used in patients with advanced breast cancer to stop the tumor from spreading to other parts of the body.
Letroz Tablet can be taken with or without food. Take it in the dose and duration prescribed by the doctor to get the most benefit. The dose and frequency depend on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed.
The most common side effects of this medicine include hot flashes. If any other side effects bother you or appear serious, let your doctor know. Your doctor may suggest ways to prevent or reduce these.
Before taking this medicine, tell your doctor if you have ever had liver or kidney disease, or have a history of osteoporosis (thinning or wasting of bones). Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may perform some blood tests to check for vitamin D levels or bone density before and during treatment.
Letroz Tablet is used in the treatment of hormone-sensitive breast cancer, especially in postmenopausal women. It helps lower the risk of cancer returning and supports long-term recovery after initial treatment.
How to use Letroz Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Letroz Tablet may be taken with or without food.
How Letroz Tablet works
Letroz Tablet is an aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This decrease in estrogen can slow down or stop the growth of some breast cancers that need estrogen to grow.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Letroz Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Letroz Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding
UNSAFE
Letroz Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Letroz Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Letroz Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed. However, there is limited information on the use of this medicine in patients with end stage kidney disease. Please consult with your doctor.
Liver
CAUTION
Letroz Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
What if you forget to take Letroz Tablet?
If you miss a dose of Letroz Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Do not consume Letrozole with Allylestrenol if you have or had breast cancer. If essential, consult your doctor.
Allylestrenol may reduce the efficacy of Letrozole.
Do not consume Letrozole with Dehydroepiandrosterone (Micronized) if you have or had breast cancer. If essential, consult your doctor.
Dehydroepiandrosterone (Micronized) may redu... More
Do not consume Letrozole with Desogestrel if you have or had breast cancer. If essential, consult your doctor.
Desogestrel may reduce the efficacy of Letrozole.
I am PATIENT have pain in my breastes and feel very weight before one week of my menstrual perieds date Is it any symptoms of breast cancer ? Need your advice And also having back pain during menstrual dates please give your valubel advice
Dear PATIENT 4 Breast Cancer means that the cancer has spread to other parts of the body. The management of such cancers depends on the site where the cancer has spread and on the receptor status of the breast cancer. If you can share the details with me, I will be happy to let you know the potential management
What were the side-effects while using Letroz Tablet?
No Side Effec*
40%
Increased swe*
20%
Hot flashes
20%
Fatigue
20%
*No Side Effect, Increased sweating
How do you take Letroz Tablet?
With food
50%
With or witho*
50%
*With or without food
Please rate Letroz Tablet on price
Expensive
50%
Not Expensive
42%
Average
8%
FAQs
Why have I been prescribed Letroz Tablet?
Letroz Tablet is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy.
How does Letroz Tablet work?
Letroz Tablet is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for the production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent cancer from growing.
For how long should I take Letroz Tablet?
If the breast tumor is in the advanced stage or has spread to other parts of the body, it is recommended that you continue taking Letroz Tablet till the tumor shows progression. In cases where Letroz Tablet is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until the tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Letroz Tablet followed by 3 years of tamoxifen.
If I am taking irbesartan to control my blood pressure, can I take Letroz Tablet?
Yes, you can take irbesartan and Letroz Tablet together. However, be careful and keep a regular check on your blood pressure since Letroz Tablet may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.
Does Letroz Tablet affect vision?
Although it is very uncommon, Letroz Tablet may cause a cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.
My friend who is taking Letroz Tablet often sweats a lot. Is it because of Letroz Tablet?
This could be a sign of hot flushes which is a very common side effect of Letroz Tablet. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Letroz Tablet. However, in some people, the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.
What are the serious side effects of Letroz Tablet?
The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Letroz Tablet include stroke, angina, heart attack, blood clotting, cataract, osteoporosis, and severe skin reactions.
Does Letroz Tablet cause bone loss?
Letroz Tablet may cause thinning or wasting of your bones (osteoporosis), which is due to the decrease in estrogen levels in your body. Your doctor may decide to measure your bone density (a way of monitoring for osteoporosis) before, during and after treatment.
Can I take Letroz Tablet for induction of ovulation in anovulatory infertility?
As per the Ministry of Health and Family Welfare, Letroz Tablet is restricted for use in induction of ovulation in anovulatory infertility.
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References
Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1762.
Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 786-87.
Letrozole. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 1997 [revised Jan. 2014]. [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
National Health Service. Letrozole. [Last Reviewed: 21 Jul 2020]. [Accessed 08 Jul. 2023]. (online) Available from:
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