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Lasinone 2mg Capsule

Nitisinone (2mg)
Genuine
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Lasinone 2mg Capsule is used in the treatment of hereditary tyrosinemia, a rare disorder that occurs due to abnormal accumulation of tyrosine, a protein.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 23 Mar 2026 | 11:29 AM (IST)
₹26435 MRP ₹281256% off 
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General Information

Contains

Nitisinone (2mg)

Marketer

Laurus Labs Limited

Storage

Store below 30°C
The content is shown in English
Lasinone 2mg Capsule image
Lasinone 2mg Capsule image
Lasinone 2mg Capsule image

Product introduction

Lasinone 2mg Capsule should be taken orally, an hour before or at least 2 hours after a meal. Also, a dietary restriction of tyrosine and phenylalanine should be followed. Follow the doctor’s instructions carefully and take the dose at the same time every day to avoid missing a dose.

Some of the side effects of this medicine include elevated tyrosine levels, thrombocytopenia, leukopenia, conjunctivitis, photophobia, eye pain, epistaxis, pruritus, and alopecia. Discuss with the doctor about ways to treat or prevent any of these side effects.

Tell the doctor if you are suffering from any liver or kidney disease as dose adjustment may be required. Please consult your doctor if you can drive or consume alcohol after taking this medicine. Do not take this medicine without consulting the doctor if you are pregnant or breastfeeding.

Uses of Lasinone Capsule

  • Treatment of Hereditary Tyrosinemia Type 1

Benefits of Lasinone Capsule

Treatment of Hereditary Tyrosinemia Type 1
Hereditary tyrosinemia is a rare disorder in which there is abnormal buildup of an amino acid called tyrosine in various organs like liver, kidney, or the nervous system. The signs and symptoms may include eye pain and redness, excessively watery eyes, abnormal light sensitivity (photophobia), or thick, painful skin on the palms and soles. Lasinone 2mg Capsule stops this abnormal accumulation of tyrosine and prevents the harmful effects associated with it.

Side effects of Lasinone Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lasinone
  • Elevated tyrosine levels
  • Low blood platelets
  • Decreased white blood cell count (lymphocytes)
  • Conjunctivitis
  • Corneal opacity
  • Corneal inflammation
  • Photophobia
  • Eye pain
  • Eyelid inflammation
  • Cataract
  • Granulocytopenia
  • Nosebleeds
  • Itching
  • Exfoliative dermatitis
  • Dry skin
  • Maculopapular rash
  • Hair loss

How to use Lasinone Capsule

Take this medicine in the dose and duration as advised by your doctor. Lasinone 2mg Capsule may be taken with or without food.

How Lasinone Capsule works

Lasinone 2mg Capsule works by preventing the breaking down of an amino acid called tyrosine and by keeping other toxic substances from building up and causing harm to your liver or kidneys.

Quick tips

  • This formulation contains glycerol and may cause headaches, upset stomach, and diarrhea. Consult your doctor if these symptoms become severe.
  • Lasinone 2mg Capsule may cause vision problems, eye pain, eye redness, burning sensation and increased sensitivity of eyes to light. Seek immediate medical help in such cases.
  • You may be prescribed tests to monitor your platelet and white blood cell counts regularly while taking Lasinone 2mg Capsule. 
  • Take Lasinone 2mg Capsule on an empty stomach at least 1 hour before or 2 hours after a meal.
  • You must avoid certain foods for your treatment to be effective. Follow the diet plan created for you by your doctor.
  • If you are unable to swallow a capsule whole, open it and sprinkle the medicine into a spoonful of water. Swallow the mixture right away without chewing. Do not save it for later use.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lasinone 2mg Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Lasinone 2mg Capsule is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Lasinone 2mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Lasinone 2mg Capsule may cause temporary visual disturbances. Do not drive until your vision is clear.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Lasinone 2mg Capsule in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
Lasinone 2mg Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Lasinone with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Indinavir (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Indinavir may raise blood levels of Nitisinone.
Moderate

Adefovir (Oral Route)

If concurrent use is essential, watch out for symptoms such as weakness, headache, diarrhea, nausea, vomiting or abdominal pain and consult your doctor if you experience them. Nitisinone may raise blood levels of Adefovir.
Moderate

Atazanavir (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Atazanavir may raise blood levels of Nitisinone.
Moderate

Carbamazepine (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Moderate

Cefaclor (Oral Route)

If concurrent use is essential, watch out for symptoms such as nausea, vomiting, diarrhea, stomach pain, headache, dizziness, rash, itching, fatigue or joint pain and consult your doctor if you experience them. Nitisinone may raise blood levels of Cefaclor.

Frequently asked questions

While taking Lasinone 2mg Capsule, it is advisable to avoid tyrosine-rich foods, such as soybean, chicken, lamb, pork, fish, cheese, eggs, nuts, and beans.
It is advisable to take this medicine at least one hour before or two hours after a meal.
Yes, this medicine can cause visual disturbances, and thus avoid driving or operating any machinery after consuming this drug.
This medicine may upset the stomach and cause diarrhea due to the glycerol component of the formulation. Inform your doctor if the symptoms persist for a long or worsen.

Fact Box

Chemical Class

Benzoylcyclohexane- 1,3- diones

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

References

  1. Nitisinone [Prescribing information]. Sweden: Apotek Produktion & Laboratorier AB; 2021. [Accessed 25 Jan. 2023] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Laurus Labs Limited
Address: 2nd Floor, Serene Chambers, Road Number 5, SBI Executive Enclave, Banjara Hills, Hyderabad, Telangana 500034

Vendor Details

Country of origin: India

Lab tests offered by us

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