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MDS (Oral Pathology & Microbiology), BDS
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MD (Pharmacology), MBBS
Last updated on:
31 May 2019 | 02:50 PM (IST)
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K-Pio-Gm 1mg Tablet ER


Overview

Introduction

K-Pio-Gm 1mg Tablet ER is used in the treatment of type 2 diabetes mellitus . It is a combination medicine that can control blood sugar better than single medication. This medicine should be used along with a proper diet and exercise for best results. It should be taken with food to avoid upset stomach and it may cause hypoglycemia (low blood sugar level) as a side effect. Monitor your blood sugar level regularly while you are taking this medicine.

Uses of K-Pio-Gm Tablet ER

K-Pio-Gm Tablet ER side effects

Common
  • Hypoglycemia (low blood sugar level)
  • Nausea
  • Taste change
  • Diarrhea
  • Stomach pain
  • Headache
  • Edema (swelling)
  • Weight gain
  • Blurred vision
  • Bone fracture
  • Respiratory tract infection

How to use K-Pio-Gm Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. K-Pio-Gm 1mg Tablet ER is to be taken with food.
K-Pio-Gm 1mg Tablet ER may cause stomach upset if taken empty stomach.

How K-Pio-Gm Tablet ER works

K-Pio-Gm 1mg Tablet ER is a combination of three antidiabetic medicines: Glimepiride, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.

K-Pio-Gm Tablet ER related warnings

Alcohol
CAUTION
It is unsafe to consume alcohol with K-Pio-Gm 1mg Tablet ER. Taking pioglitazone with alcohol may affect blood glucose levels in patients with diabetes.
Pregnancy
WEIGH RISKS VS BENEFITS
K-Pio-Gm 1mg Tablet ER may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
K-Pio-Gm 1mg Tablet ER is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Monitor the breastfed baby’s blood sugar during treatment with K-Pio-Gm 1mg Tablet ER
Driving
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Kidney
CAUTION
K-Pio-Gm 1mg Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of K-Pio-Gm 1mg Tablet ER may be needed. Please consult your doctor.
Use of K-Pio-Gm 1mg Tablet ER is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
K-Pio-Gm 1mg Tablet ER should be used with caution in patients with liver disease. Dose adjustment of K-Pio-Gm 1mg Tablet ER may be needed. Please consult your doctor.
Use of K-Pio-Gm 1mg Tablet ER is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Expert Advice

  • Take it with food to lower your chance of having an upset stomach.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns

Questions Related to K-Pio-Gm

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I HAVE TYPE 2 DIABETES NOW I TAKE A MEDICINE FOR HUMINSULIN 30/70 DAY TIME 35 UNIT NIGHT 25 UNIT GLYCOMET SR 1 GM TWICE A DAY AND CARDACE 5 MG ECOSPIRIN AV 75/20 BUT I HAVE NO CONTROL OF SUGAR AND OTHER I GOT A GASTRIC PROBLEM HOW RECTIFIE THE PROBLEM NOW SUGAR LEVEL AFTER FOOD 256MG PLEASE DO THE NEED FUL. THANKING YOU
Dr. Rajesh Chhabra
Diabetes Specialist
You need to take proper precautions including dos n don't
Type 2 diabetes since 10 years. Uncontrolled.Fasting 120. PP 192. Night insulin dose 18 unit mantis + amaryllis m2 forte. Morning- voglibose GM forte 2.+Israel 100 + losakar 25.
Dr. Ashwin Porwal
Diabetes Specialist
kindly check the name of medicinesi need complete history and printed reports of following cbc urine routine and microscopy serum creatinine hba1c fbs ppbs
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User Feedback


FAQs

Q. Can I drink alcohol while taking K-Pio-Gm?

No, it is not safe to drink alcohol while using K-Pio-Gm. Drinking alcohol may lower your blood sugar levels (hypoglycemia). Also, it can increase the chances of lactic acidosis.

Q. What should I inform the doctor before taking K-Pio-Gm?

Before taking K-Pio-Gm inform your doctor if you have congestive heart failure, kidney problems, liver problems, swelling of the back of the eye. Inform the doctor if you are pregnant, breastfeeding or a premenopausal woman. Let the doctor know if you are taking any prescription and non-prescription medicines, vitamins, and herbal supplements.

Q. Can the use of K-Pio-Gm lead to Vitamin B12 deficiency?

Yes, the use of K-Pio-Gm can cause vitamin B12 deficiency as it contains metformin in it. On long-term use, it interferes with absorption of vitamin B12 in the stomach.

Q. Can the use of K-Pio-Gm cause hypoglycemia?

Yes, the use of K-Pio-Gm can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your meal, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always carry some sugary item like a candy or chocolate with you.

Q. What are the instructions for the storage and disposal of K-Pio-Gm?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Glimepiride. North Harrow, Middlesex: Accord Healthcare Limited; 2008 [revised 24 Jul. 2014]. [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Pioglitazone hydrochloride. Wooburn Green, High Wycombe: Takeda UK Ltd.; 2000 [revised 13 Sep. 2018]. [Accessed 08 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Peninsula Chambers, Peninsula Corporate Park, G.K Marg, Lower Parel (West), Mumbai - 400013, Maharashtra, INDIA.
A licensed pharmacy from your nearest location will deliver K-Pio-Gm 1mg Tablet ER. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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