Jakavi 20mg Tablet

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Manufacturer
SALT COMPOSITION
Storage
Store below 30°C

Introduction

Jakavi 20mg Tablet is used in the treatment of chronic idiopathic myelofibrosis and Polycythemia vera.

Jakavi 20mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, dizziness, low platelet count are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, kidney and lipid levels.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Jakavi Tablet

Benefits of Jakavi Tablet

In Polycythemia vera

Polycythemia vera is a type of blood cancer that causes excessive production of red blood cells. This may lead to blood clot formation and lead to other serious health issues. Jakavi 20mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

In Chronic idiopathic myelofibrosis

Chronic idiopathic myelofibrosis is a long-term problem that causes fibrous, or scar, tissue to form in the bone marrow. The scarring means the bone marrow can't work normally and produces fewer red blood cells and usually too many white blood cells. Jakavi 20mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You may experience some bothersome side effects. Discuss with your doctor if you have any doubts.

Side effects of Jakavi Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Jakavi

  • Headache
  • Dizziness
  • Low blood platelets
  • Anemia (low number of red blood cells)

How to use Jakavi Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jakavi 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Jakavi Tablet works

Jakavi 20mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety advice

Alcohol
SAFE
Consuming alcohol with Jakavi 20mg Tablet does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
Jakavi 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Jakavi 20mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Jakavi 20mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Jakavi 20mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Jakavi 20mg Tablet may be needed. Please consult your doctor.
Use of Jakavi 20mg Tablet is not advised in patients with moderate to severe kidney disease.
Liver
CAUTION
Jakavi 20mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Jakavi 20mg Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Take it with or without food, preferably at the same time each day.
  • It may cause dizziness and headaches. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Your doctor may get regular blood tests done to monitor your blood cells, liver and kidney function, and lipid levels during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
  • Do not stop taking Jakavi 20mg Tablet without talking to your doctor first.

Fact Box

Chemical Class
Pyrrolo[2,3-d]pyrimidines Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Tyrosine kinase inhibitors

Patient concerns

arrow
She suffers from polycythemia Vera for 2.5 years.pIG doctor suggest bloodlet simply.Is there any treatment to cure this disease.
Dr. Aanchal Maheshwari
Ayurveda
Ayurveda hs a hope, but case has to be personally seen , body prakruti is assesed and then treatment is given
What is reason for the psoriasis?
Dr. Souvik Sardar
Dermatology
mostly idiopathic sometimes some Medicines may be responsible for its exacerbation
arrow

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1240.
  2. Ruxolitinib. Greenville, North Carolina: DSM Pharmaceuticals, Inc.; 2011. [Accessed 24 Jan. 2019] (online) Available from:External Link
  3. Ruxolitinib. Wilmington, Delaware: Incyte Corporation; 2011 [revised Dec. 2014]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  4. Ruxolitinib. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd; 2012 [revised 22 May 2018]. [Accessed 27Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Country of origin: India

Expires on or after: March, 2022

A licensed vendor partner from your nearest location will deliver Jakavi 20mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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14 tablets in 1 strip
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