Itrafez 200mg Tablet
Product introduction
Itrafez 200mg Tablet belongs to a group of medicines called antifungals. It works by stopping the growth of fungi and is used to treat infections of the mouth, throat, vagina, and other parts of the body including fingernails and toenails. It kills fungi by destroying the fungal cell membrane.
Itrafez 200mg Tablet should be taken in the dose and duration as prescribed by your doctor. It should be swallowed whole and can be taken with food. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop the treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment. Tell your doctor if the infection does not get better or if it gets worse.
The most common side effects of this medicine include nausea, dizziness, headache, vomiting, diarrhea, abdominal pain, constipation, and dyspepsia. You could ask your doctor about ways of preventing or reducing these effects. Get emergency medical help if you have signs of an allergic reaction like severe skin rash, tingling, difficulty breathing, swelling of your face, lips, tongue, or throat.
Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking this medicine if you have a history of heart failure, a weak immune system (including HIV/AIDS), kidney problems, or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver by testing your blood.
Uses of Itrafez Tablet
Benefits of Itrafez Tablet
In Treatment of Fungal infections
Itrafez 200mg Tablet is an antifungal medicine. It is used to treat infections in different parts of the body caused by fungi. It works by killing and stopping the growth of fungi. This provides relief from various symptoms caused by the infection and speeds up the healing process. You should keep taking the medicine until you complete the dose even if you get better. This will prevent the infection from returning.
Side effects of Itrafez Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Itrafez
- Headache
- Nausea
- Abdominal pain
How to use Itrafez Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Itrafez 200mg Tablet is to be taken with food.
How Itrafez Tablet works
Itrafez 200mg Tablet is an antifungal medication. It kills fungi by destroying the fungal cell membrane. This treats your skin infection.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Itrafez 200mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Itrafez 200mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Itrafez 200mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Itrafez 200mg Tablet may cause side effects which could affect your ability to drive.
Itrafez 200mg Tablet can sometimes cause dizziness, blurred/double vision or hearing loss. This may affect your ability to drive.
Itrafez 200mg Tablet can sometimes cause dizziness, blurred/double vision or hearing loss. This may affect your ability to drive.
Kidney
CAUTION
Itrafez 200mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Itrafez 200mg Tablet may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Itrafez 200mg Tablet in patients with liver disease. Please consult your doctor.
Inform your doctor if you develop signs of jaundice like yellowing of eyes and skin, itching, and clay colored stools while taking this medicine.
Inform your doctor if you develop signs of jaundice like yellowing of eyes and skin, itching, and clay colored stools while taking this medicine.
What if you forget to take Itrafez Tablet?
If you miss a dose of Itrafez 200mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Itrafez 200mg Tablet
₹18.4/Tablet
IT Mac 200mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹15.68/tablet
15% cheaper
Quick tips
- Itrafez 200mg Tablet helps treat fungal infections of mouth, skin, vagina or any other parts of the body.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Take it with food, preferably at the same time everyday.
- Use a reliable method of contraception to prevent pregnancy while taking this medicine.
- Do not take indigestion remedies (antacids) within 2 hours of taking Itrafez 200mg Tablet.
- Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
- Inform your doctor if you develop allergic reactions, nerve pain, or hearing loss.
- Your doctor has prescribed Itrafez 200mg Tablet to cure your infection and improve symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better.
Fact Box
Chemical Class
Azoles {Triazoles}
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Fungal Ergosterol Synthesis Inhibitor
Interaction with drugs
Taking Itrafez with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Domperidone with Itraconazole.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Simvastatin with Itraconazole. If Itraconazole is essential, your doctor may temporarily stop Simvastatin. Itraconazole may raise blood levels of Simvastatin.
Concur
Do not consume Methylergometrine with Itraconazole. Itraconazole may raise blood levels of Methylergometrine.
Concurrent use may cause gangrene of fingers and toes.
Do not consume Ranolazine with Itraconazole.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Ivabradine with Itraconazole. Itraconazole may raise blood levels of Ivabradine.
Patient concerns
FAQs
What is Itrafez 200mg Tablet used for?
Itrafez 200mg Tablet is used to treat fungal infections caused by Trichophyton spp., Microsporum spp., and Epidermophyton floccosum. The infections caused could be ringworm infection, infection of the feet, or infection in the groin and buttocks. This medicine also treats persistent infection of fingernails and toenails, persistent candida (yeast) infections of vagina or candida (yeast) infections of the mouth or throat in patients with lower disease resistance. It is also used in the treatment of cryptococcal infection and infections caused by Histoplasma, aspergillus, and Blastomyces.
For how long do I need to take Itrafez 200mg Tablet?
The dose and length of treatment depends on the type and site of infection and your response to the treatment. For example, if you are taking Itrafez 200mg Tablet for athlete’s foot (fungal infection of the skin on the feet and between the toes), the dose may need to be taken for 30 days, on the other hand, if you are taking it for candidal infection of the vagina, the dose may span from 1 day to 3 days depending on the dosage advised by the doctor.
I am taking Itrafez 200mg Tablet for nail infection but there does not seem to be any improvement. Can I stop taking it?
No, you should not stop taking Itrafez 200mg Tablet without completing the entire course because doing so may not completely cure the fungal infection. It usually takes about 6-9 months for nail lesions to disappear because after the medicine eliminates the fungus, the new nail takes several months to grow. Do not worry if you do not see any improvement during the treatment.
Why has my doctor asked me to get blood tests done?
Your doctor is probably trying to monitor your liver’s functioning. Itrafez 200mg Tablet may cause serious liver damage. Therefore, if you develop loss of appetite, nausea, vomiting, dark urine, or abdominal pain while taking Itrafez 200mg Tablet, you should tell your doctor immediately.
Can I take antacid and Itrafez 200mg Tablet together?
Itrafez 200mg Tablet can be utilized by the body if there is sufficient acid in the stomach. Medicines for stomach ulcers, heartburn, or indigestion neutralize the acid produced by the stomach. Therefore, take antacids or any such medicine about 2 hours after taking Itrafez 200mg Tablet. If you are taking antacids (medicines that stop the production of stomach acid), take Itrafez 200mg Tablet capsules with a drink of cola.
What is drug resistance? Is it possible to develop resistance to Itrafez 200mg Tablet?
Sometimes it happens that the fungi get modified in your body and the medicine no longer works. This is called drug resistance. Resistance to Itrafez 200mg Tablet has been reported with some candida species (krusei, glabrata, and tropicalis). Itrafez 200mg Tablet should not be used for infection caused due to these species. Take the complete course of Itrafez 200mg Tablet to avoid drug resistance.
I have been on alprazolam for quite some time. Is it okay if I start Itrafez 200mg Tablet now?
Yes, you can take both Alprazolam and Itrafez 200mg Tablet together, but keep a watch on the side effects of alprazolam such as lightheadedness or drowsiness. If side effects appear after taking Itrafez 200mg Tablet, talk to your doctor who will modify the dose of alprazolam.
My doctor prescribed Itrafez 200mg Tablet to me but not to my friend who had a similar fungal infection because she was on dofetilide. Why is it so?
Your doctor did not prescribe Itrafez 200mg Tablet to your friend because Itrafez 200mg Tablet interferes with the working of dofetilide. This interference can cause disturbed electrical activity of the heart, which can be harmful to the patient.
What is Itrafez 200mg Tablet used for?
Itrafez 200mg Tablet is used to treat fungal infections caused by Trichophyton spp., Microsporum spp., and Epidermophyton floccosum. The infections caused could be ringworm infection, infection of feet, or infection in groin and buttocks. This medicine also treats persistent infection of fingernails and toenails, persistent candida (yeast) infections of vagina or candida (yeast) infections of the mouth or throat in patients with lower resistance to disease. It is also used in the treatment of cryptococcal infection and infections caused by histoplasma, aspergillus and blastomyces.
For how long do I need to take Itrafez 200mg Tablet?
The dose and length of treatment will depend on the type and site of infection and your response to the treatment. For example, if you are taking Itrafez 200mg Tablet for athlete’s foot (fungal infection of the skin on the feet and between the toes), the dose may need to be taken for 30 days. While, on the other hand, if you are taking it for candidal infection of vagina, the dose may take about 1 to 3 3 days depending on the dosage advised by the doctor.
What should I do if I skip a dose of Itrafez 200mg Tablet?
If you forget to take your dose, take the missed dose as soon as you remember. However, if it is time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the forgotten dose.
I am taking Itrafez 200mg Tablet for nail infection but there does not seem to be any improvement. Can I stop taking it?
No, you should not stop taking Itrafez 200mg Tablet without completing the entire course. This is because if you stop the medication then your fungal infection may not get completely cured. It usually takes about 6-9 months for the nail lesions to get cured and after that the new nail also takes several months to grow. Therefore, do not worry if you do not see any improvement during the treatment.
Why has my doctor asked me to get blood tests done?
Your doctor may have prescribed blood tests to monitor your liver’s functioning. This is because the use of Itrafez 200mg Tablet may cause serious liver damage. Therefore, if you develop loss of appetite, nausea, vomiting, dark urine or abdominal pain while taking Itrafez 200mg Tablet, immediately inform your doctor.
Can I take an antacid and Itrafez 200mg Tablet together?
Itrafez 200mg Tablet can be utilized by the body if there is sufficient acid in the stomach. Medicines for stomach ulcers, heartburn or indigestion neutralize the acid produced by the stomach. Therefore, it is advised to avoid taking antacids or any such medicine for a minimum of 2 hours after taking Itrafez 200mg Tablet. However, if you are taking antacids (medicines that stop the production of stomach acid), take Itrafez 200mg Tablet capsules with a drink of cola.
What is drug resistance? Is it possible to develop resistance to Itrafez 200mg Tablet?
Drug resistance is a condition when the fungi get modified in your body and the medicine is not able to work. There are reports which suggest resistance of some candida species (krusei, glabrata and tropicalis) with Itrafez 200mg Tablet. Itrafez 200mg Tablet should not be used for infection caused due to these species. It is advised to take the complete course of Itrafez 200mg Tablet to avoid drug resistance.
I am on alprazolam for quite some time. Is it okay if I start Itrafez 200mg Tablet now?
Yes, you can take both Alprazolam and Itrafez 200mg Tablet together, but keep a watch on the side effects of Alprazolam such as lightheadedness or drowsiness. If you experience side effects after taking Itrafez 200mg Tablet, talk to your doctor who will modify the dose of alprazolam.
My doctor prescribed Itrafez 200mg Tablet to me but not to my friend who had a similar fungal infection because she was on dofetilide. Why is it so?
Your doctor did not prescribe Itrafez 200mg Tablet to your friend because Itrafez 200mg Tablet interferes with the working of dofetilide. This interference can cause disturbed electrical activity of the heart, which can be harmful for the patient.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1576-79.
- Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 839-40.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 749-51.
- Itraconazole. Turnhout, Belgium: Sanico N.V.; 1992 [revised Apr. 2010]. [Accessed 29 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:
- New Zealand Data Sheet. Itrazole. Aukland, new Zealand: Viatris Ltd.; 2022. [Accessed 07 Jul. 2023]. (online) Available from:
- Kurn H, Wadhwa R. Itraconazole. [Updated 2023 Apr 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 07 Jul. 2023]. (online) Available from:
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Country of origin: India
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