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Itrafaze 200 mg Tablet


Overview

Introduction of Itrafaze Tablet

Itrafaze 200 mg Tablet belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat infections of the mouth, throat, vagina and other parts of the body including fingernails and toenails. It kills fungi by destroying the fungal cell membrane.

Itrafaze 200 mg Tablet should be taken in the dose and duration as prescribed by your doctor. They should be swallowed whole and taken with food. The dosage and length of treatment will depend on the condition you are being treated for. Sometimes this will be in cycles of use and non-use. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment. Tell your doctor if the infection does not get better or if it gets worse. Avoid taking antacid treatments within one hour before or two hours after you take it.

The most common side effects of this medicine include stomach pain, headache and feeling sick (nausea). You may also experience problems with menstrual periods, runny nose, cough and cold, blurred vision, hearing loss, constipation, diarrhea and indigestion. You could ask your doctor or pharmacist about ways of preventing or reducing these effects. You should stop taking it straight away if you have any signs of an allergic reaction or of congestive heart failure. Signs of this include rash, swelling of the lips, throat or face, swallowing or breathing problems, feeling dizzy or faint and nausea.

Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking it if you have ever had heart failure, a weak immune system (including HIV/AIDS), kidney problems or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver by testing your blood. The drugs may make you dizzy or have blurred vision so do not drive or operate machines until it is safe.

Uses of Itrafaze Tablet

Itrafaze Tablet side effects

Common
  • Nausea
  • Diarrhea
  • Stomach pain
  • Skin rash
  • Increased liver enzymes

How to use Itrafaze Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Itrafaze 200 mg Tablet is to be taken with food.
If you are taking oral solution, it should be taken one hour before any food or drink.

How Itrafaze Tablet works

Itrafaze 200 mg Tablet is an antifungal medication. It kills fungi by destroying the fungal cell membrane. This treats your skin infection.

Itrafaze Tablet related warnings

Alcohol
CAUTION
Caution is advised when consuming alcohol with Itrafaze 200 mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Itrafaze 200 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Lactation
CONSULT YOUR DOCTOR
Itrafaze 200 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Itrafaze 200 mg Tablet may cause side effects which could affect your ability to drive.
Itrafaze 200 mg Tablet can sometimes cause dizziness, blurred/double vision or hearing loss. This may affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Itrafaze 200 mg Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Itrafaze 200 mg Tablet in patients with liver disease. Please consult your doctor.
Inform your doctor if you develop signs of jaundice like yellowing of eyes and skin, itching, and clay colored stools while taking this medicine.

What if you miss a dose of Itrafaze Tablet?

If you miss a dose of Itrafaze 200 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Itrafaze 200 mg Tablet
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Expert Advice

  • Itrafaze 200 mg Tablet helps treat fungal infections of mouth, skin, vagina or any other parts of the body.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Take it with food, preferably at the same time everyday.
  • Use a reliable method of contraception to prevent pregnancy while taking this medicine.
  • Do not take indigestion remedies (antacids) within two hours of taking Itrafaze 200 mg Tablet.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Inform your doctor if you develop  allergic reactions, nerve pain, or hearing loss.

Interaction with Drugs

Taking Itrafaze with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): R Zep
LIFE-THREATENING
Brand(s): Zipris
LIFE-THREATENING
Brand(s): Cizonil
LIFE-THREATENING
Brand(s): Suclosz, Vizopin
LIFE-THREATENING
Brand(s): Antep
LIFE-THREATENING
Brand(s): Oladac
LIFE-THREATENING
Brand(s): Quitsun, Qutec
LIFE-THREATENING
Brand(s): Loxaris
LIFE-THREATENING
Brand(s): Stozen
LIFE-THREATENING
Brand(s): Arifril
LIFE-THREATENING

Patient Concerns

Questions Related to Itrafaze

arrow
Pregnancy gap after intake itrafaze 100mg
Dr. Suman Rao
Gynaecologist
You can plan a pregnancy if you are not taking the tab right now
fungal infections about 4-5 year old
Dr. Aanchal Maheshwari
Ayurveda
Take gandhak rasayan 1 tablet twice, Nimbadi churan half spoon thrice, Apply Jatyadi oil on the area
arrow
Do you have any questions related to Itrafaze 200 mg Tablet?

User Feedback


FAQs

Q. What is Itrafaze used for?

Itrafaze is used to treat fungal infections caused by Trichophyton spp., Microsporum spp., and Epidermophyton floccosum. The infections caused could be ringworm infection, infection in groin and buttocks and infection of feet. This medicine also treats persistent infection of finger nails and toe nails, persistent candida (yeast) infections of vagina, candida (yeast) infections of the mouth or throat in patients with lower resistance to disease, cryptococcal infection, and infections caused by histoplasma, aspergillus and blastomyces.

Q. For how long do I need to take Itrafaze?

The dose and length of treatment depends on the type and site of infection and your response to the treatment. For example, if you are taking Itrafaze for athlete’s foot (fungal infection of the skin on the feet and between the toes), the dose may need to be taken for 30 days, while for candidal infection of vagina, the dose may span from 1 day to 3 days depending on the dosage advised by the doctor.

Q. What should I do if I skip a dose of Itrafaze?

Take the missed dose as soon as you remember it. However, if it is time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the forgotten dose.

Q. I am taking Itrafaze for nail infection but there does not seem to be any improvement. Can I stop taking it?

No, you should not stop taking Itrafaze. Complete the entire course because if you do not complete the course, your infection will not be completely cured of the fungal infection. Nail lesions usually take about 6-9 months to disappear after treatment because after the medicine eliminates the fungus, the new nail takes several months to grow. Do not worry if you see any improvement during the treatment. The medicine will remain in your nails for several months and keep doing its job.

Q. Why has my doctor asked me to get blood tests done?

Your doctor is probably trying to monitor your liver’s functioning. Itrafaze may cause serious liver damage. Therefore, if you develop loss of appetite, nausea, vomiting, dark urine or abdominal pain while taking Itrafaze, you should tell your doctor immediately.

Q. Can I take antacid and Itrafaze together?

Itrafaze can be utilized by the body if there is sufficient acid in the stomach. Medicines for stomach ulcers, heartburn or indigestion neutralize the acid produced by the stomach. Therefore, take any such medicine for about 2 hours after taking Itrafaze. If you are taking antacids (medicines that stop the production of stomach acid), you should take Itrafaze capsules with a drink of cola.

Q. What is drug resistance? Is it possible to develop resistance to Itrafaze?

Sometimes it happens that the fungi gets modified in your body and the medicine no longer works. This is called drug resistance. Resistance to Itrafaze has been reported with some candida species (krusei, glabrata and tropicalis). Itrafaze should not be used for infection caused due to these species.. Take the complete course of Itrafaze to avoid drug resistance.

Q. I am on alprazolam for quite some time. Is it okay if I start Itrafaze now?

Yes, you can take both alprazolam and Itrafaze together, but keep a watch on the side effects of alprazolam. If side effects appear after taking Itrafaze, talk to your doctor who will modify the dose of alprazolam.

Q. My doctor prescribed Itrafaze to me but not to my friend who had similar fungal infection because she was on dofetilide. Why is it so?

Your doctor did not prescribe Itrafaze to your friend because Itrafaze interferes with working of dofetilide. This interference can cause disturbed electrical activity of heart, which can be detrimental for the patient.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1576-79.
  2. Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 839-40.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 749-51.
  4. Itraconazole. Camberley, Surrey: Sandoz Limited; 2009 [revised 31 Aug. 2018]. [Accessed 29 Mar. 2019] (online) Available from:External Link
  5. Itraconazole. Turnhout, Belgium: Sanico N.V.; 1992 [revised Apr. 2010]. [Accessed 29 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:External Link
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