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Istamet 50mg/500mg Tablet

Istamet 50mg/500mg Tablet

15 tablets
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Product introduction

Istamet 50mg/500mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes, such as kidney damage and blindness and may reduce your chances of having a heart attack or stroke.


Istamet 50mg/500mg Tablet may be prescribed alone or along with other diabetes medications. It works best when used along with a healthy diet and regular exercise. Your dose will depend on your condition, blood sugar levels, and other medicines you are taking. Taking it with meals helps to reduce the chances of developing an upset stomach.

To get the most benefit, you should take it regularly, at the same time each day, and you should not stop unless your doctor recommends it. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking Istamet 50mg/500mg Tablet include diarrhea, upper respiratory tract infection, and headache. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea. Hence, you need to know how to recognize and deal with it.

This medicine is not suitable for everyone. Before taking it, you should let your doctor know if you have ever had kidney, liver, or heart disease, problems with your pancreas, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medicines may affect Istamet 50mg/500mg Tablet, so tell your doctor about all the other medicines you are taking to ensure you are safe. You should try to avoid drinking alcohol as it lowers blood glucose. Your doctor will check your kidney function and blood sugar levels before and during treatment.

Benefits of Istamet Tablet

Treatment of Type 2 diabetes mellitus
Istamet 50mg/500mg Tablet is a combination of two medicines that work together in different ways to lower your blood glucose levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level, your risk of getting any of the serious complications of diabetes, such as kidney damage, eye damage, nerve problems, and loss of limbs, is also lowered. Additionally, proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly, along with appropriate diet and exercise, will help you live an everyday, healthy life. You should keep using this medicine for as long as prescribed because it protects your future health.

In patients whose blood sugar is not controlled with metformin and another medicine, this combination may be used along with medicines such as sulfonylureas, insulin, or pioglitazone to improve blood sugar control.

Side effects of Istamet Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Istamet
  • Diarrhea
  • Stomach pain
  • Flatulence
  • Constipation
  • Vomiting
  • Nausea

How to use Istamet Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Istamet 50mg/500mg Tablet should be taken with or after food.

How Istamet Tablet works

Istamet 50mg/500mg Tablet is a combination of two medicines: sitagliptin and metformin. Sitagliptin helps your pancreas produce more insulin, facilitates effective use of insulin by the body, and reduces excess sugar that your liver makes. Metformin is a biguanide that lowers glucose production in the liver, delays glucose absorption from the intestines, and increases the body's sensitivity to insulin. Together, they provide better control of blood sugar.

Quick tips

  • Take Istamet 50mg/500mg Tablet with food to lower your chance of having an upset stomach.
  • Take it in addition to regular exercise and a healthy diet to lower blood sugar levels.
  • The chances of weight gain and low blood sugar are lower than with other diabetes medicines.
  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain, as Istamet 50mg/500mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
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15 tablets
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Generic alternative available
Contains Sitagliptin (50mg) + Metformin (500mg)
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Istamet 50mg/500mg Tablet
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Sitaford M 50mg/500mg Tablet
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