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Written By
PhD (Pharmacology), PGDPRA
Reviewed By
MD (Pharmacology), MBBS
Last updated on:
17 Jul 2019 | 12:04 PM (IST)
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Isorifazin Forte 300 mg/200 mg/750 mg Tablet


Overview

Uses of Isorifazin Forte Tablet

Isorifazin Forte Tablet side effects

Common
  • Nausea
  • Vomiting
  • Fever
  • Rash
  • Dark colored urine
  • Sweating
  • Increased sputum production
  • Salivation
  • Teary eyes
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Increased liver enzymes
  • Jaundice
  • Increased uric acid level in blood
  • Gout

How to use Isorifazin Forte Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isorifazin Forte 300 mg/200 mg/750 mg Tablet is to be taken empty stomach.
Avoid Isorifazin Forte 300 mg/200 mg/750 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Isorifazin Forte Tablet works

Isorifazin Forte 300 mg/200 mg/750 mg Tablet is a combination of three medicines: Isoniazid, Pyrazinamide and Rifampicin which treat tuberculosis. Isoniazid prevents the TB bacteria from forming their own protective covering while Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by these bacteria to make essential proteins and to reproduce. Together, they kill the bacteria and eradicate the infection. Pyrazinamide, on the other hand works by slowing the growth of these bacteria.

Isorifazin Forte Tablet related warnings

Alcohol
CAUTION
Isorifazin Forte 300 mg/200 mg/750 mg Tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Pregnancy
WEIGH RISKS VS BENEFITS
Isorifazin Forte 300 mg/200 mg/750 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
Isorifazin Forte 300 mg/200 mg/750 mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Do not drive unless you are feeling well.
You may feel dizzy or faint, have problems with vision or have other side effects that could affect your ability to drive.
Kidney
CAUTION
Isorifazin Forte 300 mg/200 mg/750 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Isorifazin Forte 300 mg/200 mg/750 mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Isorifazin Forte 300 mg/200 mg/750 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Isorifazin Forte 300 mg/200 mg/750 mg Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advised before and after the start of the treatment.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Patient Concerns

Questions Related to Isorifazin Forte

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Sir,I'm a tb patient ,doctor give me medicine,but i don't know how i take this medicine ,before meal or after meal please help meThis is my medicineSolonex 300 mg R cin 600mg Pyzina 1500mg combutol 1000mg Pyridoxin 40mg
Dr. Pushkar Mani
Diabetes Specialist
That u have to ask ur and also u visit dots centre for tuberculosis tratment
I'm suffering from intestinal tuberculosis. Started medicine from March 3,16.my knee and ankle joints are paining. advice me to take oxcq 200.should I take.how it will harm me
Dr. Vipul Aggarwal
Bone & Joint Specialist
Need to be seen and examined. Difficult to say without it to what may be the cause
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Do you have any questions related to Isorifazin Forte 300 mg/200 mg/750 mg Tablet?

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 09 Apr. 2019] (online) Available from:External Link
  2. Drugs.com. Pyrazinamide. [Accessed 09 Apr. 2019] (online) Available from:External Link
  3. Drugs.com. Rifampicin. [Accessed 09 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
3001 Red Lion Road, Philadelphia, PA, 19114, USA
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