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Histakind 180mg Tablet

Fexofenadine (180mg)
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Histakind 180mg Tablet is an anti-allergy medicine used to treat chronic idiopathic urticaria, a condition that causes red, itchy skin welts lasting more than six weeks. It works by blocking histamine, a substance that causes allergy symptoms.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 11 Jun 2026 | 05:04 PM (IST)
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Histakind 180mg Tablet
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General Information

The content is shown in English
Histakind 180mg Tablet image
Histakind 180mg Tablet image

Product introduction

Take Histakind 180mg Tablet as prescribed, preferably with a meal. The dose you receive may depend on the severity of your condition and how you respond to the medication. Keep taking this medicine for as long as your doctor recommends. Do not stop taking it without consulting your doctor.


The most common side effects are headache, drowsiness, dizziness, and nausea. Most of these are temporary and usually resolve with time. Consult your doctor if any of these side effects do not resolve or persist for a longer duration.


Do not self-medicate or recommend your medicine to another person, even if you see a similarity in symptoms. Inform your doctor if you are suffering from any problems related to the kidneys, liver, or heart. Pregnant and breastfeeding mothers should not take this medicine without consulting a doctor.

Uses of Histakind Tablet

  • Treatment of Chronic Idiopathic Urticaria

Benefits of Histakind Tablet

Treatment of Chronic Idiopathic Urticaria
Histakind 180mg Tablet is used to treat chronic idiopathic urticaria, a condition that causes persistent hives, itching, and skin redness without a known cause. It works by blocking histamine, a chemical that causes allergic skin reactions. This helps reduce itching, swelling, and hives. Regular use can help prevent flare-ups and improve skin comfort over time.

Side effects of Histakind Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Histakind
  • Headache
  • Dizziness
  • Nausea
  • Drowsiness

How to use Histakind Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Histakind 180mg Tablet should be taken with or after food.

How Histakind Tablet works

Histakind 180mg Tablet belongs to a class of medicines called antihistamines. It blocks the effects of natural chemical substances (histamine) produced in the body during an allergic state and subsides (lowers) your immune system’s response to these conditions.

Quick tips

  • Avoid drinking fruit juices (such as apple or orange juice), as they may affect the absorption of this medicine and reduce its effectiveness.
  • Avoid using antacids 30 minutes before or after taking this medicine, as they can make it harder for your body to absorb the medicine.
  • Never give this medicine to someone who appears to have a similar illness. It should be taken only if prescribed by a doctor.
  • Do not drink alcohol while taking this medication, as it may increase the risk of sleepiness.
  • Stop taking Histakind 180mg Tablet at least 3 days before undergoing an allergy test, as it can affect the test results.
  • If you notice a rapid heartbeat, irregular pulse, or a sensation of palpitations, stop taking the medication and contact your doctor immediately. These symptoms may indicate a cardiovascular side effect that requires medical attention.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Histakind 180mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Histakind 180mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Histakind 180mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

SAFE
Histakind 180mg Tablet does not usually affect your ability to drive.
However, you should make sure that Histakind 180mg Tablet does not make you feel sleepy or dizzy before driving or operating machinery.
Kidney

Kidney

SAFE IF PRESCRIBED
Histakind 180mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

SAFE IF PRESCRIBED
Histakind 180mg Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Histakind with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tepotinib (Oral Route)

Do not consume Tepotinib with Fexofenadine. If concurrent use is essential, please consult your doctor. Tepotinib may raise blood levels of Fexofenadine.
Moderate

Ulipristal acetate (Oral Route)

Ensure a gap of at least 2 hours between taking Ulipristal acetate and Fexofenadine.
Moderate

Thalidomide (Oral Route)

If concurrent use is essential, watch out for symptoms of Thalidomide side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Moderate

Enzalutamide (Oral Route)

watch out for symptoms of Fexofenadine side effects such as headaches, excessive sleepiness, dry mouth, feeling sick or dizziness and consult your doctor if you experience them. They may adjust the doses as per the observations. Enzalutamide may raise blood levels of Fexofenadine.
Moderate

Magaldrate (Oral Route)

Ensure a gap of at least 2 hours between taking Fexofenadine and Magaldrate.

Frequently asked questions

Histakind 180mg Tablet is an anti-allergic medicine that contains fexofenadine (a second-generation antihistamine). It helps reduce symptoms of chronic idiopathic urticaria, such as persistent, itchy red or skin-colored raised welts (hives). It works by blocking histamine (a chemical released during allergic reactions).
It is important to inform your doctor about any existing medical conditions and medications. This includes kidney disease, as dose adjustments may sometimes be needed while taking Histakind 180mg Tablet. Also mention if you are pregnant, planning a pregnancy, or breastfeeding. Providing a complete list of prescription or non-prescription medicines to your doctor helps identify potential interactions.
If you miss a dose, take it when you remember. However, if it is nearly time for the next scheduled dose, skip the missed dose. Do not take two doses at the same time. Since Histakind 180mg Tablet is usually taken once daily, maintaining a consistent schedule helps ensure symptom control.
People who are allergic to Histakind 180mg Tablet should not take it. In individuals with kidney impairment, reduced clearance of the drug can occur, and dose adjustment may be considered depending on the severity of the condition.
Yes, Histakind 180mg Tablet may interact with other medicines such as antacids, erythromycin, and ketoconazole. It is always better to consult your doctor and provide a list of all prescription and non-prescription medicines before taking Histakind 180mg Tablet. It is generally recommended to avoid fruit juices (such as grapefruit, orange, or apple juice) around the time of taking the dose, as these may reduce absorption.
Take Histakind 180mg Tablet exactly as directed to help manage your allergy symptoms. This medicine relieves the signs of an allergic reaction but does not treat the underlying cause; therefore, you can stop it when your symptoms have improved. If your symptoms recur after stopping the medicine or persist despite treatment, contact your doctor for further evaluation.
No. It is not an antibiotic; it is an antihistamine. Antibiotics treat bacterial infections, whereas antihistamines like Histakind 180mg Tablet relieve allergy symptoms by blocking the effects of histamine in the body.
Histakind 180mg Tablet is generally well tolerated. Common side effects may include headache, back pain, dizziness, and stomach discomfort. These are usually mild and temporary. Heart palpitations are uncommon but have been reported rarely. If unusual symptoms such as severe dizziness or irregular heartbeat occur, seek medical help immediately.
Histakind 180mg Tablet is classified as a non-sedating (non-drowsy) antihistamine because it has very limited ability to cross into the brain. It causes less sedation and may cause less drowsiness than cetirizine in some individuals. However, individual responses vary, and mild drowsiness can still occur in some people.
Histakind 180mg Tablet is usually taken once daily. It can be taken at any time of day, but taking it at the same time each day helps maintain consistent symptom control. Some people prefer taking it in the morning for daytime allergy symptoms.

Fact Box

Chemical Class

Diphenylmethanes

Habit Forming

No

Therapeutic Class

RESPIRATORY

Action Class

Second-Generation H1 Antihistamines

References

  1. RA Skidgel. Histamine, Bradykinin, and Their Antagonists. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 13th ed. New York, New York: McGraw-Hill Medical; 2018. p. 718.
  2. Golisano Children's Hospital. Treatment for a Child's Allergy to Pollen or Animals. [Accessed 22 Jan. 2021] (online) Available from:
  3. Fexofenadine Hydrochloride [Prescribing Information]. East Windsor, NJ: Aurohealth LLC; 2023. [Accessed 22 Jan. 2021] (online) Available from:
  4. Children's Allergy: Fexofenadine [Drug Facts]. Montgomery, AL: H2-Pharma, LLC; 2025.
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User feedback

Once A Day
96%
Thrice A Day
4%
Allergic conditions
100%
Excellent
75%
Average
25%
No Side Effect
100%
With or without food
50%
With food
50%
Expensive
83%
Average
17%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mankind Pharma Ltd
Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020

Vendor Details

Country of origin: India
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