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Histafree Suspension

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 03 Dec 2025 | 12:44 PM (IST)
Histafree Suspension is usually given to children to treat a wide range of symptoms caused due to allergic conditions such as hay fever, urticaria (hives), conjunctivitis (red, itchy eye), and common cold. These symptoms include watery eyes, runny nose, sneezing, and itching among others.
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General Information

The content is shown in English
Histafree Suspension image
Histafree Suspension image

Your child’s medicine at a glance

Give Histafree Suspension to your child by mouth with or without food in the dose and way prescribed by the doctor. It may be prescribed alone or in combination with other medicines. The allergic symptoms may subside after your child has taken the initial few doses of Histafree Suspension. In case of serious allergic conditions, your child may have to continue taking the medicine for a week or two. If your child vomits within 30 minutes of taking this medicine, let the child calm down and give the same dose again. However, do not repeat the dose if it is already time for the next dose.

The intake of the medicine may cause some minor and temporary side effects like nausea, vomiting, dizziness, sleepiness, and headache. These side effects should ideally diminish on their own. But, in case they persist or start bothering your child, it would be best to consult your child’s doctor without any delay.

Inform your child’s doctor if your child is on any medical regime or is allergic to any medicine, product, or food. Make sure the doctor knows if your child has or had any heart, liver, kidney problems or was born prematurely. Any history regarding bowel obstruction, malnutrition, weight-related issues, and thyroid problems should also be well indicated to the doctor to avoid any complications in the treatment. Knowing the entire medical history will help your child’s doctor make dose alterations and plan your child’s overall treatment better.

Uses of Histafree Suspension in children

Benefits of Histafree Suspension for your child

Treatment of Sneezing and runny nose due to allergies
Histafree Suspension provides relief from symptoms such as sneezing, itching, watery eyes, and runny nose. This will make it easier for you to go about your daily activities. It rarely has any serious side effects and you may only need to take it on days you have symptoms. If you are taking it to prevent getting symptoms you should use it regularly to get the most benefit.

Side effects of Histafree Suspension in children

Histafree Suspension does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Histafree
  • Dizziness
  • Headache
  • Drowsiness
  • Nausea

How can I give Histafree Suspension to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Histafree Suspension may be taken with or without food.

How Histafree Suspension works

Histafree Suspension belongs to a class of medicines called antihistamines It blocks the natural chemical substance (histamine) produced in the body during an allergic state and subsides (lowers) your child’s immune system’s response to these conditions.

All substitutes for Histafree Suspension

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Try giving the medicines at the same time each day, to help you remember.
  • Your child may feel sleepy or dizzy after each dose of Histafree Suspension. If this happens, make your child sit or lie down and ask them to be careful while performing tasks that require mental focus.
  • Avoid giving Histafree Suspension with fatty meals and fruit juice as both can reduce the absorption of the medicine.
  • Histafree Suspension should be avoided in children who are less than 12 years of age as there is a risk of respiratory distress.
  • Practice self-care tips:
    1. Abstain your child from coming in contact with allergens.
    2. Maintain a neat and clean ambiance around your child.
    3. Encourage your child to wear a face mask and avoid dusty places.
    4. Use of air conditioners instead of opening windows during the pollen season.
  • Histafree Suspension may cause less sleepiness as a side effect compared to other similar medicines.
  • Avoid drinking fruit juices (such as apple or orange) as this may affect the absorption of this medicine and cause more side effects.
  • It may cause nausea. Stick to simple meals, and do not eat rich or spicy food.
  • Avoid using antacids 30 minutes before or after taking this medicine. It can make it harder for your body to absorb this medicine.
  • Never give the medicine to someone who seems to be suffering from a similar illness. This medicine should be taken only if prescribed by a doctor.
  • Your doctor has prescribed Histafree Suspension to help relieve allergy symptoms such as itching, swelling and rashes.
  • As compared to other similar medications, it is much less likely to make you feel sleepy.
  • Be cautious while driving or doing anything that requires concentration as it can cause dizziness and sleepiness.
  • Do not drink alcohol while taking this medication as it may cause increased sleepiness.
  • Stop taking Histafree Suspension at least 3 days before taking an allergy test as it can affect the test results.

Safety advice

Kidney

Kidney

CAUTION
Histafree Suspension should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

SAFE IF PRESCRIBED
Histafree Suspension is safe to use in patients with liver disease. No dose adjustment is recommended.
However, consult your child's doctor before giving Histafree Suspension to your child in case of severe liver disease.

Interaction with drugs

Taking Histafree with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tepotinib (Oral Route)

Do not consume Tepotinib with Fexofenadine. If concurrent use is essential, please consult your doctor. Tepotinib may raise blood levels of Fexofenadine.
Moderate

Leflunomide (Oral Route)

Watch out for symptoms of Fexofenadine side effects such as headaches, excessive sleepiness, dry mouth, feeling sick or dizziness and consult your doctor if you experience them. They may adjust the doses as per the observations. Leflunomide may raise blood levels of Fexofenadine.
Moderate

Ulipristal acetate (Oral Route)

Ensure a gap of at least 2 hours between taking Ulipristal acetate and Fexofenadine.
Moderate

Thalidomide (Oral Route)

If concurrent use is essential, watch out for symptoms of Thalidomide side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Moderate

Dronedarone (Oral Route)

Watch out for symptoms of Fexofenadine side effects such as headaches, excessive sleepiness, dry mouth, feeling sick or dizziness and consult your doctor if you experience them. They may adjust the doses as per the observations. Dronedarone may raise blood levels of Fexofenadine.

Frequently asked questions

Histafree Suspension is used for treating seasonal allergic conditions such as hay fever. It helps to relieve allergies of the nose (allergic rhinitis), sneezing, runny nose, itching in the eyes, excessively watery eyes, etc.
Histafree Suspension should not be given to patients with known allergy to any other ingredients of this medicine. Signs of an allergic reaction may include an itchy skin rash, shortness of breath, and swelling of the face or tongue.
Histafree Suspension can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Histafree Suspension. Also, check with your child’s doctor before giving any medicine to your child.
Avoid giving Histafree Suspension with fatty meals and fruit juices as both can reduce the absorption of the medicine from the gut. If you need to give it to your child, ensure a gap of at least 4 hours to decrease any possible medicine-food interaction.
Histafree Suspension should be given strictly as prescribed by your child’s doctor. The dose of the medicine is calculated according to your child’s body weight and age. Do not increase or decrease the dose on your own as it may cause unwanted effects and can worsen your child’s condition.
No, refrain from giving Histafree Suspension to your child to induce sleep. Sleeplessness could be due to some other problem. Unnecessary use of Histafree Suspension may lead to side effects. It is best to consult your doctor if your child cannot sleep or if you have any queries regarding the use of this medicine.
Keep Histafree Suspension at room temperature, in a dry place, away from direct heat and light. Always keep all medicines out of the reach and sight of children to avoid any accidental intake.
Histafree Suspension is used for treating seasonal allergic conditions such as hay fever. It helps to relieve allergies of the nose (allergic rhinitis), sneezing, runny nose, itching in the eyes, excessively watery eyes, etc.
Before starting treatment with Histafree Suspension, tell your doctor if you have any other health problems, like kidneys, heart or liver-related issues. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Additionally, let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Also, inform your doctor if you are planning a baby, are pregnant, or breastfeeding.
If you forget a dose of Histafree Suspension, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Histafree Suspension should not be given to patients with known allergy to any other ingredients of this medicine. Signs of an allergic reaction may include an itchy skin rash, shortness of breath, and swelling of the face or tongue.
No. You should not stop taking Histafree Suspension even if you feel better unless your doctor tells you to stop taking it. This is because, stopping the medicine suddenly, without completing your full course of treatment may cause the returning of your symptoms and it can even worsen your condition. Consult your doctor if you are not sure.
No. Histafree Suspension is not an antibiotic. It is an anti-allergy medicine and helps to treat allergic conditions such as sneezing, stuffy or runny nose, hives, etc. On the other hand, antibiotics are used to treat infections caused by bacteria.
Yes, Histafree Suspension can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, do not drive or use any machines. It is better to rest for some time and resume once you feel better.

Fact Box

Chemical Class

Diphenylmethanes

Habit Forming

No

Therapeutic Class

RESPIRATORY

Action Class

Second-Generation H1 Antihistamines

References

  1. RA Skidgel. Histamine, Bradykinin, and Their Antagonists. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 13th ed. New York, New York: McGraw-Hill Medical; 2018. p. 718.
  2. Golisano Children's Hospital. Treatment for a Child's Allergy to Pollen or Animals. [Accessed 22 Jan. 2021] (online) Available from:
  3. National Health Services. Fexofenadine. [Last Reviewed: 14 Oct. 2021]. [Accessed 26 June 2023] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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Country of origin: India
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