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Glucoryl-M1 Forte Tablet PR


Overview

Introduction

Glucoryl-M1 Forte Tablet PR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Glucoryl-M1 Forte Tablet PR should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of Glucoryl-M1 Forte Tablet PR is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache and upper respiratory tract infection. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Glucoryl-M Tablet PR

Side effects of Glucoryl-M Tablet PR

Common
  • Hypoglycemia (low blood sugar level)
  • Taste change
  • Nausea
  • Diarrhea
  • Stomach pain
  • Headache
  • Upper respiratory tract infection

How to use Glucoryl-M Tablet PR

Use it as advised by your doctor or check the label for directions before use. Glucoryl-M1 Forte Tablet PR is to be taken with food.

How Glucoryl-M Tablet PR works

Glucoryl-M1 Forte Tablet PR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Glucoryl-M1 Forte Tablet PR.
Pregnancy
CONSULT YOUR DOCTOR
Glucoryl-M1 Forte Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Glucoryl-M1 Forte Tablet PR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Glucoryl-M1 Forte Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Glucoryl-M1 Forte Tablet PR may be needed. Please consult your doctor.
Use of Glucoryl-M1 Forte Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Glucoryl-M1 Forte Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Glucoryl-M1 Forte Tablet PR may be needed. Please consult your doctor.
Glucoryl-M1 Forte Tablet PR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Quick Tips

  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glucoryl-M1 Forte Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns

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Diabetes mellitus type 2 ,thirst
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
my diabetes 1s 150 -160 fasting I m taking glucoryl mv 2 one in morning one in night one galvus met in lunch is it write medicine
Dr. Nikhil Pursnani
Diabetology
whats your PP sugar
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User Feedback


FAQs

Q. What are the recommended storage conditions for Glucoryl-M?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can the use of Glucoryl-M lead to lactic acidosis?

Yes, the use of Glucoryl-M can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is considered to be harmful for patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Glucoryl-M and consult your doctor immediately.

Q. What is Glucoryl-M?

Glucoryl-M is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.

Q. What are the possible side effects of Glucoryl-M?

The use of Glucoryl-M is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.

Q. Can the use of Glucoryl-M lead to Vitamin B12 deficiency?

Yes, the use of Glucoryl-M can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can experience tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Q. Can the use of Glucoryl-M cause hypoglycemia?

Yes, the use of Glucoryl-M can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.

Q. Is it safe to take alcohol while I am also taking Glucoryl-M?

No, it is not safe to take Glucoryl-M along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Glimepiride + Metformin. Karachi, Pakistan: Sanofi-Aventis Pakistan Ltd. [Accessed 23 Jan. 2019] (online) Available from:External Link
  2. Metformin Hydrochloride Prolonged Release & Glimepiride Tablets I.P. Ankleshwar: Sanofi India Limited; 2018. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 08 Apr. 2019] (online) Available from:External Link
  4. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
A licensed pharmacy from your nearest location will deliver Glucoryl-M1 Forte Tablet PR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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