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Gluconorm G2 Tablet PR

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 02 Mar 2026 | 12:39 PM (IST)
Gluconorm G2 Tablet PR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
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General Information

The content is shown in English
Gluconorm G2 Tablet PR image
Gluconorm G2 Tablet PR image
Gluconorm G2 Tablet PR image
Gluconorm G2 Tablet PR image
Gluconorm G2 Tablet PR image
Gluconorm G2 Tablet PR image
Gluconorm G2 Tablet PR image

Product introduction

Gluconorm G2 Tablet PR should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you, and this may change from time to time according to how it is working, according to your blood sugar levels.


Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.


The most common side effect of Gluconorm G2 Tablet PR is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking, and know how to deal with them. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose, such as sugary food or fruit juice, with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache, and upper respiratory tract infection. Some people may find that they put on weight with this medicine.


You should not take it if you have type 1 diabetes mellitus, diabetic ketoacidosis (high levels of acid in your blood), or severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly, and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of GlUcOnorm-G Tablet PR

Benefits of GlUcOnorm-G Tablet PR

Treatment of Type 2 diabetes mellitus
Gluconorm G2 Tablet PR is a combination medicine that increases the amount of insulin your body produces (in the pancreas). The insulin then works to lower your blood glucose level. It is usually taken once a day. You should keep taking it for as long as it is prescribed.
Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of GlUcOnorm-G Tablet PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of GlUcOnorm-G
  • Headache
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Diarrhea

How to use GlUcOnorm-G Tablet PR

Use it as advised by your doctor or check the label for directions before use. Gluconorm G2 Tablet PR should be taken with or after food.

How GlUcOnorm-G Tablet PR works

Gluconorm G2 Tablet PR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea that works by increasing the amount of insulin released by the pancreas to lower the blood glucose. Metformin is a biguanide that works by lowering glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin.

Quick tips

  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Gluconorm G2 Tablet PR.
  • Take it with food to lower your chance of having an upset stomach.
  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Gluconorm G2 Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Gluconorm G2 Tablet PR
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Gluconorm G2 Tablet PR is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Gluconorm G2 Tablet PR may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CAUTION
Gluconorm G2 Tablet PR may affect your driving ability if your blood sugar becomes too low or too high. Monitor your blood glucose and avoid driving if affected.
Kidney

Kidney

UNSAFE
Gluconorm G2 Tablet PR is unsafe to use in patients with kidney disease and should be avoided.
Use of Gluconorm G2 Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Liver

Liver

UNSAFE
Gluconorm G2 Tablet PR is unsafe to use in patients with liver disease and should be avoided.
Gluconorm G2 Tablet PR is generally started with a low dose in patients with mild to moderate liver disease, and its use is not recommended in patients with severe liver disease.

Frequently asked questions

Gluconorm G2 Tablet PR is a combination of two medicines: glimepiride and metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with a proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.
Yes, the use of Gluconorm G2 Tablet PR can lead to lactic acidosis. It is a medical emergency that is caused by increased levels of lactic acid in the blood. It is also known as MALA (metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin, and therefore, it is considered to be harmful for patients with underlying kidney disease, older patients, or those who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, a feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain, or a slow heart rate. If you have these symptoms, stop taking Gluconorm G2 Tablet PR and consult your doctor immediately.
The use of Gluconorm G2 Tablet PR is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headache. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.
Yes, the use of Gluconorm G2 Tablet PR can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can experience tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.
Yes, the use of Gluconorm G2 Tablet PR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise, or take other antidiabetic medicines along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar, like glucose tablets, honey, or fruit juice, with you.
No, it is not safe to take Gluconorm G2 Tablet PR along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.

Fact Box

Habit Forming

No

Therapeutic Class

ANTI DIABETIC
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
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Fully sanitized facilities
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User feedback

Once A Day
67%
Twice A Day
33%
Type 2 diabetes mellitus
97%
Others
3%
Average
48%
Excellent
39%
Poor
13%
No Side Effect
55%
Hypoglycemia (low blood glucose level)
10%
Dizziness
7%
Abdominal pain
7%
Diarrhea
7%
Empty stomach
43%
With food
39%
With or without food
17%
Expensive
70%
Average
23%
Not Expensive
7%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Gluconorm G2 Tablet PR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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