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MDS (Oral Pathology & Microbiology), BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated on:
20 Aug 2019 | 04:44 PM (IST)
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Glimetop M 1 Tablet


Overview

Introduction

Glimetop M 1 Tablet is a medicine used in the treatment of type 2 diabetes. It is a combination of two medicines that effectively control blood sugar levels, when a single medication is not effective. It should be used along with a proper diet and regular exercise for best results. It should be taken with food to avoid the side effects like nausea and upset stomach.

Uses of Glimetop M 1 Tablet

Glimetop M 1 Tablet side effects

Common
  • Hypoglycemia (low blood sugar level)
  • Taste change
  • Nausea
  • Diarrhea
  • Stomach pain
  • Headache
  • Upper respiratory tract infection

How to use Glimetop M 1 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glimetop M 1 Tablet is to be taken with food.
Glimetop M 1 Tablet may cause stomach upset if taken empty stomach.

How Glimetop M 1 Tablet works

Glimetop M 1 Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Glimetop M 1 Tablet related warnings

Alcohol
CAUTION
It is unsafe to consume alcohol with Glimetop M 1 Tablet. Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Pregnancy
WEIGH RISKS VS BENEFITS
Glimetop M 1 Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
Glimetop M 1 Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Kidney
CAUTION
Glimetop M 1 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Glimetop M 1 Tablet may be needed. Please consult your doctor.
Use of Glimetop M 1 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Glimetop M 1 Tablet should be used with caution in patients with liver disease. Dose adjustment of Glimetop M 1 Tablet may be needed. Please consult your doctor.
Glimetop M 1 Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Expert Advice

  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glimetop M 1 Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns

Questions Related to Glimetop M 1

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Can you interpret and let me know c peptide result if that's normal. I am type 1 diabetic and I doubt this test
Dr. Ila Jain Khandelwal
Pathologist
Dear PATIENT you for sharing your reports with me. C Peptide levels are generally high in type 2 diabetes or insulin resistance while levels are generally low in type 1 diabetes. The values can also vary depending upon anti diabetic or insulin medicine if you are taking. Please consult a diabetologist for the exact interpretation.
I have type 2 diabetes. Need to know economic alternative for Jalra 50mg. Already following germe forte 2mg. Also need alternative for ivepred.
Dr. Sanjay Bhatt
Diabetes Specialist
Almost all alternatives of good company are of same priceYou need to change saltDiabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).
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FAQs

Q. What are the recommended storage conditions for Glimetop M 1?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can the use of Glimetop M 1 lead to lactic acidosis?

Yes, the use of Glimetop M 1 can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is considered to be harmful for patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Glimetop M 1 and consult your doctor immediately.

Q. What is Glimetop M 1?

Glimetop M 1 is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.

Q. What are the possible side effects of Glimetop M 1?

The use of Glimetop M 1 is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.

Q. Can the use of Glimetop M 1 lead to Vitamin B12 deficiency?

Yes, the use of Glimetop M 1 can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can experience tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Q. Can the use of Glimetop M 1 cause hypoglycemia?

Yes, the use of Glimetop M 1 can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.

Q. Is it safe to take alcohol while I am also taking Glimetop M 1?

No, it is not safe to take Glimetop M 1 along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Glimepiride + Metformin. Karachi, Pakistan: Sanofi-Aventis Pakistan Ltd. [Accessed 23 Jan. 2019] (online) Available from:External Link
  2. Metformin Hydrochloride Prolonged Release & Glimepiride Tablets I.P. Ankleshwar: Sanofi India Limited; 2018. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 08 Apr. 2019] (online) Available from:External Link
  4. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA
A licensed pharmacy from your nearest location will deliver Glimetop M 1 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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₹46.28
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