Glim 80mg/500mg Tablet


Overview

Uses of Glim Tablet

Glim 80mg/500mg Tablet is used in the treatment of type 2 diabetes.

Glim Tablet side effects

Common
  • Hypoglycemia (low blood sugar level)
  • Taste change
  • Nausea
  • Diarrhea
  • Stomach pain
  • Headache
  • Upper respiratory tract infection

How to use Glim Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glim 80mg/500mg Tablet is to be taken with food.
This medicine may cause stomach upset if taken empty stomach.

How Glim Tablet works

Glim 80mg/500mg Tablet is a combination of two antidiabetic medicines: Gliclazide and Metformin. Gliclazide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Glim Tablet related warnings

Alcohol
CAUTION
Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Pregnancy
WEIGH RISKS VS BENEFITS
Glim 80mg/500mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
Glim 80mg/500mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Kidney
CAUTION
Glim 80mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Glim 80mg/500mg Tablet may be needed. Please consult your doctor.
Use of Glim 80mg/500mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Glim 80mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Glim 80mg/500mg Tablet may be needed. Please consult your doctor.
Glim 80mg/500mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Glim 80mg/500mg Tablet
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Expert Advice

  • You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Glim 80mg/500mg Tablet.
  • Take it with food to lower your chance of having an upset stomach.
  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glim 80mg/500mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns

Questions Related to Glim

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Suffering from diabetes. Suger levels fasting 123 post lunch 177Medication before breakfast: K-Glim-M fort 2mg & Zita plus. Before dinner: K-Glim-M. Please suggest
Dr. Sanjay Bhatt
Diabetes Specialist
Continue with regular basis exercises and walk and maintain your calories intake as per your BMI
Sugar after treatment FP 253. PIOZ 15, K GLIM M 2 FORT AMARYL 1 ALL MEDICINE 1 BD. AND JANUVIA 100 OD. TELL ME TREATMENT PLEASE
Dr. Pushkar Mani
Diabetes Specialist
It's not that simple as h thinkDo USG full abdomen , URINE RE/CS, Serum SODIUM , POTASSIUM , CBC, ESR,THYROID PROFILE, LFT , SERUM CREATININE , BUN , VITAMIN D & B ESTIMATION, Hba1c , BLOOD SUGAR PP & fasting , LIPID PROFILE
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Do you have any questions related to Glim 80mg/500mg Tablet?

FAQs

Q. What is Glim?

Glim is a combination of two medicines: Gliclazide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Gliclazide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.

Q. What are the possible side effects of Glim?

The use of Glim is associated with common side effects. These side effects may include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Q. Can the use of Glim cause hypoglycemia?

Yes, the use of Glim can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.

Q. Can the use of Glim cause lactic acidosis?

Yes, the use of Glim can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin. It is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Glim and immediately consult your doctor.

Q. Can the use of Glim lead to Vitamin B12 deficiency?

Yes, the use of Glim can cause vitamin B12 deficiency on long-term use. The deficiency occurs as the medicine interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can have tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Q. Are there any specific conditions in which Glim should not to be taken?

The use of Glim should be avoided in patients with known allergy to any of the component or excipients of this medicine. It is also avoided in patients with moderate to severe kidney disease or with underlying metabolic acidosis including diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Glim?

No, it is not safe to take alcohol along with Glim. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 18th Jul 2018.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
Strides Shasun Limited, (Formerly Strides Arcolab Limited), Strides House, Bilekahalli, Bannerghatta Road, Bangalore – 560076, India
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MRP
45
10 tablets in 1 strip
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