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Last updated on:
28 Nov 2018 | 11:55 AM (IST)
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Glibamet 5mg/850mg Tablet


Overview

Uses of Glibamet Tablet

Glibamet 5mg/850mg Tablet is used in the treatment of type 2 diabetes.

Glibamet Tablet side effects

Common
  • Hypoglycemia (low blood sugar level)
  • Taste change
  • Nausea
  • Diarrhea
  • Stomach pain
  • Headache
  • Upper respiratory tract infection

How to use Glibamet Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glibamet 5mg/850mg Tablet is to be taken with food.
This medicine may cause stomach upset if taken empty stomach.

How Glibamet Tablet works

Glibamet 5mg/850mg Tablet is a combination of two antidiabetic medicines: Glibenclamide and Metformin. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Glibamet Tablet related warnings

Alcohol
CAUTION
Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Pregnancy
PROBABLY SAFE
Glibamet 5mg/850mg Tablet is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Lactation
Glibamet 5mg/850mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Kidney
UNSAFE
Glibamet 5mg/850mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Liver
CAUTION
Glibamet 5mg/850mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Glibamet 5mg/850mg Tablet may be needed. Please consult your doctor.
Glibamet 5mg/850mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Glibamet 5mg/850mg Tablet
₹4/Tablet
Glucored Forte 850 Tablet
Sun Pharmaceutical Industries Ltd
₹5.8/Tablet
45% costlier
₹3.65/Tablet
save 9%
Dilept 5mg/850mg Tablet
Zenox Pharmaceuticals Pvt Ltd
₹2.99/Tablet
save 25%
Clamet Forte Tablet
Essweil Pharma
₹3.4/Tablet
save 15%

Expert Advice

  • You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Glibamet 5mg/850mg Tablet.
  • Take it with food to lower your chance of having an upset stomach.
  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glibamet 5mg/850mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns

Questions Related to Glibamet

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I was diagnosed with type 2 diabetes in January and I m taking medicine. Now it's under control. Can you suggest me a meal plan that I can go for to control my weight and diabetes. Thank you
Dr. Shikha Mishra
Dietician
eat 6-7 meals per day, which consist fruits, nuts, buttermilk,egg, homecooked food. Drink 3-4 litters of water.Be active whole day for personalized diet chart write to me on shikhamishra.nutrition@gmail.com do minimum 45 min exercise everyday like yoga, cardio or weights
I have type 2 diabetes since 2 years. Since 6 months, my sugar level remains between 130-150. I take doctor prescribed Gluconorm tablet twice a day. Is it enough?
Dr. Sanjay Bhatt
Diabetes Specialist
I think you should follow diabatic diet chart which will help you to your sugar level in normal limit with tab. gluconorm
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FAQs

Q. What is Glibamet?

Glibamet is a combination of two medicines: Glibenclamide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glibenclamide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.

Q. What is type 2 diabetes?

Type 2 diabetes is the most common form of diabetes. It is a condition in which the body is unable to make enough insulin, and the insulin produced by the body does not work well. When this happens, the glucose level in the blood rises and leads to serious medical problems. Symptoms of high blood sugar include frequent urination, increased thirst and increased hunger. Diabetes, if not treated properly, can cause long-term complications like neuropathy (nerve damage), nephropathy (kidney damage), eye damage (retinopathy), foot problems and also a higher risk of developing heart diseases.

Q. What are the possible side effects of Glibamet?

The use of Glibamet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Q. Can the use of Glibamet cause hypoglycemia?

Yes, the use of Glibamet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with this medicine. So, regular monitoring of blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.

Q. Can the use of Glibamet lead to Vitamin B12 deficiency?

Yes, the use of Glibamet can cause vitamin B12 deficiency on long-term use as it interferes with the absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient may feel a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Q. Are there any specific conditions in which Glibamet should not to be taken?

The use of Glibamet should be avoided in patients with known allergy to any of the components or excipients of this medicine. It should also be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Glibamet?

No, it is not safe to take Glibamet along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Q. What are the instructions for storage and disposal of Glibamet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
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