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Genxtor Injection

Temsirolimus (25mg/ml)
Genuine
Authenticity Assured
Prescription
required
Genxtor Injection is used as a chemotherapy agent for the treatment of kidney cancer and mantle cell lymphoma (a type of cancer of lymph nodes immune cells). It works by blocking abnormal proteins that causes the multiplication of cancer cells. This helps in slowing the growth of tumors.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 31 Mar 2026 | 02:31 PM (IST)
₹45945 MRP ₹500008% off 
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General Information

Contains

Temsirolimus (25mg/ml)

Marketer

Biocon

Storage

Store below 30°C
The content is shown in English
Genxtor Injection image
Genxtor Injection image

Product introduction

Genxtor Injection is a prescription medicine that must be administered by a healthcare professional. You must receive the exact dose of it as per the prescription. An overdose of this medicine may have serious side effects on the body.

Some common side effects of this medicine include rash, weakness, nausea, edema, loss of appetite, anemia, increased glucose level in the blood,  increased blood lipid level, and increased alkaline phosphatase level in blood. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions such as rash, shortness of breath, coughing, and swelling.

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body.

Uses of Genxtor Injection

Benefits of Genxtor Injection

Treatment of Mantle-cell lymphoma
Mantle-cell lymphoma is a cancer of the white blood cells in our body, also called non-Hodgkin's lymphoma. White blood cells are those cells that help us to fight infections. Genxtor Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Side effects of Genxtor Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Genxtor
  • Rash
  • Weakness
  • Nausea
  • Edema (swelling)
  • Decreased white blood cell count
  • Increased glucose level in blood
  • Anemia (low number of red blood cells)
  • Loss of appetite
  • Increased blood lipid level
  • Increased alkaline phosphatase level in blood

How to use Genxtor Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Genxtor Injection works

Genxtor Injection is a kinase inhibitor. It shows its action by blocking the action of the abnormal protein that causes the multiplication of cancer cells. This may help slow the growth of tumors.

Quick tips

  • Genxtor Injection is given for the treatment of kidney cancer.
  • Genxtor Injection interferes with wound healing, so it is advisable to use with caution if you have any scheduled surgery.
  • Inform your doctor if you have diabetes as the use of Genxtor Injection might increase the level of blood sugar. Report excessive thirst or any increase in the volume or frequency of urination.
  • Report immediately for the occurrence of infections or any new or worsening abdominal pain or blood in their stools after using Genxtor Injection.
  • Your doctor will monitor your cholesterol level as Genxtor Injection might increase the level of serum triglycerides and cholesterol.
  • The use of live vaccines, and close contact with those who have received live vaccines, while on Genxtor Injection should be avoided.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Genxtor Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Genxtor Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Genxtor Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Genxtor Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Genxtor Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
Genxtor Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Genxtor Injection is not advised in some patients with moderate to severe liver disease.

Interaction with drugs

Taking Genxtor with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Everolimus (Oral Route)

Concurrent use should be avoided.
Severe

Aprepitant (Oral Route)

Please consult with your doctor. If safer alternative of Temsirolimus is not available, your doctor may adjust the dose.
Severe

Aprepitant (Injection Route)

Please consult with your doctor. If safer alternative of Temsirolimus is not available, your doctor may adjust the dose.
Severe

Atazanavir (Oral Route)

Please consult with your doctor. If safer alternative of Temsirolimus is not available, your doctor may adjust the dose.
Severe

Bosentan (Oral Route)

Please consult with your doctor. If suitable alternative of Temsirolimus is not available, your doctor may adjust the dose. Bosentan may reduce blood levels of active form of Temsirolimus.

Fact Box

Chemical Class

Macrolide lactams

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors

Related lab tests

Complete Blood Count

Cyclin D1

References

  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1743-45.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1325.
  3. Temsirolimus. Sandwich, Kent: Pfizer Limited; 2007 [revised Jan. 2019]. [Accessed 24 Jan. 2019] (online) Available from:
  4. Temsirolimus. Philadelphia, Pennsylvania: Wyeth Pharmaceuticals Inc.; 2007 [revised Apr. 2007]. [Accessed 06 Apr. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:
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User feedback

Others
50%
Kidney cancer
50%
Excellent
33%
Average
33%
Poor
33%
Vomiting
17%
Nausea
17%
Rash
17%
Headache
17%
Abdominal pain
17%
With food
50%
Empty stomach
50%
Expensive
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50%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Biocon
Address: 20th KM, Hosur Road, Electronic City, Bangalore, India - 560 100

Vendor Details

Country of origin: India

Lab tests offered by us

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