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Genpraz 20 mg Tablet

Macleods Pharmaceuticals Pvt Ltd

Composition for Genpraz 20 mg Tablet

Prescription Required

Primary uses of Genpraz 20 mg Tablet

Acidity, Peptic ulcer disease, Gastroesophageal reflux disease (Acid reflux)
Potentiallyunsafewith
Alcohol
DISCONTINUED
We do not sell this product at present

Medicine Overview of Genpraz Tablet

Uses of Genpraz Tablet

Genpraz 20 mg Tablet is used in the treatment of acidity, peptic ulcer disease and gastroesophageal reflux disease (acid reflux).

Genpraz Tablet side effects

Common

Side Effects of Genpraz are Vomiting, Headache, Stomach pain, Nausea, Flatulence, Diarrhoea.

How to use Genpraz Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Genpraz 20 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Genpraz Tablet works

Genpraz 20 mg Tablet is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

In Depth Information on Genpraz Tablet

Expert advice for Genpraz Tablet

  • Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
  • Genpraz 20 mg Tablet can decrease magnesium levels in blood. Get your magnesium levels checked regularly. You may need a magnesium supplement or need to discontinue your medicine. 
  • Inform your doctor if you are suffering from osteoporosis as Genpraz 20 mg Tablet can weaken your bones by decreasing calcium levels in blood. You may need a calcium supplement, preferably calcium citrate.
  • Genpraz 20 mg Tablet is a well-tolerated medicine and provides relief for a long time.
  • It may take a few days to show its effect. You can take an antacid for a quick relief during this time unless your doctor has asked you not to use them.
  • Once you start feeling better, do not stop taking your medicine. Take it for the duration as advised by your doctor
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Genpraz Tablet related warnings
Special precautions for Genpraz Tablet
Alcohol
CAUTION
Pregnancy
WEIGH RISKS VS BENEFITS
Genpraz 20 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Genpraz 20 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
Genpraz 20 mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Kidney
SAFE
Genpraz 20 mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Genpraz 20 mg Tablet is recommended.
Liver
Genpraz 20 mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Genpraz 20 mg Tablet may be needed. Please consult your doctor.

What if you miss a dose of Genpraz Tablet?uses

If you miss a dose of Genpraz 20 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions about Genpraz Tablet

Frequently asked questions about Rabeprazole

Q. Is Genpraz an over the counter product?
No, Genpraz is not an over the counter product, it is available when prescribed by a doctor.
Q. Is Genpraz an antacid?
Genpraz is not an antacid. It belongs to the class of proton pump inhibitors (PPIs) which decrease the amount of acid produced in the stomach while antacids only neutralize the stomach acid by coating the stomach.
Q. Does Genpraz cause osteoporosis (thinning of bones)?
Yes, long term use of Genpraz can cause osteoporosis (thinning of bones). It decreases the calcium absorption leading to calcium deficiency and increases the risk of bone fractures of hip, wrist or spine. Inform your doctor if you have osteoporosis or if you are taking corticosteroids (these can increase the risk of osteoporosis) before starting your therapy. Take enough calcium and vitamin D to reduce the risk.
Q. Can I take aluminum hydroxide and magnesium carbonate or other antacids with Genpraz?
Genpraz can be taken with antacids like aluminum hydroxide, magnesium carbonate or sodium bicarbonate. Genpraz takes a few days to show its effect, so antacids can be taken during that time for relief of acidity and heartburn. However, antacids should be taken two hours before or one hour after taking Genpraz as antacids can increase the pH of the stomach and decrease the action of Genpraz which requires a lower pH for its action.
Q. Does Genpraz have addictive potential?
No, Genpraz has no addictive potential. It shows no withdrawal symptoms when you stop using this medicine.
Q. Is Genpraz safe?
Yes, Genpraz is safe if taken for prescribed duration in prescribed doses as advised by your doctor. However, there are some very common side effects that you can experience at effective doses like nausea, abdominal pain, constipation, diarrhea, and flatulence.
Q. Does Genpraz cause hair loss?
No, hair loss has not been reported as a side effect of Genpraz. Talk to your doctor in case there is excessive hair fall as it could be due to some underlying problem that needs attention.
Q. Does Genpraz cause flatulence (gas or bloating)?
Flatulence (gas) has been reported as a common side effect of Genpraz. Although it would be mild to moderate in nature and transient.
Q. Does Genpraz cause tinnitus (ringing in the ears)?
Tinnitus (ringing sensation in the ears) has not been seen as a side effect with the use of Genpraz. Talk to your doctor in case you have this problem as it could be due to some underlying condition that needs attention.
Q. Does Genpraz cause weight gain?
Weight gain has been reported as a rare side effect of Genpraz. Weight gain can add to your problem of acidity and heartburn. So, you must try to do some exercise and make healthy changes in your diet to control your weight.
Q. Does Genpraz expire?
Yes, like any other medicine, Genpraz also expires. Always check the expiry date on the pack of the medicine before using it.
Q. Does Genpraz cause constipation?
Constipation is a common side effect seen in patients using Genpraz. Making healthy lifestyle changes like doing yoga, taking high fiber diet and plenty of fluids will prevent constipation.
Q. Does Genpraz cause high blood pressure?
Genpraz is not reported to cause high blood pressure. In case you experience high blood pressure, talk to your doctor as it may need attention. Common side effects seen with Genpraz includes nausea, abdominal pain, constipation, diarrhea, and flatulence.
Q. Does Genpraz cause headache?
Headache is reported as one of the common side effects of Genpraz. Please consult your doctor in case you experience an intolerable headache for a prolonged duration while taking Genpraz.
Q. Can I take Genpraz with ranitidine?
Yes, Genpraz can be taken with ranitidine. As Genpraz show its effect after some days, Ranitidine can be taken for immediate relief. No drug-drug interactions or change in side effect profile has been reported when they are used together compared to either drug alone.
Q. Can I take Genpraz with ibuprofen?
Genpraz can be taken with ibuprofen. Genpraz is used to prevent painkiller (NSAIDs) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.
Q. Can I take Genpraz with paracetamol?
Genpraz can be taken with paracetamol. Genpraz is used to prevent painkiller (NSAIDs) induced stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.
Q. How is Genpraz metabolized?
Genpraz is metabolized in the liver mainly by microsomal CYP450 enzymes (CYP2C19 and CYP3A4). Patients with poor CYP2C19 enzymatic activity will have higher levels of Genpraz for a long time and a better suppression of stomach acid.
Q. Can Genpraz be used for the treatment of throat infection?
No, Genpraz is not meant for throat infections. However, it may be given along with antibiotics and other drugs to protect the stomach from excessive acid secretion.
Q. Why is Genpraz used with cinitapride for some conditions?
Cinitapride increases the movement of the gut and is useful in the treatment of conditions like heartburn, dyspepsia and is also useful in the treatment of reflux esophagitis. It has much better efficacy when it is used with Genpraz.
Q. Does Genpraz play any role in treating ulcerative colitis?
Genpraz does not have any role in the treatment of ulcerative colitis. However, it can be given if there is associated dyspepsia or increased stomach acid secretion. Talk to your doctor before taking any treatment for ulcerative colitis.
Q. Can Genpraz be used for reflux esophagitis?
Yes, Genpraz is effective in the treatment of reflux esophagitis. It is a disease in which stomach acid or bile irritates and inflames the lining of the food pipe. Genpraz decreases the production of acid in the stomach and can help in healing the inflamed and eroded esophagus.The efficacy is better when it is given in combination with a prokinetic agent like domperidone.
Q. Is Genpraz being used for treating weight loss?
No, Genpraz is not used for the treatment of weight loss. It is a proton pump inhibitor and is used for the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers.
Q. Is there any role of Genpraz in treating hiatus hernia?
A hiatus hernia is the bulging of the stomach into the chest through an esophageal opening in the diaphragm which is larger than the normal size. A hiatus hernia is associated with acidity and heartburn. Genpraz does not play any role in treating hiatus hernia, however, it can help in relieving the symptoms of acidity, heartburn and acid reflux.
Q. Can I take Genpraz with vitamin D?
Yes, vitamin D can be taken with Genpraz. Vitamin D is generally advised to be taken as a supplement with Genpraz as its long-term use decreases the absorption of calcium and cause calcium deficiency. This can lead to osteoporosis (thinning of bones) and increase the risk of bone fractures like hip, wrist and spine fractures.
Q. How is Genpraz useful in the treatment of H. pylori?
Genpraz is used along with antibiotics for the treatment of H.Pylori infection. It works by decreasing stomach acid volume and decreasing breakdown and washout of antibiotics leading to an increased antibiotic concentration and tissue penetration. It also helps in the symptomatic relief by decreasing associated acidity, reflux, and heartburn.
Q. Can I take Genpraz with domperidone?
Genpraz can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone increases gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.
Q. Can long term use of Genpraz cause magnesium deficiency?
Long-term use of Genpraz can lower magnesium levels in patients taking multiple daily doses for a year or longer (at least 3 months). Get your magnesium levels checked at regular intervals. Tell your doctor if you experience seizures, dizziness, abnormal or fast heartbeat, jitteriness, jerking movements or shaking (tremors), muscle weakness, spasms of the hands and feet, cramps, muscle aches or spasm of the voice box.

Severely interacts with other drugs like

Taking Genpraz with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Genpraz with Cilostazol
LIFE-THREATENING
Medicines with composition Cilostazol: Pencil, Zilast, Stozic, Preclaud, Pletoz
Genpraz with Indinavir
LIFE-THREATENING
Medicines with composition Indinavir: Indivan
Genpraz with Ritonavir
LIFE-THREATENING
Medicines with composition Ritonavir: Viriton, Ritomune, Ritomax
Genpraz with Diazepam
SERIOUS
Medicines with composition Diazepam: Dizapam, Zeopse, Karpam, Osopose, Peptica, Placidox, Anxol, D P M
Genpraz with Midazolam
SERIOUS
Medicines with composition Midazolam: Medzol, Mezolam, Midfast, Fulsed, Midosed, Midzee, Benzosed
Genpraz with Sodium Bicarbonate
SERIOUS
Medicines with composition Sodium Bicarbonate: Sodamax, Sobinix, Sobimed, Soda Bicarb Glycerin
Genpraz with Clobazam
SERIOUS
Genpraz with Nitrazepam
SERIOUS
Medicines with composition Nitrazepam: Konit, Zipam, Enzed, Nitrosh, Nap, Nitraz, Nzm, Sopor, N Tra, Nira, Hypnoril, Nitab, Hypnocent
Genpraz with Magnesium Hydroxide
SERIOUS
Medicines with composition Magnesium Hydroxide: Mgmax
Genpraz with Flurazepam
SERIOUS
Medicines with composition Flurazepam: Nindral
Genpraz with Etizolam
SERIOUS
Genpraz with Lorazepam
SERIOUS
Genpraz with Chlordiazepoxide
SERIOUS
Medicines with composition Chlordiazepoxide: Equblam, Zepox, Raipox, Equiliser, Anxibrium, Poxid, Peaceoxide, Anxon H, Equilibrium, Cloxide, Librel
Genpraz with Methotrexate
MODERATE
Medicines with composition Methotrexate: Methosis, Metrex, Rhutrex, Meditrex, Mext, Trex, Vibzi, Meth
Genpraz with Dipyridamole
MODERATE
Medicines with composition Dipyridamole: Cardiwell, Thrombonil
Genpraz with Phenytoin
MODERATE
Medicines with composition Phenytoin: Stoin, Marantin, Notian, Phenytoin Sodium, Phenozed, Episol, Neptoin, C-Toin, Protoin, Pna, Seztin, Atoin, Phenos
Genpraz with Digoxin
MINOR
Medicines with composition Digoxin: Digon, Cardioxin
Genpraz with Spiramycin
MINOR
Medicines with composition Spiramycin: Spiramycin, Macromycin, Spiratox

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