Fos-Aprepitant 125mg Tablet is a prescription medicine used to prevent nausea and vomiting caused by chemotherapy. It is also used in the prevention of postoperative nausea and vomiting in adults.
Fos-Aprepitant 125mg Tablet is taken with or without food in a dose and duration as advised by the doctor. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are headache, hiccups, loss of appetite, fatigue, and constipation. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause diarrhea, so it is beneficial to drink plenty of fluids while taking this medicine as it may help to prevent dehydration. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Before taking this medicine, you should tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
Uses of Fos-Aprepitant Tablet
Nausea and vomiting due to chemotherapy
Benefits of Fos-Aprepitant Tablet
In Nausea and vomiting due to chemotherapy
Fos-Aprepitant 125mg Tablet is used to prevent nausea and vomiting caused by chemotherapy. It helps improve comfort during cancer treatment by blocking signals in the brain that trigger these symptoms, allowing patients to better tolerate their therapy.
Side effects of Fos-Aprepitant Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Fos-Aprepitant
Headache
Diarrhea
Dizziness
Hiccup
Loss of appetite
Fatigue
Constipation
How to use Fos-Aprepitant Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Fos-Aprepitant 125mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Fos-Aprepitant Tablet works
Fos-Aprepitant 125mg Tablet is an antiemetic medication. It works by blocking the action of a chemical messenger (neurokinin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy).
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Fos-Aprepitant 125mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Fos-Aprepitant 125mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Fos-Aprepitant 125mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Fos-Aprepitant 125mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Fos-Aprepitant 125mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Fos-Aprepitant 125mg Tablet is recommended.
Liver
SAFE IF PRESCRIBED
Fos-Aprepitant 125mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Fos-Aprepitant 125mg Tablet may not be needed in these patients. Please consult your doctor.
What if you forget to take Fos-Aprepitant Tablet?
If you miss a dose of Fos-Aprepitant 125mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Fos-Aprepitant 125mg Tablet helps prevent nausea and vomiting caused by certain chemotherapy medicines.
It will not help if you already have nausea and vomiting.
Do not use it continuously for a long time.
It is recommended to take Fos-Aprepitant 125mg Tablet 1 hour before chemotherapy treatment (Day 1) and in the morning on Days 2 and 3.
It may damage sperms and may harm the baby if used during pregnancy or breastfeeding.
Fact Box
Chemical Class
Phenylmorpholine Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Neurokinin-1 (NK1) Receptor Antagonists
Interaction with drugs
Taking Fos-Aprepitant with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Watch out for symptoms of Aprepitant side effects such as nausea, vomiting, headache, dizziness, constipation or weakness and consult your doctor if you experience them. They may a... More
My wife is 13 week pregnent her docter change her tablet from mvista to doxynate plus me I know the reason is both tablet aee same. Docter asked to taje doxynate plus 2 tablet at bed time.please suggest.
Dr. Megha Tuli
Obstetrics and Gynaecology
Doxynate is tablet to stop vomiting dear. It is ok to take them at bed time. It is widely recommended to take for nausea and vomiting of pregnancy.
I am in the first month of pregnancy and I am experiencing nausea, vomiting, stomach pain (moderate to severe) as well as discomfort. Current medications is Susten SR 200 (OD), Duvadilan retard (OD), Doxinate (BD), Folverine D (OD), Fertigyn 500 (1 amp weekly) and aciloc 150 (BD). What should I do to ease my situation. Please suggest
Dr. Suman Rao
Obstetrics and Gynaecology
The med suggested are to support of pregnancy and for acidity and nausea and vomiting. Continue the same. You can upgrade the med for vomiting after consulting your
Monitor temperature of Patient. If Patient has fever place a cool, damp washcloth on your child's forehead. Give your Patient a lukewarm tub bath or a sponge bath. Give a sponge bath as follows: - ? Use lukewarm water [90?F (32.2?C) to 95?F (35?C)]. Do not use cold water, ice, or rubbing alcohol, which will lower the child's body temperature too quickly. ? Sponge for 20 to 30 minutes. ? Stop if the child starts to shiver. If your child doesn't like the sponge bath or doesn't feel better after the bath, there is no need to give another one. You can use paracetamol also along with above measures to control fever till you consult Dr. will determine underlying disorders by clinical examination which range from mild conditions to the most serious of bacterial and viral illnesses and will prescribe medicines accordingly. Advice given without doing clinical examination can be imperfect or some time harmful to patient.
What are Fos-Aprepitant 125mg Tablet capsules/ what is Fos-Aprepitant 125mg Tablet used for?
Fos-Aprepitant 125mg Tablet is used in adults in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (cancer treatment) or in some cases after a surgery
How does Fos-Aprepitant 125mg Tablet work?
Fos-Aprepitant 125mg Tablet is an antiemetic that works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.
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References
McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1086.
Aprepitant. [Accessed 28 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
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