Fibronib 100 Capsule

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 19 Jan 2026 | 02:04 AM (IST)

Fibronib 100 Capsule is used in the treatment of idiopathic pulmonary fibrosis and non-small cell lung cancer. It works by targeting certain pathways involved in the growth and progression of these diseases and helps to stop or slow the spread of cancer cells.

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Cold stored

Stored between 2-8°C

₹640 MRP ₹703.139% off

Fibronib 100 Capsule is currently sold out

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NIntabID 100mg Capsule

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Fibronib 100 Capsule

strip of 10 capsules

₹640

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Same composition

NIntabID 100mg Capsule

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Nintedanib (100mg)

by J B Chemicals and Pharmaceuticals Ltd

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General Information

Contains

Nintedanib (100mg)

Marketer

Chemo Healthcare Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Fibronib 100 Capsule should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Diarrhea is a very common side effect of this medicine. You are advised to drink plenty of fluids and inform your doctor if it does not go away. Other common side effects include nausea, abdominal pain, vomiting, abnormal liver function tests, loss of appetite, headache, weight loss, and high blood pressure. Your doctor might ask you for some blood tests to monitor liver functioning.

Before taking it, tell your doctor if have a bleeding problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Fibronib Capsule

Benefits of Fibronib Capsule

Treatment of Idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis is a lung disease caused by lung tissue becoming thick and stiff and eventually forming scar tissue within the lungs. The scarring, or fibrosis, seems to result from a cycle of damage and healing that occurs in the lungs. These changes are irreversible and the affected person may experience shortness of breath or dry cough as initial symptoms. Fibronib 100 Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You may experience some bothersome side effects. Discuss with your doctor if you have any doubts.

Treatment of Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Fibronib 100 Capsule helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Fibronib Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Fibronib

Diarrhea
Nausea
Abnormal liver function tests
Loss of appetite
Headache
Weight loss
High blood pressure
Vomiting
Abdominal pain

How to use Fibronib Capsule

Take this medicine in the dose and duration as advised by your doctor. Fibronib 100 Capsule should be taken with or after food.

How Fibronib Capsule works

Fibronib 100 Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. It also blocks pathways in the body that result in fibrosis, which is the thickening or scarring of the tissue. This helps to stop or slow the spread of cancer cells.

All substitutes for Fibronib 100 Capsule

For information purposes only. Consult a doctor before taking any medicine.

NIntabID 100mg Capsule

by J B Chemicals and Pharmaceuticals Ltd

₹78.2/capsule

22% costlier

Quick tips

Take it with food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Fibronib 100 Capsule. Please consult your doctor.

Pregnancy

UNSAFE

Fibronib 100 Capsule is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Fibronib 100 Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Fibronib 100 Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Fibronib 100 Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
There is limited information available on the use of Fibronib 100 Capsule in these patients.

Liver

CAUTION

Fibronib 100 Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.
Please consult your doctor. Use of Fibronib 100 Capsule is not recommended in patients with moderate to severe liver disease.

Interaction with drugs

Taking Fibronib with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Carbamazepine (Oral Route)

Do not consume Nintedanib with Carbamazepine. Carbamazepine may reduce blood levels of Nintedanib.

Severe

Phenytoin (Oral Route)

Do not consume Nintedanib with Phenytoin. Phenytoin may reduce blood levels of Nintedanib.

Severe

Phenytoin (Injection Route)

Do not consume Nintedanib with Phenytoin. Phenytoin may reduce blood levels of Nintedanib.

Severe

Rifampicin (Oral Route)

Do not consume Nintedanib with Rifampicin. Rifampicin may reduce blood levels of Nintedanib.

Severe

Rifampicin (Injection Route)

Do not consume Nintedanib with Rifampicin. Rifampicin may reduce blood levels of Nintedanib.

Frequently asked questions

What is Fibronib 100 Capsule used for?

Fibronib 100 Capsule is a medication that helps slow down scarring or stiffness in the lungs. It is mainly used to treat conditions like pulmonary fibrosis (lung scarring) and certain types of lung diseases. It works by blocking substances in your body that cause lung tissues to become thick and stiff. Fibronib 100 Capsule helps slow down lung function decline, but it is not a cure.

Can Fibronib 100 Capsule cause serious health problems?

Yes, though rare, Fibronib 100 Capsule may cause liver injury, heart attack, bleeding problems, kidney issues (protein in urine) and gastrointestinal perforation. Your doctor will monitor you regularly to reduce these risks.

Is Fibronib 100 Capsule safe for people with liver or kidney problems?

Fibronib 100 Capsule is not recommended for moderate or severe liver disease. In mild cases, the dose is usually reduced. Fibronib 100 Capsule should also be used with caution in kidney impairment, and monitoring is essential.

Who should avoid taking Fibronib 100 Capsule?

Fibronib 100 Capsule should be avoided in individuals if they are pregnant or planning pregnancy, have severe liver problems, have had recent stomach surgery or are at high risk of bleeding or blood clots. There are no official contraindications, but caution is advised in these specific groups.

What should I do if I get diarrhea while on Fibronib 100 Capsule?

Diarrhea is common during Fibronib 100 Capsule treatment. Your doctor may advise using anti-diarrheal medicine early. Drink fluids and contact your doctor if it is severe or long-lasting, as they may adjust your dose.

Can Fibronib 100 Capsule reverse lung damage?

No, Fibronib 100 Capsule does not reverse fibrosis (lung scarring), but it slows its progression, helping to preserve lung function and potentially improve quality of life over time.

What foods should I avoid while taking Fibronib 100 Capsule?

While there are not specific foods you should avoid, eating a light meal when taking Fibronib 100 Capsule can help reduce stomach upset. If you experience diarrhea, avoid spicy, fatty, or junk foods that might make it worse.

How long does it take for Fibronib 100 Capsule to work?

Fibronib 100 Capsule works gradually to slow down lung scarring. It is not a quick-relief medication, and it may take several weeks or months before you notice improvements. Your doctor will monitor your progress through regular check-ups and tests.

When should I contact my doctor while taking Fibronib 100 Capsule?

Contact your doctor immediately if you experience severe diarrhea that does not improve, unusual bleeding or bruising, severe stomach pain, yellowing of skin or eyes, dark urine and fever with infection symptoms.

Fact Box

Chemical Class

Indolecarboxylic acids

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

References

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Chemo Healthcare Pvt Ltd
Address: plot no : 1, new ahmedabad indl. estate, vill. morraiya, tal, sanand rd, changodar, gujarat 382213

Vendor Details

Country of origin: India

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Fibronib 100 Capsule

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Fibronib Capsule

Benefits of Fibronib Capsule

Side effects of Fibronib Capsule

How to use Fibronib Capsule

How Fibronib Capsule works

All substitutes for Fibronib 100 Capsule

NIntabID 100mg Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Carbamazepine (Oral Route)

Phenytoin (Oral Route)

Phenytoin (Injection Route)

Rifampicin (Oral Route)

Rifampicin (Injection Route)

Frequently asked questions

What is Fibronib 100 Capsule used for?

Can Fibronib 100 Capsule cause serious health problems?

Is Fibronib 100 Capsule safe for people with liver or kidney problems?

Who should avoid taking Fibronib 100 Capsule?

What should I do if I get diarrhea while on Fibronib 100 Capsule?

Can Fibronib 100 Capsule reverse lung damage?

What foods should I avoid while taking Fibronib 100 Capsule?

How long does it take for Fibronib 100 Capsule to work?

When should I contact my doctor while taking Fibronib 100 Capsule?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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