Feroxamine 400mg Injection

Deferoxamine (400mg)

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Feroxamine 400mg Injection is a medicine used in the treatment of chronic iron overload caused due to frequent blood transfusion. It helps in removing the excess iron from the body and reduces the risk of it causing organ damage.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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Gurgaon

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General Information

Contains

Deferoxamine (400mg)

Marketer

Novartis India Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Feroxamine 400mg Injection is generally administered by a healthcare professional. You should not self-administer this medicine.

Using of Feroxamine 400mg Injection may cause few side effects such as flushing (a sense of warmth in the face, ears, neck and trunk), rash, decreased blood pressure and abdominal pain. If the side effects persist or worsen, inform your doctor.

Uses of Feroxamine Injection

Benefits of Feroxamine Injection

Iron overload
Iron overload is a condition where iron accumulates in the body due to repeated transfusions or certain medical conditions. If left unmanaged, it can damage the liver, heart, and other organs. Feroxamine 400mg Injection helps reduce iron levels in the body, lowering the risk of long-term complications and supporting organ health.

Transfusion dependent thalassemia
Transfusion-dependent thalassemia is a blood disorder where the body cannot make enough healthy red blood cells, leading to severe anemia. To manage this, patients require frequent blood transfusions, which gradually lead to a buildup of excess iron in the body. Feroxamine 400mg Injection helps by binding to this excess iron and removing it through urine and stool. This supports safe long-term transfusion therapy by preventing iron from harming vital organs.

Side effects of Feroxamine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Feroxamine

Flushing (sense of warmth in the face, ears, neck and trunk)
Rash
Decreased blood pressure
Abdominal pain

How to use Feroxamine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Feroxamine Injection works

Feroxamine 400mg Injection traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.

Quick tips

Feroxamine 400mg Injection is used to reduce excess iron from the body.
Feroxamine 400mg Injection may cause your urine to turn a red/brown color. This is the iron being removed from your body and is nothing for you to worry about as it is quite harmless.
If you are taking any antacid, take them 2 hours before or after Feroxamine 400mg Injection.
Feroxamine 400mg Injection may cause dizziness. It is advisable not to drive or operate any machinery until you feel normal again.
Inform your doctor if you have any liver or kidney disease.
Inform your doctor if you are pregnant or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Feroxamine 400mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Feroxamine 400mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Feroxamine 400mg Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

UNSAFE

Feroxamine 400mg Injection may cause side effects that could affect your ability to drive.
If you experience dizziness or other central nervous disturbances, or impairment of vision with the use of Feroxamine 400mg Injection then you should refrain from driving a vehicle.

Kidney

CAUTION

Feroxamine 400mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Feroxamine 400mg Injection is not recommended in patients with severe kidney disease.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Feroxamine 400mg Injection in patients with liver disease.

Interaction with drugs

Taking Feroxamine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Prochlorperazine (Oral Route)

If concurrent use is essential, please consult your doctor. Prochlorperazine may increase the side effects of Deferoxamine.

Moderate

Prochlorperazine (Injection Route)

If concurrent use is essential, please consult your doctor. Prochlorperazine may increase the side effects of Deferoxamine.

Fact Box

Chemical Class

Acetohydroxamic acids

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Iron Chelators

Related lab tests

Iron Serum

Iron Studies

Total Iron Binding Capacity

References

Byrns MC, Penning TM. Environmental Toxicology: Carcinogens and Heavy Metals. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1875-76.
Kosnett MJ. Heavy Metal Intoxication & Chelators. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1010.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 365-66.
Deferoxamine. Stein, Switzerland: Novartis Pharma Stein AG; 2011. [Accessed 6 Apr. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Feroxamine 400mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Feroxamine Injection

Benefits of Feroxamine Injection

Side effects of Feroxamine Injection

How to use Feroxamine Injection

How Feroxamine Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Prochlorperazine (Oral Route)

Prochlorperazine (Injection Route)

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Iron Serum

Iron Studies

Total Iron Binding Capacity

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests