Deferoxamine is used in the treatment of iron overload and transfusion dependent thalassemia
How it works
Deferoxamine has a high affinity for ferric iron and forms chelates or stable water-soluble complexes with iron and other trivalent metal ions eg, aluminum. It removes free and bound iron from haemosiderin and ferritin, increasing the excretion of iron in urine and bile.
Common side effects
Allergic reaction, Fever, Abdominal pain, Leg cramps, Tachycardia, Difficulty in urination, Diarrhoea