Prochlorperazine is used in nausea, vomiting, migraine, vertigo and short term anxiety.

Prochlorperazine is a dopamine antagonist. Dopamine controls the region in the brain that causes nausea and vomiting and this medicine blocks the action of dopamine. Therefore, Prochlorperazine shows an antiemetic action. Prochlorperazine suppresses the vestibular apparatus in the inner ear and stops vertigo. The mechanism of action by which neuroleptics like prochlorperazine relieve headache is probably related to the dopamine D2 receptor antagonist. It has an antipsychotic effect by blocking the action of dopamine, which also affects thoughts and mood. So, it also helps to relieve short-term anxiety as well.

Dystonia (involuntary muscle contractions), Akathisia (inability to stay still), Parkinsonism, Tardive dyskinesia, Insomnia (difficulty in sleeping), Agitation, Convulsion