Ethomid Tablet

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 14 Apr 2026 | 04:20 PM (IST)

Ethomid Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment and prevention of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.

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General Information

Contains

Ethionamide (250mg)

Marketer

Macleods Pharmaceuticals Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Ethomid Tablet is usually given in combination with at least one other tuberculosis medicine. It is used in cases where bacteria have developed resistance to other antibacterial medicines. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at the same time every day. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and in the development of drug-resistant tuberculosis. This can lead to serious health complications.

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.

Some people may experience loss of appetite, nausea, vomiting, gastric irritation (inflammation of the stomach lining) and sudden lowering of blood pressure on standing (orthostatic hypotension), as side effects of this medicine. Please consult your doctor if these side effects worry you or do not get better.

Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. Your doctor may monitor your liver function, vision, and thyroid function while on treatment with this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Ethomid Tablet

Tuberculosis (TB)

Benefits of Ethomid Tablet

Tuberculosis (TB)
Ethomid Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Ethomid Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ethomid

Loss of appetite
Nausea
Vomiting
Gastric irritation
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Weakness
Depression
Sleepiness

How to use Ethomid Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ethomid Tablet may be taken with or without food.

How Ethomid Tablet works

Ethomid Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

Quick tips

Ethomid Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
It has to be taken for several months in order for it work properly (usually 6 months).
Take it with food to avoid stomach upset.
It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
Avoid consuming alcohol while taking this medication.
Do not stop taking Ethomid Tablet even if you start to feel better. Stopping early can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Ethomid Tablet.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Ethomid Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Ethomid Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Ethomid Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Ethomid Tablet may cause side effects such as drowsiness or a headache, that can impair your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Ethomid Tablet in patients with kidney disease. Please consult your doctor.
Dose adjustment may be needed in patients with end stage kidney disease.

Liver

UNSAFE

Ethomid Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Ethomid Tablet is not recommended in patients with the severe liver disease.

Interaction with drugs

Taking Ethomid with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Cycloserine (Oral Route)

Careful consideration is advised when taking Cycloserine with Ethionamide. If concurrent use is essential, watch out for symptoms such as impaired movements, dizziness or drowsiness and consult your doctor if you experience them. Ethionamide may reduce blood levels of Cycloserine.

Moderate

Isoniazid (Oral Route)

Caution is advised when taking Isoniazid with Ethionamide. If concurrent use is essential, please consult your doctor. Ethionamide may reduce blood levels of Isoniazid.

Frequently asked questions

What is Ethomid Tablet? What is it used for?

Ethomid Tablet is an antibiotic. It is used as a second-line medicine in combination with other anti-tuberculosis medicines for the treatment of all forms of tuberculosis caused by Mycobacterium tuberculosis.

Why is Ethomid Tablet called a second line drug?

Tuberculosis (TB) is a difficult infection to treat and when it is detected for the first time, first-line drugs are used. Generally, the appropriate use of first-line drugs (e.g. isoniazid, rifampicin, ethambutol, pyrazinamide, and streptomycin) can effectively cure TB. But, if the patient does not respond to first-line medicines, then second-line medicines (e.g. Ethomid Tablet, kanamycin, ciprofloxacin, etc.) are used. Second-line medicines have more side effects and are the second choice in terms of effectiveness.

Are there any precautions that I should take while taking Ethomid Tablet so that I respond to the treatment?

It is very important that you take the medicine exactly as directed by your doctor. Your doctor will prescribe at least two more medicines to be taken with Ethomid Tablet. Take all the prescribed medicines as per the instructions and do not miss or stop the treatment on your own. Missing doses and stopping the treatment without consulting the doctor are the major causes of treatment failure and drug resistance (not responding to the medication).

For how long do I need to take Ethomid Tablet?

Your doctor will decide the duration of your treatment depending upon your response to the treatment. The doctor will observe your maximum improvement by evaluating you clinically as well as your blood tests.

Why has my doctor asked me to get blood tests done regularly?

The blood tests are done to check if your liver is functioning properly or not, since Ethomid Tablet may affect your liver. Ethomid Tablet can also alter your blood glucose levels and thyroid hormone levels. Therefore, monitoring is required.

What are the symptoms which are suggestive of liver toxicity caused by Ethomid Tablet?

If you develop symptoms such as loss of appetite, nausea, jaundice (yellowing of the skin and eye white), dark urine, discolored stools, pain and tenderness in the upper right abdomen, inform your doctor immediately. These could be the signs of liver toxicity.

Is it necessary to take pyridoxine with Ethomid Tablet?

Pyridoxine is vitamin B6 that helps to prevent nerve damage, which may occur with the use of Ethomid Tablet. The symptoms of nerve damage are numbness, tingling, or pain in your hands or feet.

My friend is taking Ethomid Tablet and other medicines for TB. I have noticed that sometimes she acts very aggressively. Is it because of the disease or the treatment?

These changes could be due to Ethomid Tablet or other medicines that she is taking for TB. Ethomid Tablet may cause depression, confusion, aggression, abnormal thinking, and even hallucinations. You should speak to her family or doctor and help her out.

Fact Box

Chemical Class

Pyridine derivative

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Mycobacterial cell wall inhibitors-Ethambutol

Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

References

Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1561-562.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 513-14.
Ethionamide. Philadelphia, PA: Wyeth Pharmaceuticals Inc.; 2016. [Accessed 19 Jun. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:

User feedback

Patients taking Ethomid Tablet

Once A Day

100%

What are you using Ethomid Tablet for?

Tuberculosis (TB)

89%

Others

11%

How much was the improvement?

Excellent

52%

Average

48%

What were the side-effects while using Ethomid Tablet?

Loss of appetite

29%

Nausea

29%

Gastric irritation

29%

No Side Effect

14%

How do you take Ethomid Tablet?

Empty stomach

67%

With food

33%

Please rate Ethomid Tablet on price

Expensive

58%

Average

42%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Vendor Details

Country of origin: India

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Ethomid Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Ethomid Tablet

Benefits of Ethomid Tablet

Side effects of Ethomid Tablet

How to use Ethomid Tablet

How Ethomid Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cycloserine (Oral Route)

Isoniazid (Oral Route)

Frequently asked questions

What is Ethomid Tablet? What is it used for?

Why is Ethomid Tablet called a second line drug?

Are there any precautions that I should take while taking Ethomid Tablet so that I respond to the treatment?

For how long do I need to take Ethomid Tablet?

Why has my doctor asked me to get blood tests done regularly?

What are the symptoms which are suggestive of liver toxicity caused by Ethomid Tablet?

Is it necessary to take pyridoxine with Ethomid Tablet?

My friend is taking Ethomid Tablet and other medicines for TB. I have noticed that sometimes she acts very aggressively. Is it because of the disease or the treatment?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

References

User feedback

Patients taking Ethomid Tablet

What are you using Ethomid Tablet for?

How much was the improvement?

What were the side-effects while using Ethomid Tablet?

How do you take Ethomid Tablet?

Please rate Ethomid Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

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Lab tests offered by us

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