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Last updated:
18 Feb 2020 | 05:25 PM (IST)
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Ethiobin 250mg Tablet

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Overview

Introduction

Ethiobin 250mg Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment and prevention of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.

Ethiobin 250mg Tablet is usually given in combination with at least one other tuberculosis medicine. It is used in cases where bacteria have developed resistance to other antibacterial medicines. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at the same time every day. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and in the development of drug-resistant tuberculosis. This can lead to serious health complications.

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.

Some people may experience loss of appetite, nausea, vomiting, gastric irritation (inflammation of the stomach lining) and sudden lowering of blood pressure on standing (orthostatic hypotension), as side effects of this medicine. Please consult your doctor if these side effects worry you or do not get better.

Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. Your doctor may monitor your liver function, vision, and thyroid function while on treatment with this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Ethiobin Tablet

Side effects of Ethiobin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ethiobin

  • Loss of appetite
  • Nausea
  • Vomiting
  • Gastric irritation
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Weakness
  • Depression
  • Sleepiness

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Loss of appetite
    It is important to eat, even if you do not feel like it. You might try switching to smaller meals and frequent snacks. Try eating healthy and nutritious snacks that are high in calories and protein, such as dried fruit and nuts. It is important to drink even if you cannot eat. But, do not fill your stomach with liquid before eating. Eat when you are most hungry. Exercise such as a short walk may also increase your appetite. Talk to your doctor about possible medication or supplements if your condition does not improve.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Weakness
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.
  • Coping with Depression
    It is important to talk to your doctor if you think you may be depressed. The sooner you do this, the sooner you can recover. Treatment for depression can involve a combination of lifestyle changes, talking therapies (such as counseling and cognitive behavioral therapy) and medicines (antidepressants). There are many things you can do for yourself if your depression is not too severe. Exercise is an extremely effective treatment for depression, so make sure you keep as active as possible. It can really lift your mood. A healthy diet can also make a big difference to your mood (as well as improving your physical health). Mindfulness is a technique that many people find helpful. It may be tempting to smoke or drink alcohol, but both will make things worse in the long run. Try talking to a friend or family member even if you do not feel comfortable doing this. Get into a routine with regular sleep patterns and meals. If you have thoughts of self-harm or suicide, contact your doctor immediately.
  • Coping with Sleepiness
    If the medicine is making you drowsy during the day, stop what you are doing and sit or lie down until you feel better. You can also consider taking a nap. Physical exercises such as walking may be helpful. Do not drink alcohol, as it will make you feel more tired. Avoid driving or operating heavy equipment when you are feeling drowsy. This problem usually goes away as your body gets used to the medicine. However, if it does not, ask your doctor if you can take your medicine at bedtime or whether the dose can be reduced.

How to use Ethiobin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ethiobin 250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Ethiobin Tablet works

Ethiobin 250mg Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Ethiobin 250mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Ethiobin 250mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Ethiobin 250mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Ethiobin 250mg Tablet may cause side effects which could affect your ability to drive.
Ethiobin 250mg Tablet may cause side effects such as drowsiness or a headache, that can impair your ability to drive.
Kidney
SAFE IF PRESCRIBED
Ethiobin 250mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Ethiobin 250mg Tablet may not be needed in these patients. Please consult your doctor.
Dose adjustment may be needed in patients with end stage kidney disease.
Liver
CAUTION
Ethiobin 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Ethiobin 250mg Tablet may be needed. Please consult your doctor.
Use of Ethiobin 250mg Tablet is not recommended in patients with the severe liver disease.

What if you forget to take Ethiobin Tablet?

If you miss a dose of Ethiobin 250mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Ethiobin 250mg Tablet
₹11.19/Tablet
Thiomid E 250mg Tablet
United Biotech Pvt Ltd
₹12.65/Tablet
13% costlier
Ethomid Tablet
Macleods Pharmaceuticals Pvt Ltd
₹15.16/Tablet
35% costlier
Myobid 250 Tablet
Panacea Biotec Ltd
₹16.04/Tablet
43% costlier
Ethio 250mg Tablet
Concept Pharmaceuticals Ltd
₹16.5/Tablet
47% costlier
Ethide Tablet
Lupin Ltd
₹17.25/Tablet
54% costlier

Quick Tips

  • Ethiobin 250mg Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
  • It has to be taken for several months in order for it work properly (usually 6 months).
  • Take it with food to avoid stomach upset.
  • It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
  • Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
  • Avoid consuming alcohol while taking this medication.
  • Do not stop taking Ethiobin 250mg Tablet even if you start to feel better. Stopping early can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.

Fact Box

Chemical Class
Nicotinic acid derivatives
Habit Forming
No

Patient Concerns

arrow
My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
Though took vaccines in childhood, the test for TB came positive. Was advised to undergo treatment.physically absolute fit and healthy, is it advisable to take treatment?
Dr. Anshum Aneja Arora
Pulmonology
If sputum is positive for Tb , treatment is absolutely essential. Read more at www.arohealth.com/tuberculosis
arrow
Do you have any questions related to Ethiobin 250mg Tablet ?

User Feedback


FAQs

Q. What is Ethiobin? What is it used for?

Ethiobin is an antibiotic. It is used as a second-line medicine in combination with other anti-tuberculosis medicines for the treatment of all forms of tuberculosis caused by Mycobacterium tuberculosis.

Q. Why is Ethiobin called a second line drug?

Tuberculosis (TB) is a difficult infection to treat and when it is detected for the first time, first-line drugs are used. Generally, the appropriate use of first-line drugs (e.g. isoniazid, rifampicin, ethambutol, pyrazinamide, and streptomycin) can effectively cure TB. But, if the patient does not respond to first-line medicines, then second-line medicines (e.g. Ethiobin, kanamycin, ciprofloxacin, etc.) are used. Second-line medicines have more side effects and are the second choice in terms of effectiveness.

Q. Are there any precautions that I should take while taking Ethiobin so that I respond to the treatment?

It is very important that you take the medicine exactly as directed by your doctor. Your doctor will prescribe at least two more medicines to be taken with Ethiobin. Take all the prescribed medicines as per the instructions and do not miss or stop the treatment on your own. Missing doses and stopping the treatment without consulting the doctor are the major causes of treatment failure and drug resistance (not responding to the medication).

Q. For how long do I need to take Ethiobin?

Your doctor will decide the duration of your treatment depending upon your response to the treatment. The doctor will observe your maximum improvement by evaluating you clinically as well as your blood tests.

Q. Why has my doctor asked me to get blood tests done regularly?

The blood tests are done to check if your liver is functioning properly or not, since Ethiobin may affect your liver. Ethiobin can also alter your blood glucose levels and thyroid hormone levels. Therefore, monitoring is required.

Q. What are the symptoms which are suggestive of liver toxicity caused by Ethiobin?

If you develop symptoms such as loss of appetite, nausea, jaundice (yellowing of the skin and eye white), dark urine, discolored stools, pain and tenderness in the upper right abdomen, inform your doctor immediately. These could be the signs of liver toxicity.

Q. Is it necessary to take pyridoxine with Ethiobin?

Pyridoxine is vitamin B6 that helps to prevent nerve damage, which may occur with the use of Ethiobin. The symptoms of nerve damage are numbness, tingling, or pain in your hands or feet.

Q. My friend is taking Ethiobin and other medicines for TB. I have noticed that sometimes she acts very aggressively. Is it because of the disease or the treatment?

These changes could be due to Ethiobin or other medicines that she is taking for TB. Ethiobin may cause depression, confusion, aggression, abnormal thinking, and even hallucinations. You should speak to her family or doctor and help her out.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1561-562.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 513-14.
  3. Ethionamide. Philadelphia, PA: Wyeth Pharmaceuticals Inc.; 2016. [Accessed 19 Jun. 2019] (online) Available from:External Link
  4. Ethionamide. Hosur, India: Micro Labs Limited; 2017. [Accessed 19 Jun. 2019] (online) Available from:External Link
  5. Drugs.com. Ethionamide. [Accessed 01 Apr. 2019] (online) Available from:External Link
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

4, Lady Desika Road, Chennai – 600004., Tamil Nadu, India.
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We do not facilitate sale of this product at present

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