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Ethiobin 250mg Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Ethiobin 250mg Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment and prevention of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.
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General Information

Contains

Ethionamide (250mg)

Marketer

Medispan Ltd

Storage

Store below 30°C
The content is shown in English
Ethiobin 250mg Tablet image
Ethiobin 250mg Tablet image

Product introduction

Ethiobin 250mg Tablet is usually given in combination with at least one other tuberculosis medicine. It is used in cases where bacteria have developed resistance to other antibacterial medicines. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at the same time every day. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and in the development of drug-resistant tuberculosis. This can lead to serious health complications.

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.

Some people may experience loss of appetite, nausea, vomiting, gastric irritation (inflammation of the stomach lining) and sudden lowering of blood pressure on standing (orthostatic hypotension), as side effects of this medicine. Please consult your doctor if these side effects worry you or do not get better.

Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. Your doctor may monitor your liver function, vision, and thyroid function while on treatment with this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Ethiobin Tablet

Benefits of Ethiobin Tablet

Tuberculosis (TB)
Ethiobin 250mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Ethiobin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ethiobin
  • Loss of appetite
  • Nausea
  • Vomiting
  • Gastric irritation
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Weakness
  • Depression
  • Sleepiness

How to use Ethiobin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ethiobin 250mg Tablet may be taken with or without food.

How Ethiobin Tablet works

Ethiobin 250mg Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

Quick tips

  • Ethiobin 250mg Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
  • It has to be taken for several months in order for it work properly (usually 6 months).
  • Take it with food to avoid stomach upset.
  • It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
  • Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
  • Avoid consuming alcohol while taking this medication.
  • Do not stop taking Ethiobin 250mg Tablet even if you start to feel better. Stopping early can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Ethiobin 250mg Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Ethiobin 250mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Ethiobin 250mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Ethiobin 250mg Tablet may cause side effects that could affect your ability to drive.
Ethiobin 250mg Tablet may cause side effects such as drowsiness or a headache, that can impair your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Ethiobin 250mg Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Dose adjustment may be needed in patients with end stage kidney disease.
Liver

Liver

CAUTION
Ethiobin 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Ethiobin 250mg Tablet is not recommended in patients with the severe liver disease.

Interaction with drugs

Taking Ethiobin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Cycloserine (Oral Route)

Careful consideration is advised when taking Cycloserine with Ethionamide. If concurrent use is essential, watch out for symptoms such as impaired movements, dizziness or drowsiness and consult your doctor if you experience them. Ethionamide may reduce blood levels of Cycloserine.
Moderate

Isoniazid (Oral Route)

Caution is advised when taking Isoniazid with Ethionamide. If concurrent use is essential, please consult your doctor. Ethionamide may reduce blood levels of Isoniazid.

Frequently asked questions

Ethiobin 250mg Tablet is an antibiotic. It is used as a second-line medicine in combination with other anti-tuberculosis medicines for the treatment of all forms of tuberculosis caused by Mycobacterium tuberculosis.
Tuberculosis (TB) is a difficult infection to treat and when it is detected for the first time, first-line drugs are used. Generally, the appropriate use of first-line drugs (e.g. isoniazid, rifampicin, ethambutol, pyrazinamide, and streptomycin) can effectively cure TB. But, if the patient does not respond to first-line medicines, then second-line medicines (e.g. Ethiobin 250mg Tablet, kanamycin, ciprofloxacin, etc.) are used. Second-line medicines have more side effects and are the second choice in terms of effectiveness.
It is very important that you take the medicine exactly as directed by your doctor. Your doctor will prescribe at least two more medicines to be taken with Ethiobin 250mg Tablet. Take all the prescribed medicines as per the instructions and do not miss or stop the treatment on your own. Missing doses and stopping the treatment without consulting the doctor are the major causes of treatment failure and drug resistance (not responding to the medication).
Your doctor will decide the duration of your treatment depending upon your response to the treatment. The doctor will observe your maximum improvement by evaluating you clinically as well as your blood tests.
The blood tests are done to check if your liver is functioning properly or not, since Ethiobin 250mg Tablet may affect your liver. Ethiobin 250mg Tablet can also alter your blood glucose levels and thyroid hormone levels. Therefore, monitoring is required.
If you develop symptoms such as loss of appetite, nausea, jaundice (yellowing of the skin and eye white), dark urine, discolored stools, pain and tenderness in the upper right abdomen, inform your doctor immediately. These could be the signs of liver toxicity.
Pyridoxine is vitamin B6 that helps to prevent nerve damage, which may occur with the use of Ethiobin 250mg Tablet. The symptoms of nerve damage are numbness, tingling, or pain in your hands or feet.
These changes could be due to Ethiobin 250mg Tablet or other medicines that she is taking for TB. Ethiobin 250mg Tablet may cause depression, confusion, aggression, abnormal thinking, and even hallucinations. You should speak to her family or doctor and help her out.

Fact Box

Chemical Class

Pyridine derivative

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Mycobacterial cell wall inhibitors-Ethambutol

Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1561-562.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 513-14.
  3. Ethionamide. Philadelphia, PA: Wyeth Pharmaceuticals Inc.; 2016. [Accessed 19 Jun. 2019] (online) Available from:
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:
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User feedback

Tuberculosis (TB)
100%
Average
100%
Loss of appetite
50%
Orthostatic hypotension (sudden lowering of blood pressure on standing)
50%
With food
100%
Average
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Medispan Ltd
Address: 4, Lady Desika Road, Chennai – 600004., Tamil Nadu, India.

Vendor Details

Country of origin: India

Lab tests offered by us

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