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Enzyl 80 Capsule

Enzalutamide (80mg)

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Enzyl 80 Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 14 Mar 2026 | 02:58 AM (IST)

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General Information

Contains

Enzalutamide (80mg)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Enzyl 80 Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, fractures, falls, dry skin, pruritus,decreased appetite, and constipation might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.

Uses of Enzyl Capsule

Treatment of Prostate cancer

Benefits of Enzyl Capsule

Treatment of Prostate cancer
Prostate cancer is a condition where abnormal cells grow in the prostate gland, which can spread to other parts of the body if untreated. Enzyl 80 Capsule helps block the action of male hormones that promote cancer growth, slowing disease progression and improving survival outcomes.

Side effects of Enzyl Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Enzyl

Headache
Hot flashes
Weakness
High blood pressure
Fatigue
Decreased appetite
Constipation
Dry skin
Itching
Fall
Fracture

How to use Enzyl Capsule

Take this medicine in the dose and duration as advised by your doctor. Enzyl 80 Capsule may be taken with or without food.

How Enzyl Capsule works

Enzyl 80 Capsule is an antiandrogen. It works by blocking the effect of the natural male hormones on the growth of prostate cells.

All substitutes for Enzyl 80 Capsule

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You have been prescribed Enzyl 80 Capsule for the treatment of prostate cancer.
Take it with or without food, preferably at the same time every day.
Do not drive or do anything requiring concentration unless you know how Enzyl 80 Capsule affects you.
It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
If you are diabetic, monitor your blood glucose regularly while taking Enzyl 80 Capsule.
Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not stop taking the medication without talking to your doctor first.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Enzyl 80 Capsule.

Pregnancy

UNSAFE

Enzyl 80 Capsule is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Enzyl 80 Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Enzyl 80 Capsule may cause side effects that could affect your ability to drive.

Kidney

CAUTION

Enzyl 80 Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Enzyl 80 Capsule is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Enzyl with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Nevirapine (Oral Route)

Do not consume Nevirapine with Enzalutamide. Enzalutamide may reduce blood levels of Nevirapine.

Severe

Bortezomib (Injection Route)

Avoid concurrent use. Please consult with your doctor. Enzalutamide may reduce efficacy of Bortezomib.

Severe

Irinotecan (Injection Route)

Do not consume Irinotecan with Enzalutamide. Enzalutamide may fasten the elimination of Irinotecan and its active form.

Severe

Sirolimus (Injection Route)

Do not consume Sirolimus with Enzalutamide. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Enzalutamide may reduce blood levels of Sirolimus.

Severe

Aprepitant (Oral Route)

Do not consume Aprepitant with Enzalutamide. Enzalutamide may reduce blood levels of Aprepitant.

Frequently asked questions

What is Enzyl 80 Capsule used for?

Enzyl 80 Capsule is used to treat prostate cancer that has spread, or is resistant to hormone therapy. It works by blocking the effect of male hormones (androgens) that help cancer cells grow.

Who should not take Enzyl 80 Capsule?

People should not take Enzyl 80 Capsule if they are allergic to it or any of its ingredients. It is also not recommended for women, especially during pregnancy, due to the risk of harm to an unborn baby.

Can Enzyl 80 Capsule cause seizures?

Yes, Enzyl 80 Capsule can increase the risk of seizures. Patients with a history of seizures, brain injury, stroke, or those taking medicines that lower the seizure threshold need extra caution.

What are the serious side effects of Enzyl 80 Capsule?

Serious side effects of Enzyl 80 Capsule may include seizures, severe allergic reactions, sudden chest pain, shortness of breath, swelling in legs, falls, memory problems, or unusual bleeding. Seek medical attention right away if these occur.

Can Enzyl 80 Capsule affect memory or thinking?

Yes, Enzyl 80 Capsule may cause problems such as memory loss, confusion, trouble concentrating, or a higher risk of falls. These side effects may impact daily activities.

Does Enzyl 80 Capsule affect blood pressure or heart health?

Yes, Enzyl 80 Capsule can cause high blood pressure, and may increase the risk of heart problems such as heart attack, or heart failure. Regular monitoring is important, especially if you already have heart disease.

Does Enzyl 80 Capsule affect fertility in men?

Yes, Enzyl 80 Capsule may reduce fertility in men, and can harm an unborn child if the father is taking it during conception. Effective contraception is recommended during treatment, and for at least 3 months after stopping.

Fact Box

Chemical Class

Phenylimidazolidines

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Androgen Receptor Antagonists

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 474-75.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Enzalutamide [Product Information]. Netherlands: Astellas Pharma Europe B.V.; [Accessed on 27 Mar. 2019] (online) Available from:
CiplaMed: Enzalutamide [Prescribing Information]. 2022. [Accessed 20 Feb. 2024] (online) Available from:
Enzalutamide [Product Monograph]. Markham, ON: Astellas Pharma Canada, Inc.; 2020. [Accessed 14 Mar. 2026] (online) Available from:
Enzalutamide [Prescribing Information]. Northbrook, IL: Astellas Pharma US, Inc.; 2018. [Accessed 14 Mar. 2026] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Acme Plaza, Andheri-Kurla Road, Andheri (East), Mumbai, Maharashtra -400059

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Enzyl 80 Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Enzyl 80 Capsule

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Enzyl Capsule

Benefits of Enzyl Capsule

Side effects of Enzyl Capsule

How to use Enzyl Capsule

How Enzyl Capsule works

All substitutes for Enzyl 80 Capsule

Enzamide 80 Capsule

Azel 80 Capsule

Obnyx 80 Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Nevirapine (Oral Route)

Bortezomib (Injection Route)

Irinotecan (Injection Route)

Sirolimus (Injection Route)

Aprepitant (Oral Route)

Frequently asked questions

What is Enzyl 80 Capsule used for?

Who should not take Enzyl 80 Capsule?

Can Enzyl 80 Capsule cause seizures?

What are the serious side effects of Enzyl 80 Capsule?

Can Enzyl 80 Capsule affect memory or thinking?

Does Enzyl 80 Capsule affect blood pressure or heart health?

Does Enzyl 80 Capsule affect fertility in men?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests